XU Xiaoya, GUO Xiaocong, WANG Mingjin, ZHAO Ling, QIU Tao, PU Yangyang. Quality of life and its influencing factors in adult epileptic patients in Zigong City of Sichuan Province[J]. Journal of Clinical Medicine in Practice, 2022, 26(20): 66-69. DOI: 10.7619/jcmp.20221793
Citation: XU Xiaoya, GUO Xiaocong, WANG Mingjin, ZHAO Ling, QIU Tao, PU Yangyang. Quality of life and its influencing factors in adult epileptic patients in Zigong City of Sichuan Province[J]. Journal of Clinical Medicine in Practice, 2022, 26(20): 66-69. DOI: 10.7619/jcmp.20221793

Quality of life and its influencing factors in adult epileptic patients in Zigong City of Sichuan Province

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  • Received Date: June 07, 2020
  • Available Online: November 03, 2022
  • Objective 

    To analyze the quality of life and its influencing factors of adult epilepsy patients in Zigong City.

    Methods 

    A total of 200 urban and rural adults with epilepsy in Zigong City Epilepsy Reporting System were randomly selected. The demographic characteristics and related clinical data of epilepsy patients were described. The quality of life of patients with epilepsy was evaluated, and the related influencing factors of the quality of life of patients with epilepsy were analyzed.

    Results 

    Among the 200 patients with epilepsy in Zigong, the proportions of males and females were 56.5% and 43.5%, respectively, and the proportion of young and middle-aged patients with epilepsy was 78.0%. Most of them were farmers or migrant workers, accounting for 62.5%, and unemployed people accounted for 22.5%. 65.0% of the patients were junior high school graduates, and 84.0% of the patients were junior high school or below. Unmarried and divorced people accounted for 34.0%; the main seizure type was generalized epilepsy, accounting for 79.0%. The mean score of quality of life of adult patients with epilepsy in Zigong City was 56.64 by Epilepsy Quality of Life Scale. Multivariate linear regression analysis showed that active epilepsy, epileptic comorbidities anxiety, depression and cognitive impairment were the adverse influencing factors of quality of life in epilepsy patients (P < 0.05).

    Conclusion 

    The quality of life of adult epileptic patients in Zigong City is relatively low. In addition to controlling epileptic seizures, the clinical treatment also needs to evaluate the anxiety, depression and cognitive impairment of epileptic comorbidity, and intervention should be given.

  • [1]
    贾建平, 崔丽英. 神经病学[M]. 北京: 人民卫生出版社, 2019: 349-650.
    [2]
    SAXENA S, LI S C. Defeating epilepsy: a global public health commitment[J]. Epilepsia Open, 2017, 2(2): 153-155. doi: 10.1002/epi4.12010
    [3]
    WU D Y, DING D, WANG Y, et al. Quality of life and related factors in Chinese adolescents with active epilepsy[J]. Epilepsy Res, 2010, 90(1/2): 16-20.
    [4]
    CHEN H F, TSAI Y F, HSI M S, et al. Factors affecting quality of life in adults with epilepsy in Taiwan: a cross-sectional, correlational study[J]. Epilepsy Behav, 2016, 58: 26-32. doi: 10.1016/j.yebeh.2016.02.019
    [5]
    SIARAVA E, HYPHANTIS T, KATSANOS A H, et al. Depression and quality of life in patients with epilepsy in Northwest Greece[J]. Seizure, 2019, 66: 93-98. doi: 10.1016/j.seizure.2019.02.012
    [6]
    刘雪琴, 任晓琳, 周谷兰, 陈平雁. 成年癫痫患者生活质量-31量表的信度和效度[J]. 中华神经医学杂志, 2003, 2(2): 106-109. doi: 10.3760/cma.j.issn.1671-8925.2003.02.013
    [7]
    王纯, 楚艳民, 张亚林, 等. 汉密尔顿焦虑量表的因素结构研究[J]. 临床精神医学杂志, 2011, 21(5): 299-301. https://www.cnki.com.cn/Article/CJFDTOTAL-LCJS201105009.htm
    [8]
    张明园. 精神科评定量表手册[M]. 长沙: 湖南科学技术出版社, 1993: 1-10.
    [9]
    LI H Z, JIA J P, YANG Z Q. Mini-mental state examination in elderly Chinese: a population-based normative study[J]. J Alzheimers Dis, 2016, 53(2): 487-496. doi: 10.3233/JAD-160119
    [10]
    岳丽, 虞培敏, 赵德豪, 等. 癫痫患者生活质量的影响因素及其年龄性别差异[J]. 中华医学杂志, 2010, 90(23): 1597-1601. doi: 10.3760/cma.j.issn.0376-2491.2010.23.004
    [11]
    HESSEN E, LOSSIUS M I, GJERSTAD L. Behavioural adjustment in seizure-free epilepsy patients on monotherapy[J]. Seizure, 2008, 17(5): 422-430. doi: 10.1016/j.seizure.2007.12.002
    [12]
    GUR-OZMEN S, LEIBETSEDER A, COCK H R, et al. Screening of anxiety and quality of life in people with epilepsy[J]. Seizure, 2017, 45: 107-113. doi: 10.1016/j.seizure.2016.11.026
    [13]
    NAGARATHNAM M, SHALINI B, VIJAYALAKSHMI V, et al. Predictors of quality of life among adolescents with epilepsy in the state of Andhra Pradesh[J]. Neurol India, 2017, 65(5): 1019-1024. doi: 10.4103/neuroindia.NI_1251_15
    [14]
    宫玉哲. 癫痫患者生活质量分析及其影响因素研究[D]. 兰州: 兰州大学, 2020.
    [15]
    RAWLINGS G H, BROWN I, REUBER M. Predictors of health-related quality of life in patients with epilepsy and psychogenic nonepileptic seizures[J]. Epilepsy Behav, 2017, 68: 153-158. doi: 10.1016/j.yebeh.2016.10.035
    [16]
    SCOTT A J, SHARPE L, HUNT C, et al. Anxiety and depressive disorders in people with epilepsy: a meta-analysis[J]. Epilepsia, 2017, 58(6): 973-982. doi: 10.1111/epi.13769
    [17]
    LI Q, CHEN D, ZHU L N, et al. Depression in people with epilepsy in West China: Status, risk factors and treatment gap[J]. Seizure, 2019, 66: 86-92. doi: 10.1016/j.seizure.2019.02.014
    [18]
    徐沛, 苏佩清, 颜丙春. 癫痫合并认知功能障碍的研究及治疗进展[J]. 中华老年心脑血管病杂志, 2018, 20(2): 216-219. doi: 10.3969/j.issn.1009-0126.2018.02.030
    [19]
    WITT J A, HELMSTAEDTER C. Cognition in the early stages of adult epilepsy[J]. Seizure, 2015, 26: 65-68. doi: 10.1016/j.seizure.2015.01.018
    [20]
    庄婵芝, 潘志雄, 何素丽, 等. 难治性癫痫患者神经调节蛋白1、microRNA-221-3p表达与认知功能的关系[J]. 实用临床医药杂志, 2021, 25(22): 50-54. doi: 10.7619/jcmp.20212229
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