WANG Hui, WEI Jinrong, HE Zhengfei. Efficacy of external application therapy of traditional Chinese medicine in treatment of cancer pain[J]. Journal of Clinical Medicine in Practice, 2022, 26(13): 110-112,118. DOI: 10.7619/jcmp.20220950
Citation: WANG Hui, WEI Jinrong, HE Zhengfei. Efficacy of external application therapy of traditional Chinese medicine in treatment of cancer pain[J]. Journal of Clinical Medicine in Practice, 2022, 26(13): 110-112,118. DOI: 10.7619/jcmp.20220950

Efficacy of external application therapy of traditional Chinese medicine in treatment of cancer pain

More Information
  • Received Date: March 20, 2020
  • Available Online: July 01, 2022
  • Objective 

    To observe the efficacy of external application therapy of traditional Chinese medicine on cancer pain.

    Methods 

    Data of 274 patients treated with traditional Chinese medicine application therapy of Kangai Zhitong Formula in oncology department of Yangzhou Hospital of Traditional Chinese Medicine in Jiangsu Province were retrospectively analyzed. According to Numerical Rating Scale (NRS) score before treatment, 274 patients were divided into mild pain group (n=175, NRS score of 1 to 3) and moderate pain group (n=99, NRS score of 4 to 6). The overall curative effect of traditional Chinese medicine application therapy and curative effects of patients with mild and moderate cancer pain were observed.

    Results 

    Among 274 patients, 41 patients were treated with morphine for breakthrough pain due to increased NRS score. The response rate and control rates of pain were 78.9% and 97.1% in the mild pain group, 48.5% and 58.6% in moderate pain group. The response rates and control rates of patients in the mild pain group were higher than those in the moderate pain group (P<0.05). The response rates of patients with NRS score of 1, 2 and 3 were 82.2%, 79.7% and 76.1%, and pain control rates of patients with NRS score of 1, 2 and 3 were 97.8%, 96.6%and 97.2%, there were no significant differences in pain control rate and response rates among patients with scores of 1, 2 and 3 after application therapy(P=0.939). The response rates were 75.8%, 48.0%and 26.8% for patients with NRS score of 4, 5 and 6. Response rates of patients with NRS score of 4 were higher than those with NRS score of 5 and 6 (P<0.05), while there was no statistically significant difference in response rates after application therapy between patients with NRS score of 5 and 6 (P=0.08).

    Conclusion 

    For patients with NRS score≤3, traditional Chinese medicine application therapy is an effective treatment. For patients with NRS score of 4, the application of traditional Chinese medicine application therapy can still achieve good therapeutic effect, but the efficacy and pain control rate of traditional Chinese medicine application therapy are low for patients with NRS score of 5 and 6, therefore, auxiliary analgesia is needed for them.

  • [1]
    World Health Organization. WHO Guidelines for the Pharmacological and radiotherapeutic management of cancer pain in adults and adolescents[R]. Geneva: World Health Organization, 2018.
    [2]
    荣震, 闭雪瑶, 甘芷川, 等. 中药外敷联合西药治疗癌痛的研究进展[J]. 湖南中医杂志, 2017, 33(7): 204-206. https://www.cnki.com.cn/Article/CJFDTOTAL-HNZO201707082.htm
    [3]
    袁珺, 郁文恺, 毛懿雯. 中药贴敷法治疗肝肺癌晚期疼痛的临床观察[J]. 中国中医药科技, 2020, 27(6): 932-933. https://www.cnki.com.cn/Article/CJFDTOTAL-TJYY202006039.htm
    [4]
    吴晋芳, 陈高峰. 中药穴位贴敷辅助治疗癌痛的临床疗效[J]. 长春中医药大学学报, 2020, 36(2): 332-335. https://www.cnki.com.cn/Article/CJFDTOTAL-CZXX202002037.htm
    [5]
    颜芳, 黄成成, 路富民, 等. 癌痛的分子机理研究进展[J]. 生物技术通讯, 2016, 27(5): 711-715. doi: 10.3969/j.issn.1009-0002.2016.05.024
    [6]
    刘延庆. 癌性疼痛的中医药治疗[J]. 江苏中医药, 2008, 40(9): 8-9. doi: 10.3969/j.issn.1672-397X.2008.09.006
    [7]
    赵志正, 刘杰, 林洪生. 中医药治疗癌性疼痛研究进展[J]. 世界中医药, 2014, 9(7): 851-856. doi: 10.3969/j.issn.1673-7202.2014.07.006
    [8]
    刘保松, 白明, 彭孟凡, 等. 癌痛中医药的外治疗法及特点分析[J]. 中南药学, 2018, 16(3): 362-365. https://www.cnki.com.cn/Article/CJFDTOTAL-ZNYX201803017.htm
    [9]
    孙帅, 俞超芹, 张丹英, 等. 大黄、皮硝外敷改善转移性癌性骨痛临床研究[J]. 辽宁中医药大学学报, 2019, 21(2): 82-85. https://www.cnki.com.cn/Article/CJFDTOTAL-LZXB201902023.htm
    [10]
    唐翠娟, 莫春梅, 荣震, 等. 中医外治癌痛的组方规律分析[J]. 中医药导报, 2019, 25(17): 18-22. https://www.cnki.com.cn/Article/CJFDTOTAL-HNZB201917006.htm
    [11]
    毛毛, 孙永浩, 张金兰. "癌痛消"外敷联合三阶梯止痛法治疗中重度癌痛68例临床研究[J]. 江苏中医药, 2016, 48(5): 49-51. https://www.cnki.com.cn/Article/CJFDTOTAL-JSZY201605022.htm
    [12]
    朱玲琦, 杨铭, 杜文民, 等. 5277例中药不良反应分析[J]. 中国临床药学杂志, 2010, 19(5): 313-316. https://www.cnki.com.cn/Article/CJFDTOTAL-LCZZ201005018.htm
    [13]
    刘志宏, 刘香弟. 中医护理技术临床应用现状与展望[J]. 中国护理管理, 2013, 13(10): 14-16 https://www.cnki.com.cn/Article/CJFDTOTAL-GLHL201310007.htm
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