Analysis in clinical features of acute pontine infarction patients with imaging manifestation as "pontine hemisection sign"

HUAN Zhifei; ZHU Youling; XU Qiaoqiao

doi:10.7619/jcmp.20211976

Journal of Clinical Medicine in Practice > 2021 > 25(17): 22-26. > DOI: 10.7619/jcmp.20211976

HUAN Zhifei, ZHU Youling, XU Qiaoqiao. Analysis in clinical features of acute pontine infarction patients with imaging manifestation as "pontine hemisection sign"[J]. Journal of Clinical Medicine in Practice, 2021, 25(17): 22-26. DOI: 10.7619/jcmp.20211976

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Analysis in clinical features of acute pontine infarction patients with imaging manifestation as "pontine hemisection sign"

Department of Neurology, the Third Affiliated Hospital of Anhui Medical University, Hefei City First People′s Hospital of Anhui Province, Hefei, Anhui, 230061

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Received Date: May 11, 2021
Available Online: September 03, 2021
Published Date: September 14, 2021

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Abstract

Abstract

Objective To investigate the clinical features, etiology and outcomes of acute pontine infarction patients with imaging manifestation as "pontine hemisection sign".
Methods Clinical materials of 11 acute pontine infarction patients with imaging manifestation as "pontine hemisection sign" were collected, and their clinical manifestations, imaging features, etiology and outcomes were retrospectively analyzed based on literature review.
Results The morphology of magnetic resonance imaging (MRI) in 11 patients with acute pontine infarction showed "pontine hemisection sign". All the patients were acute onset, with an average age of (72.64±8.26) years old, and the main risk factors were hypertension, diabetes and hyperlipidemia. The clinical symptoms of 11 patients were contralateral limb paralysis and dysarthria, accompanied by contralateral hemiparesis in 5 cases, central facial paralysis in 8 cases, central lingual paralysis in 7 cases, vertigo or dizziness in 5 cases, nystagmus in 4 cases and ataxia in 3 cases. The mean National Institutes of Health Stroke Scale (NIHSS) score of 11 patients at discharge was (4.91±2.54) points. MRI examination of all patients showed that the lesions involved the ventral, medial and medial areas of pons, of which 3 cases involved the anterolateral area. Severe stenosis or occlusion of vertebrobasilar artery was found in 3 patients by magnetic resonance angiography (MRA).
Conclusion "Pontine hemisection sign" is a special imaging sign of acute pontine infarction, the typical clinical manifestations are sudden onset contralateral limb paralysis, dysarthria and central facial paralysis, which can be accompanied by symptoms such as vertigo and nystagmus. Its main etiological mechanism is basilar artery branch degeneration and large artery occlusive disease, and most patients have a good clinical prognosis.

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Analysis in clinical features of acute pontine infarction patients with imaging manifestation as "pontine hemisection sign"

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