WANG Zhijian, CHENG Lai, SHEN Xueqin. Effects of prepregnancy weight, gestational weight gain and other related factors on antepartum depression[J]. Journal of Clinical Medicine in Practice, 2023, 27(11): 49-54. DOI: 10.7619/jcmp.20223593
Citation: WANG Zhijian, CHENG Lai, SHEN Xueqin. Effects of prepregnancy weight, gestational weight gain and other related factors on antepartum depression[J]. Journal of Clinical Medicine in Practice, 2023, 27(11): 49-54. DOI: 10.7619/jcmp.20223593

Effects of prepregnancy weight, gestational weight gain and other related factors on antepartum depression

More Information
  • Received Date: December 01, 2022
  • Revised Date: March 29, 2023
  • Available Online: June 24, 2023
  • Objective 

    To explore the effects of pre-pregnancy weight, gestational weight gain(GWG) and other relevant factors on antepartum depression.

    Methods 

    A total of 559 singleton pregnant women were selected as research objects. According to the pre-pregnancy body mass index (BMI), the pre-pregnancy body mass was divided into pre-pregnancy underweight (BMI < 18.5 kg/m2), normal body weight (BMI 18.5 to 25 kg/m2) and overweight/obese (BMI≥25.0 kg/m2). Further according to the GWG recommended value by the Institute of Medicine (IOM), GWG were divided into insufficient GWG, appropriate GWG and excessive GWG. The correlations of pre-pregnancy weight, GWG and other related factors with pre-pregnancy score of Edinburgh Postnatal Depression Scale (EPDS) were analyzed.

    Results 

    Among 559 pregnant women, there were 54 cases (9.7%) of low body weight before pregnancy, 427 cases (76.4%) of normal body weight, 78 cases (13.9%) of overweight/obese, 96 cases (17.2%) of insufficient GWG, 191 cases (34.2%) of appropriate GWG, 272 cases (48.7%) of excessive GWG. 65.4% (51/78) of overweight/obese pregnant women had excessive GWG before pregnancy. Single factor analysis results showed that there were significant differences in pre-pregnancy EPDS score among underweight, normal weight and overweight/obese pregnant women (P=0.035). There was no significant difference in pre-pregnancy EPDS among pregnant women with insufficient GWG, appropriate GWG and excessive GWG (P=0.388). There were significant differences in pre-pregnancy EPDS scores among pregnant women with different quality of life satisfaction and different pregnancy intention(P=0.002, P=0.005). Multiple linear regression analysis results showed that pregnancy intention, quality of life satisfaction, parity, overweight/obesity were influencing factors of pre-pregnancy EPDS score(P < 0.05). Pre-pregnancy EPDS score was negatively correlated with pregnancy intention, quality of life satisfaction and parity, and was positively correlated with overweight/obesity before pregnancy.

    Conclusion 

    Pre-pregnancy body mass, pregnancy intention, satisfaction of quality of life, and delivery time are the influencing factors of pre-pregnancy depression, while GWG has no correlation with pre-pregnancy depression. Prevention of depression during pregnancy in overweight/obese women should focus on intervention of overweight/obesity before pregnancy. In the perinatal health care work, medical staff should pay attention to the psychological state of pregnant women with unwanted pregnancy and low satisfaction of life quality, thereby improving their pregnancy outcome.

