Citation: | LIU Guixiang, AN Jinmei, HOU Jichong, SONG Nuan, ZHAO Yuexia. Effects of painting combined with drug intervention on mental states, compliance and quality of life in patients with anxiety disorder[J]. Journal of Clinical Medicine in Practice, 2023, 27(22): 81-85. DOI: 10.7619/jcmp.20230109 |
To analyze the effects of painting and medication intervention on psychological state, compliance and quality of life in patients with generalized anxiety disorder (GAD).
A total of 70 patients with GAD from May 2020 to September 2022 were included as study subjects, among whom 35 patients receiving single drug intervention were included in single group, and 35 patients receiving painting combined drug intervention were included in combined group. The psychological state scores and intervention compliance of the subjects in the two groups were analyzed, the life quality scores and serum factor expression levels of the subjects in the two groups were compared before and after intervention, and the changes in sleep quality of the two groups were observed before and after intervention.
After intervention, the scores of Hamilton Anxiety Rating Scale (HAMA), Hamilton Depression Rating Scale (HAMD) in the two groups were decreased compared with those before intervention, but their scores in the combined group were lower, and the differences were statistically significant (P < 0.05). The total compliance rate of the combined group was higher than that of the single group (P < 0.05). After intervention, the 36-item Shot-form Health Status Survey (SF-36) scores of the two groups were improved compared with that before intervention, and the SF-36 score of the combined group was higher, the difference was statistically significant (P < 0.05). After intervention, the expression levels of brain derived neurotrophic factor (BDNF) and malondialdehyde (MDA) in the combined group were lower than those in the single group, and the expression level of superoxide dismutase (SOD) was higher than those in the single group (P < 0.05). After intervention, the sleep quality of the two groups was improved compared with that before intervention, but the improvement degree of the combined group was higher (P < 0.05).
Painting combined with drug intervention can effectively improve the adverse psychological state of GAD patients, improve their intervention compliance, and further improve their quality of life and sleep quality.
[1] |
倪照军, 栗雪琪, 黄薛冰. 团体正念认知治疗对广泛性焦虑障碍患者的焦虑和注意维持的疗效[J]. 中国心理卫生杂志, 2022, 36(5): 361-366. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXWS202205001.htm
|
[2] |
CHENG Y C, SU M I, LIU C W, et al. Heart rate variability in patients with anxiety disorders: A systematic review and meta-analysis[J]. Psychiatry Clin Neurosci, 2022, 76(7): 292-302. doi: 10.1111/pcn.13356
|
[3] |
STRAARUP N S, RENNEBERG H B, FARRELL J, et al. Group schema therapy for patients with severe anxiety disorders[J]. J Clin Psychol, 2022, 78(8): 1590-1600.
|
[4] |
李云, 李菊芳, 余思思, 等. 基于焦虑认同联合优势内容递增理论的护理干预在广泛性焦虑障碍患者中的应用[J]. 中华现代护理杂志, 2022, 28(4): 544-547.
|
[5] |
胡丽平, 周波, 杨俊华. 焦虑障碍患者正念任务态下的心率变异性研究[J]. 实用医院临床杂志, 2022, 19(2): 100-104. https://www.cnki.com.cn/Article/CJFDTOTAL-YYLC202202028.htm
|
[6] |
谢远丝, 张慧, 姚慧慧. 短程认知行为疗法联合药物治疗焦虑障碍的临床研究[J]. 海南医学, 2022, 33(9): 1145-1147. https://www.cnki.com.cn/Article/CJFDTOTAL-HAIN202209015.htm
|
[7] |
BERGER M, LI E, RICE S, et al. Cannabidiol for Treatment-Resistant Anxiety Disorders in Young People: An Open-Label Trial[J]. J Clin Psychiatry, 2022, 83(5): 14130.
|
[8] |
程苗苗, 郭晓岚, 卫攀, 等. 曼陀罗绘画疗法在经皮冠状动脉介入术后患者中的应用及效果观察[J]. 护士进修杂志, 2021, 36(16): 1496-1500. https://www.cnki.com.cn/Article/CJFDTOTAL-FSJX202116013.htm
|
[9] |
马娟. 国际疾病分类(ICD-10)电子辞典[J]. 中国病案, 2000, 1(1): 29-33. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGBN2000S1013.htm
|
[10] |
冯霞, 叶欣, 舒慧玲, 等. 患者健康问卷抑郁量表 9在痤疮患者中的信度和效度检验[J]. 中华皮肤科杂志, 2019, 52(7): 461-466. https://cdmd.cnki.com.cn/Article/CDMD-12121-1023007520.htm
|
[11] |
叶瑞繁, 耿庆山, 陈剑, 等. 3种焦虑评定量表在综合医院门诊患者中的应用比较[J]. 中华行为医学与脑科学杂志, 2013(3): 271-273.
|
[12] |
SHARIFI F, SAFIZADEH H, BAHRAMPOUR A. Development of the Quality of Life Questionnaire (SF-36) for Patients with β-Thalassemia Major and β-Thalassemia Intermedia Based on Extended Rasch Analysis[J]. Hemoglobin, 2021, 45(2): 119-123.
|
[13] |
FOMICHEVA A V, TROSHINA D V, SIMONOV A N, et al. Impact of anxiety disorders on adherence to anticoagulant therapy in patients with atrial fibrillation[J]. Ter Arkh, 2022, 94(9): 1085-1093.
|
[14] |
梁军利, 唐士婷, 梁津瑜, 等. 加巴喷丁联合西酞普兰滴定治疗慢性偏头痛伴广泛性焦虑障碍临床疗效分析[J]. 中国医院药学杂志, 2021, 41(11): 1131-1136. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYZ202111010.htm
|
[15] |
安金媚, 张鹤卿, 刘贵香, 等. 绘画联合药物干预对焦虑障碍患者的治疗效果[J]. 实用临床医药杂志, 2022, 26(20): 40-44. doi: 10.7619/jcmp.20221995
|
[16] |
高烽宸, 彭凡, 罗伟, 等. 药物联合曼陀罗绘画治疗抑郁障碍的效果分析[J]. 成都医学院学报, 2020, 15(6): 748-751, 762. https://www.cnki.com.cn/Article/CJFDTOTAL-CDYU202006017.htm
|
[17] |
ZHOU S, WEI L, WANG Z, et al. Effect of painting intervention based on Mandala-self theory on mood and physiological state in patients in preoperative waiting room[J]. Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2021, 46(3): 293-299.
|
[18] |
董爱红, 鲁晶颖, 南喜雀. 曼陀罗彩绘对康复期精神分裂症患者焦虑抑郁情绪的影响[J]. 国际精神病学杂志, 2021, 48(5): 822-824. https://www.cnki.com.cn/Article/CJFDTOTAL-GWYJ202105015.htm
|
[19] |
李良, 戴雄凯, 曾雷. 药物治疗联合绘画治疗对抑郁症患者康复效果的影响[J]. 临床精神医学杂志, 2022, 32(2): 147-149. https://www.cnki.com.cn/Article/CJFDTOTAL-LCJS202202018.htm
|