Objective To retrospectively analyze the characteristics of missed diagnosed and misdiagnosed cases by breast ultrasound examination in early diagnosis of breast cancer and their influencing factors.
Methods A total of 128 false negative (missed diagnosis) and false positive (misdiagnosed) patients for breast cancer diagnosed by breast ultrasound examination were included in this study. Their characteristics of missed and misdiagnosed cases were analyzed, and multivariate unconditional Logistic regression analysis was used to explore the independent influencing factors of missed and misdiagnosis in the early diagnosis of breast cancer.
Results Among the 128 patients, there were 89 false negative (missed diagnosis) cases and 39 false positive (misdiagnosed) cases. There was a statistically significant difference in blood flow distribution between missed and misdiagnosed patients (P < 0.05). Logistic regression analysis showed that peripheral blood supply or no blood flow in the lesions, microcalcification, and positive axillary lymph nodes of the lesion were independent influencing factors of missed diagnosis by breast ultrasound examination in the early diagnosis of breast cancer (P < 0.05). Blood flow signals, axillary lymph node enlargement, single mass and nodule, and inflammatory lesions were all independent factors influencing the misdiagnosis by breast ultrasound in the early diagnosis of breast cancer (P < 0.05).
Conclusion Peripheral blood supply or no blood flow, microcalcification, and positive axillary lymph nodes are independent influencing factors of missed diagnosis by breast ultrasound examination. Blood flow signals, axillary lymph nodes enlargement, single mass nodules, and inflammatory lesions are independent influencing factors for misdiagnosis by breast ultrasound examination.
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