Objective To investigate the influence of patient-related factors on hospital-home medication discrepancy in patients with chronic heart failure (CHF) during the transitional period (short for transitional period).
Methods A total of 405 patients with CHF in the transitional period were randomly selected by convenient sampling method. A telephone follow-up study was conducted using questionnaires, including the general information questionnaire, Medication Discrepancy Tool, Morisky Medication Adherence Scale (MMAS), Self-efficacy for Appropriate Medication Use Scale (SEAMS), and medication literacy questionnaire. The influence of patient-related factors on transitional medication discrepancy was analyzed by Logistic regression.
Results Among 405 patients, 270 had transitional medication discrepancy, with an incidence of 66.67%. The univariate analysis showed that there were statistically significant differences between the group with medication discrepancy and the group without in terms of heart failure duration, MMAS score, SEAMS score, and medication literacy score (P < 0.05). Binary Logistic regression analysis showed that high scores in MMAS, SEAMS and medication literacy were independent protective factors for transtional medication discrepancy in CHF patients (OR=0.241, 0.922, 0.541, P < 0.05), and the MMAS score had the strongest association.
Conclusion MMAS, SEAMS and medication literacy scores in patients with CHF are the influencing factors of medication discrepancy in the period of transition, suggesting the need for comprehensive assessment and targeted intervention strategies before discharge to reduce transitional medication discrepancy.
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