SU Ziwen, WANG Weiyun, XU Dongmei, LIU Changhong, ZHOU Ruhua, YANG Lei, GU Zejuan. Influence of patient-related factors on medication discrepancy during hospital-home transition in patients with chronic heart failure[J]. Journal of Clinical Medicine in Practice, 2023, 27(7): 78-83. DOI: 10.7619/jcmp.20223602
Citation: SU Ziwen, WANG Weiyun, XU Dongmei, LIU Changhong, ZHOU Ruhua, YANG Lei, GU Zejuan. Influence of patient-related factors on medication discrepancy during hospital-home transition in patients with chronic heart failure[J]. Journal of Clinical Medicine in Practice, 2023, 27(7): 78-83. DOI: 10.7619/jcmp.20223602

Influence of patient-related factors on medication discrepancy during hospital-home transition in patients with chronic heart failure

More Information
  • Received Date: December 02, 2022
  • Revised Date: March 25, 2023
  • Available Online: April 22, 2023
  • Objective 

    To investigate the influence of patient-related factors on hospital-home medication discrepancy in patients with chronic heart failure (CHF) during the transitional period (short for transitional period).

    Methods 

    A total of 405 patients with CHF in the transitional period were randomly selected by convenient sampling method. A telephone follow-up study was conducted using questionnaires, including the general information questionnaire, Medication Discrepancy Tool, Morisky Medication Adherence Scale (MMAS), Self-efficacy for Appropriate Medication Use Scale (SEAMS), and medication literacy questionnaire. The influence of patient-related factors on transitional medication discrepancy was analyzed by Logistic regression.

    Results 

    Among 405 patients, 270 had transitional medication discrepancy, with an incidence of 66.67%. The univariate analysis showed that there were statistically significant differences between the group with medication discrepancy and the group without in terms of heart failure duration, MMAS score, SEAMS score, and medication literacy score (P < 0.05). Binary Logistic regression analysis showed that high scores in MMAS, SEAMS and medication literacy were independent protective factors for transtional medication discrepancy in CHF patients (OR=0.241, 0.922, 0.541, P < 0.05), and the MMAS score had the strongest association.

    Conclusion 

    MMAS, SEAMS and medication literacy scores in patients with CHF are the influencing factors of medication discrepancy in the period of transition, suggesting the need for comprehensive assessment and targeted intervention strategies before discharge to reduce transitional medication discrepancy.

