Value of color Doppler ultrasound combined with coagulation indexes detection in predicting deep venous thrombosis of lower limbs after fracture

To analyze the value of color Doppler ultrasound combined with preoperative coagulation indexes detection in predicting deep venous thrombosis (DVT) of lower limbs after fracture.

From September 2019 to March 2022, 80 patients with traumatic fracture were selected and divided into DVT group (n=29) and non-DVT group (n=51) according to the incidence of DVT during hospitalization after surgery. The patients received blood coagulation test before operation and color Doppler ultrasonography after operation. The results of examinations were compared between the two groups, and the relationships of DVT with color Doppler ultrasound and coagulation indexes were analyzed.

The levels of fibrinogen (FIB) and D-dimer (D-D) in the DVT group were significantly higher than those in the non-DVT group (P < 0.05). The inner diameter, blood flow velocity and end diastolic velocity of blood vessels in the DVT group were significantly lower than those in the non-DVT group (P < 0.05). Logistic regression analysis showed that blood flow velocity, end diastolic velocity, FIB and D-D were the influencing factors of postoperative DVT during hospitalization in patients with fracture (P < 0.05). The area under the curve (AUC) of blood flow velocity, end diastolic velocity, FIB and D-D levels in predicting the occurrence of DVT independently in fracture patients during hospitalization after surgery were 0.781, 0.720, 0.753 and 0.705 respectively, and the AUC of combination of the four indicators was 0.952.

The increase of FIB and D-D levels before operation and the decrease of blood flow velocity and end diastolic velocity after operation are the risk factors of DVT in fracture patients during hospitalization after operation, and the combination of four indicators has the certain clinical reference value in predicting DVT in fracture patients during hospitalization after operation.