Effects of three therapeutic schedules on cardiac functionand prognosis in patients undergoing percutaneous coronary intervention

Objective To observe the efficacy of three different therapeutic schedules in patients undergoing percutaneous coronary intervention (PCI), and to explore the value of enhanced external counterpulsation (EECP) and cardiac rehabilitation in evaluating cardiac function and prognosis of patients after PCI.

Methods A total of 150 patients after PCI were selected as research objects, and randomly divided into group A, group B and group C, with 50 cases in each group. The group A received conventional drug therapy, the group B received conventional drug combined with cardiac rehabilitation therapy, and the group C received conventional drug therapy, cardiac rehabilitation and EECP. The bilirubin lipid composite index low-density lipoprotein cholesterol (LDL-C)/high-density lipoprotein cholesterol (HDL-C) and total bilirubin (TBIL), homocysteine (Hcy), left ventricular ejection fraction (LVEF), 6-minute walk test6-minute walk distance (6MWD) and SF-36 Scale score were observed before and after treatment in the three groups; the incidence of adverse cardiovascular events was recorded and compared among the three groups.

Results After treatment, the levels of LDL-C/(HDL-C and TBIL) and Hcy were significantly lower than those before treatment, and the levels of LDL-C/(HDL-C and TBIL) and Hcy in the groups A, B and C were significantly decreased (P < 0.05); the 6MWD, LVEF and item score of SF-36 Scale were significantly higher than those before treatment, and LVEF and 6MWD in the groups A, B and C were significantly increased (P < 0.05); in the SF-36 Scale scores, there was no significant difference in the social function score between group C and group B (P>0.05), and the social function score of the group C was significantly higher than that of the group A (P < 0.05); the other scores in the groups A, B and C showed significant increase trend (P < 0.05). The incidence of adverse cardiovascular events in the three groups was significantly decreased (group C < group B < group A, P < 0.05).

Conclusion On the basis of drug therapy, cardiac rehabilitation combined with EECP can significantly improve cardiac function, quality of life and prognosis of patients after PCI, and the therapeutic effect is significantly better than cardiac rehabilitation training and drug therapy alone.