Study on inactivation effect of quaternary ammonium salts disinfectant concentrate and quaternary ammonium salts disinfectant wipes on severe acute respiratory syndrome coronavirus-2

  Objective  To study the inactivation effect of QUAT disinfectant concentrate and QUAT disinfectant wipes on severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

  Methods  The suspension quantitative killing test method was used to analyze the effect of the QUAT disinfectant concentrate and QUAT disinfectant wipes in inactivating the SARS-CoV-2.

  Results  The main ingredients of the QUAT disinfectant concentrate and QUAT disinfectant wipes were four single and double-chain quaternary ammonium salts mixtures, and the inactivation log value of novel coronavirus SARS-CoV-2 in suspension was greater than 4.0 when the concentration was 432 mg/L and the action time was 1 min. The squeezed solution of the QUAT disinfectant wipes prepared with the QUAT disinfectant concentrate had a concentration of 820 mg/L, the logarithmic value of inactivation of the SARS-CoV-2 in the suspension was greater than 4.0 when the action time was 1 min.

  Conclusion  The QUAT disinfectant concentrate and QUAT disinfectant wipes can quickly and effectively inactivate the SARS-CoV-2 at low concentrations.