Analysis in influencing factors of complications in early esophageal cancer and precancerous lesions after endoscopic treatment

HAN Yonghuan

doi:10.7619/jcmp.20213719

Journal of Clinical Medicine in Practice > 2022 > 26(2): 123-127. > DOI: 10.7619/jcmp.20213719

HAN Yonghuan. Analysis in influencing factors of complications in early esophageal cancer and precancerous lesions after endoscopic treatment[J]. Journal of Clinical Medicine in Practice, 2022, 26(2): 123-127. DOI: 10.7619/jcmp.20213719

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Analysis in influencing factors of complications in early esophageal cancer and precancerous lesions after endoscopic treatment

HAN Yonghuan

Department of Gastroenterology, Affiliated Hospital of Chifeng University, Chifeng, Inner Mongolia, 024000

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Received Date: September 14, 2021
Available Online: April 13, 2021
Published Date: January 27, 2022

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Abstract

Abstract

Objective To explore the influencing factors of complications in early esophageal cancer and precancerous lesions after endoscopic treatment.
Methods A total of 268 patients with early esophageal cancer or precancerous lesions who underwent endoscopic treatment were selected as research objects, their clinical data were retrospectively analyzed, and the influencing factors of related complications were analyzed by univariate and multivariate Logistic regression analysis.
Results A total of 69 cases (with the overall complication rate of 25.75%) of 268 patients had complications, including delayed bleeding in 11 cases (4.10%), esophageal perforation in 12 cases (4.48%), and esophageal stenosis in 46 cases (17.16%). Univariate and multivariate Logistic regression analysis showed that lesion diameter and lesion circumference were independent influential factors of delayed postoperative bleeding (P < 0.05), surgical method was independent influential factors of esophageal perforation (P < 0.05), lesion circumference and operative time were independent influential factors of esophageal stenosis (P < 0.05).
Conclusion Patients with early esophageal cancer and precancerous lesions are prone to occur delayed bleeding, esophageal perforation and esophageal stenosis after endoscopic treatment, among which the independent influencing factors of delayed bleeding are lesion diameter and lesion circumference, the independent influencing factors of esophageal perforation are lesion circumference and operative time. In order to improve the prognosis and quality of life of patients, surgeons should take corresponding preventive measures according to the influencing factors of complications.
- endoscopic treatment,
- early esophageal cancer,
- precancerous lesions,
- complications,
- perforation,
- delayed bleeding

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[1]	TATE D J, KLEIN A, SIDHU M, et al. Endoscopic submucosal dissection for suspected early gastric cancer: absolute versus expanded criteria in a large Western cohort (with video)[J]. Gastrointest Endosc, 2019, 90(3): 467-479. doi: 10.1016/j.gie.2019.04.242
[2]	徐美东, 初元. 内镜治疗早期食管癌和癌前病变的现状与展望[J]. 同济大学学报: 医学版, 2019, 40(5): 535-541. https://www.cnki.com.cn/Article/CJFDTOTAL-TJIY201905003.htm
[3]	LIBÃNIO D, PIMENTEL-NUNES P, DINIS-RIBEIRO M. Complications of endoscopic resection techniques for upper GI tract lesions[J]. Best Pract Res Clin Gastroenterol, 2016, 30(5): 735-748. doi: 10.1016/j.bpg.2016.09.010
[4]	SONG S, WANG X, ZHANG S, et al. Efficacy and complications of submucosal tunneling endoscopic resection for upper gastrointestinal submucosal tumors and exploration for influencing factors[J]. Z Gastroenterol, 2018, 56(4): 365-373. doi: 10.1055/s-0043-123765
[5]	徐法贞, 黄曙, 李桂芹, 等. 内镜下联合治疗肝硬化并发食管胃底静脉曲张破裂出血的效果观察[J]. 中国临床保健杂志, 2019, 22(4): 542-545. doi: 10.3969/J.issn.1672-6790.2019.04.029
[6]	AHMED Y, OTHMAN M. EMR/ESD: techniques, complications, and evidence[J]. Curr Gastroenterol Rep, 2020, 22(8): 39. doi: 10.1007/s11894-020-00777-z
[7]	UEKI N, FUTAGAMI S, AKIMOTO T, et al. Effect of antithrombotic therapy and long endoscopic submucosal dissection procedure time on early and delayed postoperative bleeding[J]. Digestion, 2017, 96(1): 21-28. doi: 10.1159/000475924
[8]	HARADA H, NAKAHARA R, MURAKAMI D, et al. The effect of anticoagulants on delayed bleeding after colorectal endoscopic submucosal dissection[J]. Surg Endosc, 2020, 34(8): 3330-3337. doi: 10.1007/s00464-019-07101-5
[9]	ONO H, YAO K, FUJISHIRO M, et al. Guidelines for endoscopic submucosal dissection and endoscopic mucosal resection for early gastric cancer (second edition)[J]. Dig Endosc, 2021, 33(1): 4-20. doi: 10.1111/den.13883
[10]	MANES G, PASPATIS G, AABAKKEN L, et al. Endoscopic management of common bile duct stones: European Society of Gastrointestinal Endoscopy (ESGE) guideline[J]. Endoscopy, 2019, 51(5): 472-491. doi: 10.1055/a-0862-0346
[11]	GONG J, ZHOU B Y, LIANG C B, et al. Comparison between tunneling and standard endoscopic submucosal dissection for treatment of large esophageal superficial neoplasm[J]. Acta Gastroenterol Belg, 2019, 82(4): 469-474.
[12]	DAN X, LV X H, SAN Z J, et al. Efficacy and safety of multiband mucosectomy versus cap-assisted endoscopic resection for early esophageal cancer and precancerous lesions: a systematic review and meta-analysis[J]. Surg Laparosc Endosc Percutan Tech, 2019, 29(5): 313-320. doi: 10.1097/SLE.0000000000000711
[13]	SPADACCINI M, MASELLI R, GALTIERI P A, et al. t01.02.1 efficacy and safety of multi-band mucosectomy for barrett's esophagus: a single center Italian experience[J]. Dig Liver Dis, 2020, 52: S62.
[14]	YU X Y, CHEN J, YUAN Z Q, et al. Endoscopic resection techniques for squamous premalignant lesions and early carcinoma of the esophagus: ER-Cap, MBM, and ESD, how do we choose A multicenter experience[J]. Therap Adv Gastroenterol, 2020, 13: 1756284820909172.
[15]	BELGHAZI K, MARCON N, TESHIMA C, et al. Risk factors for serious adverse events associated with multiband mucosectomy in Barrett's esophagus: an international multicenter analysis of 3827 endoscopic resection procedures[J]. Gastrointest Endosc, 2020, 92(2): 259-268. e2. doi: 10.1016/j.gie.2020.03.3842
[16]	QIU Y, SHI R. Roles of steroids in preventing esophageal stricture after endoscopic resection[J]. Can J Gastroenterol Hepatol, 2019, 2019: 5380815.
[17]	ISHIHARA R. Prevention of esophageal stricture after endoscopic resection[J]. Dig Endosc, 2019, 31(2): 134-145. doi: 10.1111/den.13296
[18]	ABE S, IYER P G, ODA I, et al. Approaches for stricture prevention after esophageal endoscopic resection[J]. Gastrointest Endosc, 2017, 86(5): 779-791. doi: 10.1016/j.gie.2017.06.025

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Analysis in influencing factors of complications in early esophageal cancer and precancerous lesions after endoscopic treatment

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