Correlations between TCM syndromes and clinical factors after colorectal cancer surgery

Objective To explore the correlations of TCM syndromes with age, gender, differentiation degree and stage of colon cancer patients after surgery.

Methods A total of 351 patients with colorectal cancer after surgery in the Anorectal Center of Tianjin People′s Hospital were recruited in the study.The clinical data, symptoms and signs of the patients were collected to analyze the correlations of TCM syndromes after surgery with age, gender, degree of differentiation, stage and other factors.

Results The postoperative TCM syndromes of colorectal cancer included spleen-kidney deficiency, liver-kidney Yin deficiency, spleen deficiency and qi stagnation, liver-spleen dysregulation, and qi and blood deficiency.Age, gender, stage were correlated with the distribution of TCM syndromes (P < 0.05).There was no correlation between differentiation degree and TCM syndromes (P>0.05). Multivariate Logistic regression analysis showed that age and gender were two independent factors affecting dual deficiency of spleen and kidney, clinical stage and patient′s age can be regarded as independent factors in patients with liver and kidney Yin deficiency syndrome, and clinical stage can be regarded as an independent factor in patients with spleen deficiency and Qi stagnation syndrome.

Conclusion After colorectal cancer surgery, the main clinical TCM syndromes are spleen-kidney deficiency, liver-kidney yin deficiency, spleen deficiency and qi stagnation. TCM syndrome is correlated with age, gender and clinical stage. Selecting appropriate TCM adjuvant therapy according to different postoperative syndromes can not only improve the immune function of patients, but also relieve the adverse reactions caused by radiotherapy and chemotherapy.