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GONG Zan, CHEN Weidong, PAN Fan, GAO Xinyue, QIAN Zhongxin, WANG Yisheng. Correlation between cerebral state index and end-tidal concentration of sevoflurane in children with cerebral palsy undergoing adjustment surgery[J]. Journal of Clinical Medicine in Practice, 2021, 25(19): 20-23, 29. DOI: 10.7619/jcmp.20213060
Citation: GONG Zan, CHEN Weidong, PAN Fan, GAO Xinyue, QIAN Zhongxin, WANG Yisheng. Correlation between cerebral state index and end-tidal concentration of sevoflurane in children with cerebral palsy undergoing adjustment surgery[J]. Journal of Clinical Medicine in Practice, 2021, 25(19): 20-23, 29. DOI: 10.7619/jcmp.20213060
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Correlation between cerebral state index and end-tidal concentration of sevoflurane in children with cerebral palsy undergoing adjustment surgery

  • 1.

    Department of Anesthesiology, Punan Hospital of Pudong New Area in Shanghai, Shanghai, 200125

  • 2.

    Department of Anesthesiology, the Sixth People's Hospital in Shanghai, Shanghai, 200233

  • 3.

    Department of Neurosurgery, Punan Hospital of Pudong New Area in Shanghai, Shanghai, 200125

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  • Received Date: July 28, 2021
  • Available Online: October 10, 2021
  • Published Date: October 14, 2021
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    • Abstract
  •   Objective  To investigate the correlation between cerebral state index (CSI) and end-tidal concentration of sevoflurane (CETSev) in children with cerebral palsy during sevoflurane general anesthesia.
      Methods  Eighty children with cerebral palsy for selective lower limb adjustment surgery were selected. Sevoflurane general anesthesia and routine monitoring were performed, and CETSev as well as CSI were continuously monitored. Before induction (T0), after laryngeal mask implantation (T1), CETSev 0.8% (T2), CETSev 1.2% (T3), CETSev 1.6% (T4), CETSev 2.0%(T5), CETSev 2.4% (T6), CETSev 2.8% (T7), stop taking sevoflurane (T8) and declining stages including CETSev 1.4% (T9), CETSev 1.2%(T10), CETSev 1.0% (T11), CETSev 0.8% (T12), CETSev 0.6% (T13), CETSev 0.4% (T14), before (T15) and after (T16) laryngeal mask removal, the values of CETSev and CSI were recorded. The correlation between CETSev and CSI introduction was analyzed.
      Results  During the rising period of CETSev (T0 to T7), the CSI of T2 to T7 was significantly lower than that of T0 (P < 0.05); CSI was negatively correlated with CETSev (r=-0.890, P < 0.001). During the decreasing period of CETSev (T8 to T16), CSI values of T9 to T16 were significantly higher than that of T8 (P < 0.05); CSI was negatively correlated with CETSev (r=-0.889, P < 0.001).
      Conclusion  There is a significant negative correlation between CSI and CETSev in the rising and descending period of CETSev in children with cerebral palsy undergoing palsy adjustment surgery. Therefore, CSI can be used to guide the accurate use of sevoflurane during general anesthesia.
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    • References (14)
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