  • [1]
    赵欣, 杨慧霞. 超重/肥胖女性孕期增重过多对妊娠结局及子代远期健康影响的研究进展[J]. 中华围产医学杂志, 2020, 23(9): 640-644. doi: 10.3760/cma.j.cn113903-20200114-00022
    [2]
    INSAN N, SLACK E, HESLEHURST N, et al. Antepartum depression and anxiety and early pregnancy BMI among White British and South Asian women: retrospective analysis of data from the Born in Bradford cohort[J]. BMC Pregnancy Childbirth, 2020, 20(1): 502. doi: 10.1186/s12884-020-03097-2
    [3]
    US Preventive Services Task Force, CURRY S J, KRIST A H, et al. Interventions to prevent perinatal depression: us preventive services task force recommendation statement[J]. JAMA, 2019, 321(6): 580-587. doi: 10.1001/jama.2019.0007
    [4]
    中华医学会妇产科学分会产科学组. 围产期抑郁症筛查与诊治专家共识[J]. 中华妇产科杂志, 2021, 56(8): 521-527. doi: 10.3760/cma.j.cn112141-20210115-00022
    [5]
    LEVIS B, NEGERI Z, SUN Y, et al. Accuracy of the Edinburgh Postnatal Depression Scale (EPDS) for screening to detect major depression among pregnant and postpartum women: systematic review and meta-analysis of individual participant data[J]. BMJ, 2020, 371: m4022.
    [6]
    陈秀云, 毕清泉, 张凤凤, 等. 本科护生心理健康双因素模型的构建[J]. 中华现代护理杂志, 2020, 26(26): 3686-3690. doi: 10.3760/cma.j.cn115682-20200421-02897
    [7]
    EICK S M, WELTON M, CLARIDY M D, et al. Associations between gestational weight gain and preterm birth in Puerto Rico[J]. BMC Pregnancy Childbirth, 2020, 20(1): 599. doi: 10.1186/s12884-020-03292-1
    [8]
    Institute of Medicine (US) and National Research Council (US) Committee to Reexamine IOM Pregnancy Weight Guidelines. Weight Gain During Pregnancy: Reexamining the Guidelines[M]. Washington(DC): National Academies Press(US), 2009: 15-25
    [9]
    TRAYLOR C S, JOHNSON J D, KIMMEL M C, et al. Effects of psychological stress on adverse pregnancy outcomes and nonpharmacologic approaches for reduction: an expert review[J]. Am J Obstet Gynecol MFM, 2020, 2(4): 100229. doi: 10.1016/j.ajogmf.2020.100229
    [10]
    张笑童, 刘珏, 刘民, 等. 妇女孕期睡眠障碍与焦虑及抑郁状态关系的研究[J]. 中国预防医学杂志, 2021, 22(1): 17-22. doi: 10.16506/j.1009-6639.2021.01.004
    [11]
    BARRETT E S, VITEK W, MBOWE O, et al. Allostatic load, a measure of chronic physiological stress, is associated with pregnancy outcomes, but not fertility, among women with unexplained infertility[J]. Hum Reprod, 2018, 33(9): 1757-1766. doi: 10.1093/humrep/dey261
    [12]
    修青永, 王蕊, 鲍玲, 等. 母亲中、晚孕期焦虑/抑郁心理状况对婴儿早期气质的影响[J]. 中华围产医学杂志, 2020, 23(12): 793-800. doi: 10.3760/cma.j.cn113903-20200312-00232
    [13]
    BLAU L E, HORMES J M. Preventing excess gestational weight gain and obesity in pregnancy: the potential of targeting psychological mechanisms[J]. Curr Obes Rep, 2020, 9(4): 522-529. doi: 10.1007/s13679-020-00415-9
    [14]
    KUMPULAINEN S M, GIRCHENKO P, LAHTI-PULKKINEN M, et al. Maternal early pregnancy obesity and depressive symptoms during and after pregnancy[J]. Psychol Med, 2018, 48(14): 2353-2363. doi: 10.1017/S0033291717003889
    [15]
    DACHEW B A, AYANO G, BETTS K, et al. The impact of pre-pregnancy BMI on maternal depressive and anxiety symptoms during pregnancy and the postpartum period: a systematic review and meta-analysis[J]. J Affect Disord, 2021, 281: 321-330. doi: 10.1016/j.jad.2020.12.010
    [16]
    ERTEL K A, HUANG T Y, RIFAS-SHIMAN S L, et al. Perinatal weight and risk of prenatal and postpartum depressive symptoms[J]. Ann Epidemiol, 2017, 27(11): 695-700. doi: 10.1016/j.annepidem.2017.10.007
    [17]
    吴金华, 张友定, 姜雯, 等. 孕产妇产前抑郁与妊娠期体重增加的关系[J]. 疾病监测, 2016, 31(9): 781-785. https://www.cnki.com.cn/Article/CJFDTOTAL-JBJC201609015.htm
    [18]
    王媺媞, 崔东红. 抑郁症与肥胖共病的研究进展[J]. 临床精神医学杂志, 2016, 26(2): 134-135. https://www.cnki.com.cn/Article/CJFDTOTAL-LCJS201602031.htm
    [19]
    HOLTON S, FISHER J, NGUYEN H, et al. Pre-pregnancy body mass index and the risk of antepartum depression and anxiety[J]. Women Birth, 2019, 32(6): e508-e514. doi: 10.1016/j.wombi.2019.01.007
    [20]
    尤优, 严双琴, 黄锟, 等. 妊娠意愿与孕中晚期妊娠相关焦虑关联的队列研究[J]. 中华流行病学杂志, 2017, 38(9): 1179-1182. doi: 10.3760/cma.j.issn.0254-6450.2017.09.007
    [21]
    EICHLER J, SCHMIDT R, HIEMISCH A, et al. Gestational weight gain, physical activity, sleep problems, substance use, and food intake as proximal risk factors of stress and depressive symptoms during pregnancy[J]. BMC Pregnancy Childbirth, 2019, 19(1): 175. doi: 10.1186/s12884-019-2328-1
    [22]
    SURKAN P J, STROBINO D M, MEHRA S, et al. Unintended pregnancy is a risk factor for depressive symptoms among socio-economically disadvantaged women in rural Bangladesh[J]. BMC Pregnancy Childbirth, 2018, 18(1): 490. doi: 10.1186/s12884-018-2097-2
    [23]
    HALL K S, KUSUNOKI Y, GATNY H, et al. Social discrimination, stress, and risk of unintended pregnancy among young women[J]. J Adolesc Health, 2015, 56(3): 330-337. doi: 10.1016/j.jadohealth.2014.11.008
    [24]
    刘文婷, 陈瑜, 陶艳玲, 等. 初产妇和经产妇产前抑郁情绪的影响因素研究[J]. 解放军护理杂志, 2022, 39(7): 1-4. https://www.cnki.com.cn/Article/CJFDTOTAL-JFHL202207001.htm
    [25]
    JEONG H G, LIM J S, LEE M S, et al. The association of psychosocial factors and obstetric history with depression in pregnant women: focus on the role of emotional support[J]. Gen Hosp Psychiatry, 2013, 35(4): 354-358. doi: 10.1016/j.genhosppsych.2013.02.009
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