Value of serum uric acid combined with Gensini score in predicting prognosis of patients with acute ST segment elevation myocardial infarction

ZHONG Yanhua; SANG Shengmin; DING Hongsheng

doi:10.7619/jcmp.20212716

Journal of Clinical Medicine in Practice > 2021 > 25(23): 82-85. > DOI: 10.7619/jcmp.20212716

ZHONG Yanhua, SANG Shengmin, DING Hongsheng. Value of serum uric acid combined with Gensini score in predicting prognosis of patients with acute ST segment elevation myocardial infarction[J]. Journal of Clinical Medicine in Practice, 2021, 25(23): 82-85. DOI: 10.7619/jcmp.20212716

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Value of serum uric acid combined with Gensini score in predicting prognosis of patients with acute ST segment elevation myocardial infarction

Department of Cardiology, Haian People's Hospital in Jiangsu Province, Nantong, Jiangsu, 226600

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Received Date: July 04, 2021
Available Online: November 14, 2021
Published Date: December 14, 2021

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Abstract

Abstract

Objective To investigate the value of serum uric acid combined with Gensini score in predicting prognosis of patients with acute ST segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI).
Methods A total of 408 STEMI patients treated with PCI were selected as study objects, among whom 64 cases with Major Adverse Cardiovascular Events (MACE) were included in observation group, and 344 cases without MACE were included in the control group. Coronary artery lesions, serum uric acid, Gensini score and other biochemical indexes were compared between the two groups.
Results The average age, the proportion of patients with history of diabetes, fasting blood glucose, serum uric acid and Gensini scores in the observation group were significantly higher than those in the control group (P < 0.05). Age, history of diabetes, serum uric acid and Gensini score were independent influencing factors of MACE after PCI (P < 0.05). The sensitivity and specificity of serum uric acid and Gensini score in combination in predicting MACE were significantly higher than those of serum uric acid and Gensini score(P < 0.05).
Conclusion Serum uric acid and Gensini score are closely related to the prognosis of STEMI patients after PCI. The combination of the two indexes can effectively predict the risk of MACE.
- serum uric acid,
- Gensini score,
- myocardial infarction,
- percutaneous coronary intervention,
- prognosis

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[1]	张云雁. 女性急性心肌梗死的特点研究进展[J]. 东南国防医药, 2018, 20(3): 276-280. doi: 10.3969/j.issn.1672-271X.2018.03.013
[2]	李龙, 谢翔. ST段抬高型急性心肌梗死合并多支血管病变经皮冠状动脉介入治疗方案选择研究进展[J]. 中华实用诊断与治疗杂志, 2018, 32(4): 395-398.
[3]	梁云亮, 盖婉丽, 李森杰, 等. Ang1、Ang2与急性心肌梗死病人预后的关系探讨[J]. 中西医结合心脑血管病杂志, 2019, 17(9): 1343-1346.
[4]	赖敏华, 李静芝, 陈凌, 等. 冠心病患者PCI术后全因死亡率、再入院率及其影响因素分析[J]. 实用医学杂志, 2020, 36(6): 801-807. doi: 10.3969/j.issn.1006-5725.2020.06.019
[5]	中华医学会心血管病学分会, 中华心血管病杂志编辑委员会. 急性ST段抬高型心肌梗死诊断和治疗指南[J]. 中华心血管病杂志, 2015, 43(5): 380-393. doi: 10.3760/cma.j.issn.0253-3758.2015.05.003
[6]	GENSINI G G. A more meaningful scoring system for determining the severity of coronary heart disease[J]. Am J Cardiol, 1983, 51(3): 606. doi: 10.1016/S0002-9149(83)80105-2
[7]	闫洁, 袁森. 急性心肌梗死PCI术后近期MACE的危险因素及血小板功能参数的预测作用[J]. 中国动脉硬化杂志, 2020, 28(12): 58-65.
[8]	吕赛, 周玉杰, 刘巍. 高尿酸血症、代谢综合征与冠心病的研究进展[J]. 心肺血管病杂志, 2018, 37(1): 76-78. doi: 10.3969/j.issn.1007-5062.2018.01.019
[9]	王小华, 王伟, 张妮. 血清脂蛋白(a)、尿酸及血浆同型半胱氨酸水平与冠心病、脑梗死的相关性分析[J]. 中西医结合心脑血管病杂志, 2019, 17(16): 2408-2411. doi: 10.12102/j.issn.1672-1349.2019.16.003
[10]	刘新民, 董建增, 刘小慧, 等. 无症状高尿酸血症对择期经皮冠状动脉介入治疗术后病死率的影响[J]. 中华医学杂志, 2017, 97(7): 508-511. doi: 10.3760/cma.j.issn.0376-2491.2017.07.007
[11]	贾金瑞, 于健. 急性心肌梗死患者血尿酸浓度、killip分级对死亡的预测价值[J]. 岭南心血管病杂志, 2018, 24(2): 146-149. doi: 10.3969/j.issn.1007-9688.2018.02.06
[12]	刘冰, 洪权, 冯哲. 高糖与高尿酸通过醛糖还原酶通路协同作用加重内皮细胞损伤[J]. 中华肾病研究电子杂志, 2018, 7(1): 34-38. doi: 10.3877/cma.j.issn.2095-3216.2018.01.008
[13]	MAZIDI M, KATSIKI N, BANACH M. Α higher ratio of serum uric acid to serum creatinine could predict the risk of total and cause specific mortality- insight from a US national survey[J]. Int J Cardiol, 2021, 326: 189-193. doi: 10.1016/j.ijcard.2020.05.098
[14]	陈继舜, 刘晓唤, 钱航, 等. Gensini评分和HsCRP在预测PCI术后支架内再狭窄的价值[J]. 西安交通大学学报: 医学版, 2018, 39(3): 336-340.
[15]	石鑫岳, 王静, 刘暘. 冠心病患者血尿酸与血脂和冠脉病变数量相关[J]. 基础医学与临床, 2019, 39(2): 245-246. doi: 10.3969/j.issn.1001-6325.2019.02.020

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Value of serum uric acid combined with Gensini score in predicting prognosis of patients with acute ST segment elevation myocardial infarction

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