Risk factors of delirium in patients with severe multiple trauma in trauma center

Objective  To investigate the occurrence and risk factors of delirium in patients with severe multiple injuries in trauma center.

Methods  A total of 168 patients with severe multiple injuries admitted from June 2021 to January 2022 were selected. The occurrence of delirium was assessed by the Confusion Assessment Method (CAM), and the patients were divided into delirium group (n=65) and non-delirium group (n=103) according to whether delirium occurred. The data of patients were collected and the risk factors of delirium were analyzed.

Results  Clinical data of 168 patients with severe multiple injuries in trauma center were collected, including 65 patients with delirium, with an incidence of 38.69%. There were significant differences in age, mechanical ventilation, hypoxemia (arterial partial pressure of oxygen < 60 mmHg), transferring from ICU to trauma center, coma during trauma, complicating with history of hypertension, brain trauma, invasive operation, and more serious disease between the two groups (P < 0.05). Multivariate Logistic regression analysis showed that age >60 years, mechanical ventilation, hypoxemia (arterial partial pressure of oxygen < 60 mmHg), transferring from ICU to trauma center, coma at the time of trauma, history of hypertension, traumatic brain injury, invasive procedures and severity of illnessAcute Physiology and Chronic Health Evaluation Ⅱ (APACHE Ⅱ) score>21 scoreswere independent risk factors for delirium in patients with severe multiple trauma in trauma center.

Conclusion  Patients with severe multiple injuries in trauma center have higher incidence of delirium that involves many independent risk factorsand exerts influences in a wide range, so the measures should be taken in time when the problems are detected.