Research progress in non-coding RNA in radon-induced lung cancer
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Abstract
The incidence and mortality of lung cancer are in the forefront of all cancers in the world. Radon and its daughters are the second biggest risk factors after smoking. Non-coding RNA is an essential regulator of biological processes and affects tumor development through epigenetic, transcriptional, and post-transcriptional regulation of cell development, proliferation differentiation, and apoptosis. However, the mechanism of the role of non-coding RNA in radon-induced lung cancer is unclear. This paper mainly reviewed the non-coding RNAs aberrantly expressed in tissues of radon-induced lung cancer and elaborated on its mechanism in radon-induced lung cancer so as to provide new ideas for prevention and clinical treatment of radon-induced lung cancer.
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