Analysis of adverse events and psychological statusin 71 patients with acute organophosphorus pesticide poisoning

Objective To investigate the adverse events and psychological status of patients with acute organophosphorus pesticide poisoning (AOPP).

Methods A convenient sampling method was used to select 71 hospitalized patients with AOPP from January 2020 to September 2021 as research objects, and the general information questionnaire, adverse event questionnaire and mental Status Scale in Non-psychiatric Settings (MSSNS) were used to conduct surveys.

Results Among 71 patients, 14 patients had adverse events, and the incidence rate was 19.72% (14/71). The score of each dimension and total score of MSSNS in 71 patients with AOPP were significantly higher than those of normal controls (P < 0.05). In this study, there were 23 cases (32.39%) with mild abnormality and 9 cases (12.68%) with moderate to severe abnormality, and the total abnormality rate was 45.07% (32/71). The univariate analysis showed that the anxiety of people under 30 years old was significantly more serious, and the scores of depression, loneliness and anger and total score in people over 45 years old were significantly higher than those in other age groups (P < 0.05); the anxiety score and total score of people with education level of primary school and below were significantly higher than those of people with other education levels (P < 0.05); the total score of anxiety, depression and psychological state in people with the Acute Physiological and Chronic Health Status Rating Scale (APACHE Ⅱ) score ≥ 20 were significantly higher than those with APACHE Ⅱ score < 20, and the mental state score of people with adverse events were significantly higher than those without adverse events (P < 0.05). The incidence of adverse events inpatients with APACHE Ⅱscore ≥ 20 was significantly higher than that in patients with APACHE Ⅱscore < 20 (P < 0.05). Multivariate Logistic regression model analysis showed that APACHE Ⅱscore ≥ 20 was an independent risk factor for adverse events in AOPP patients (P < 0.05); age ≥ 45 years old, APACHE Ⅱscore ≥ 20 and adverse events were independent risk factors affecting the psychological status of AOPP patients (P < 0.05).

Conclusion AOPP patients are prone to have adverse events and are accompanied by various negative psychological states. During strengthening the monitoring of the disease, the attention should be paid to the observation of psychological reactions, and it is also necessary to carry out individualized psychological intervention.