Effect of dexmedetomidine combined with different doses of sufentanil on airway response of patients with adenoidectomy

Objective To investigate the effect of dexmedetomidine combined with different doses of sufentanil on airway response of child patients with adenoidectomy.

Methods A total of 113 child patients with selective adenotonsillectomy under general intravenous anesthesia were selected and divided into different groups according to the dose of sufentanil. The change of vital signs, differences of airway response and choking after awakening of child patients were analyzed.

Results In the combination of dexmedetomidine and low-dose sufentanil, the heart rate and mean arterial pressure of child patients were significantly higher than those with dexmedetomidine and other doses of sufentanil, and excessive high-dose sufentanil led to the significant reduction of heart rate and mean arterial pressure of child patients than those of the other groups (P < 0.05); with the increase of dose of sufentanil, the peak airway pressure decreased, and the incidence rates of choking and agitation after awakening decreased as well.

Conclusion Dexmedetomidine combined with different doses of sufentanil can inhibit airway response during adenoidectomy, and the inhibitory effect is better with the increase of dose of sufentanil.