  • [1]
    COLEMAN E A, SMITH J D, RAHA D, et al. Posthospital medication discrepancies: prevalence and contributing factors[J]. Arch Intern Med, 2005, 165(16): 1842-1847. doi: 10.1001/archinte.165.16.1842
    [2]
    GIANNINI O, RIZZA N, PIRONI M, et al. Prevalence, clinical relevance and predictive factors of medication discrepancies revealed by medication reconciliation at hospital admission: prospective study in a Swiss internal medicine ward[J]. BMJ Open, 2019, 9(5): e026259. doi: 10.1136/bmjopen-2018-026259
    [3]
    NAYLOR M D, MARCILLE J. Managing the transition from the hospital[J]. Manag Care, 2014, 23(6): 27-30.
    [4]
    MOGHLI M A, FARHA R A, HAMMOUR K A. Medication discrepancies in hospitalized cancer patients: do we need medication reconciliation[J]. J Oncol Pharm Pract, 2021, 27(5): 1139-1146. doi: 10.1177/1078155220946388
    [5]
    潘凌蕴. 老年慢性肾脏病患者医院: 家庭过渡期用药偏差的发生情况及相关因素研究[D]. 南京: 南京大学, 2018.
    [6]
    马园华. 老年骨质疏松性骨折患者医院-家庭过渡期用药偏差的相关因素分析[D]. 湖州: 湖州师范学院, 2021.
    [7]
    国家卫生计生委合理用药专家委员会, 中国药师协会. 心力衰竭合理用药指南(第2版)[J]. 中国医学前沿杂志: 电子版, 2019, 11(7): 1-78. https://www.cnki.com.cn/Article/CJFDTOTAL-YXQY201907001.htm
    [8]
    SCHULZ M, GRIESE-MAMMEN N, ANKER S D, et al. Pharmacy-based interdisciplinary intervention for patients with chronic heart failure: results of the PHARM-CHF randomized controlled trial[J]. Eur J Heart Fail, 2019, 21(8): 1012-1021. doi: 10.1002/ejhf.1503
    [9]
    陈芳辉, 于爱晨, 傅孟元, 等. 县级医院慢性病老年患者出院带药用药偏差现状及影响因素分析[J]. 中国医院药学杂志, 2022, 42(15): 1563-1567. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYZ202215011.htm
    [10]
    常陆, 蒋梦蝶, 王梦莹, 等. 老年糖尿病患者医院-家庭过渡期用药偏差的影响因素[J]. 中华老年医学杂志, 2022, 41(4): 433-437. https://cdmd.cnki.com.cn/Article/CDMD-10730-1020654866.htm
    [11]
    SMITH J D, COLEMAN E A, MIN S J. A new tool for identifying discrepancies in postacute medications for community-dwelling older adults[J]. Am J Geriatr Pharmacother, 2004, 2(2): 141-147. doi: 10.1016/S1543-5946(04)90019-0
    [12]
    王秀英, 李英华, 肖锟婷, 等. 改良版用药差异评估工具的信度与效度评价[J]. 中国药房, 2015, 26(31): 4460-4462. doi: 10.6039/j.issn.1001-0408.2015.31.45
    [13]
    MORISKY D E, ANG A, KROUSEL-WOOD M, et al. Predictive validity of a medication adherence measure in an outpatient setting[J]. J Clin Hypertens (Greenwich), 2008, 10(5): 348-354. doi: 10.1111/j.1751-7176.2008.07572.x
    [14]
    RISSER J, JACOBSON T A, KRIPALANI S. Development and psychometric evaluation of the Self-efficacy for Appropriate Medication Use Scale (SEAMS) in low-literacy patients with chronic disease[J]. J Nurs Meas, 2007, 15(3): 203-219. doi: 10.1891/106137407783095757
    [15]
    董小方, 刘延锦, 王爱霞. 合理用药自我效能量表的汉化及信效度检验[J]. 护理学杂志, 2015, 30(11): 47-49. https://www.cnki.com.cn/Article/CJFDTOTAL-HLXZ201511018.htm
    [16]
    MANIACI M J, HECKMAN M G, DAWSON N L. Functional health literacy and understanding of medications at discharge[J]. Mayo Clin Proc, 2008, 83(5): 554-558. doi: 10.1016/S0025-6196(11)60728-3
    [17]
    郑凤, 丁四清, 钟竹青, 等. 冠状动脉内支架植入术后出院病人药物素养现状调查[J]. 护理研究, 2015, 29(14): 1732-1734. https://www.cnki.com.cn/Article/CJFDTOTAL-SXHZ201514027.htm
    [18]
    薛文俊, 牛晓丹, 王艳红. 老年2型糖尿病患者医院-家庭过渡期用药偏差的调查研究[J]. 中华护理杂志, 2021, 56(2): 225-232. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHHL202102017.htm
    [19]
    UNNI E, SUN B E. Exploring a new theoretical model to explain the behavior of medication adherence[J]. Pharmacy (Basel), 2022, 10(2): 43.
    [20]
    WU J B, TAO Z J, SONG Z J, et al. Validation and psychometric properties of the self-efficacy for Appropriate Medication Use Scale in elderly Chinese patients[J]. Int J Clin Pharm, 2021, 43(3): 586-594.
    [21]
    牛晓丹. 服药查对在老年2型糖尿病患者医院-家庭过渡期用药偏差中的应用研究[D]. 兰州: 兰州大学, 2021.
    [22]
    NEIVA PANTUZZA L L, NASCIMENTO E D, CREPALDE-RIBEIRO K, et al. Medication literacy: a conceptual model[J]. Res Social Adm Pharm, 2022, 18(4): 2675-2682.
    [23]
    GENTIZON J, BOVET E, RAPP E, et al. Medication literacy in hospitalized older adults: concept development[J]. Health Lit Res Pract, 2022, 6(2): e70-e83.
    [24]
    OZAVCI G, BUCKNALL T, WOODWARD-KRON R, et al. A systematic review of older patients' experiences and perceptions of communication about managing medication across transitions of care[J]. Res Social Adm Pharm, 2021, 17(2): 273-291.
  • Related Articles

    [1]PANG Ting, WU Weili, YANG Binjiao. Pathogen status, risk factors and prediction model construction for catheter-related infection in patients with maintenance hemodialysis[J]. Journal of Clinical Medicine in Practice, 2024, 28(21): 60-65. DOI: 10.7619/jcmp.20243000
    [2]WANG Lu, ZHAO Qimei, XIE He'nan, CHANG Lu, XIE Zheng. Status of medication deviation in hospital-home transition period in elderly patients with chronic heart failure and its influencing factors[J]. Journal of Clinical Medicine in Practice, 2024, 28(9): 109-114. DOI: 10.7619/jcmp.20233715
    [3]WANG Daoxin, LIU Nan, SHI Zeyuan, CHEN Yan, GUAN Ningxiao, ZHAO Wenli. Status quo and risk factors of medical viscose-related skin injury in severe patients: a meta-analysis[J]. Journal of Clinical Medicine in Practice, 2022, 26(22): 1-6, 11. DOI: 10.7619/jcmp.20222806
    [4]CHEN Liping, FU Jiaozhu, YUAN Dan, LIN Miaochun. Effect of information-motivation-behavioral skills model on medication compliance of patients with chronic heart failure[J]. Journal of Clinical Medicine in Practice, 2018, (14): 8-10,15. DOI: 10.7619/jcmp.201814003
    [5]YU Daling, LIU Min, JIA Zhe. Application of hospital-home care model in the elderly discharged patients with diabetes[J]. Journal of Clinical Medicine in Practice, 2017, (12): 147-149. DOI: 10.7619/jcmp.201712046
    [6]CHEN Mo. Change of plasma Ghrelin level in patients with hyperthyroidism and its related factors[J]. Journal of Clinical Medicine in Practice, 2016, (5): 67-69. DOI: 10.7619/jcmp.201605020
    [7]MA Qunhua. Infection factors in emergency nursing of critically ill patients with trauma and its countermeasures[J]. Journal of Clinical Medicine in Practice, 2015, (14): 62-64. DOI: 10.7619/jcmp.201514020
    [8]SONG Juan, WANG Xuemei. Analysis on related factors of incontinence-associated dermatitis in hospitalized patients[J]. Journal of Clinical Medicine in Practice, 2014, (20): 77-80. DOI: 10.7619/jcmp.201420024
    [9]ZHU Mingrong, GAO Jie. Effect of behavioral therapy on medication compliance in recovery period for hospitalized psychopathic patients[J]. Journal of Clinical Medicine in Practice, 2014, (14): 48-50. DOI: 10.7619/jcmp.201414016
    [10]CHEN Yangxia. Related factors and preventive measures of patients with intraoperative acute pressure sores[J]. Journal of Clinical Medicine in Practice, 2014, (4): 92-94. DOI: 10.7619/jcmp.201404034
  • Cited by

    Periodical cited type(3)

    1. 贾庶捷,张倩落,李燕平,任健,杨海敏. 血必净注射液联合连续性肾替代疗法、白蛋白治疗肾综合征出血热的效果及对炎性因子、相关蛋白表达的影响. 临床医学研究与实践. 2024(02): 58-61 .
    2. 姜文娟,贺芬,任阳,张旭. 血清清蛋白联合动态动脉僵硬指数对急性缺血性脑卒中病人静脉溶栓后出血转化的预测价值. 中西医结合心脑血管病杂志. 2023(05): 908-912 .
    3. 饶建锋,李珊. 流行性出血热患者血清CK-MB、IL-6、IL-10水平与病情程度、预后的关系研究. 中国医学创新. 2023(27): 137-141 .

    Other cited types(1)

Catalog

    Article views (126) PDF downloads (8) Cited by(4)

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return