Research progress of traditional Chinese medicine in the treatment of gouty arthritis
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Graphical Abstract
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Abstract
Gouty arthritis is a common metabolic rheumatism, with main clinical manifestations of redness, swelling, heat pain and dysfunction of the affected joints. At this stage, there are many ways to treat gout with Chinese medicine, and the curative effect is accurate and the side effects are less than western medicine. In clinical practice, traditional Chinese medicine is commonly used in the treatment of gouty arthritis, sucha as oral administration, external application of traditional Chinese medicine, acupuncture and other therapies, the combined use of these methods is better. Experimental studies have shown that the treatment mechanism of gout by traditional Chinese medicine is closely related to regulating purine metabolism, lowering blood uric acid, lowering inflammatory factor levels, regulating cell apoptosis and mitochondrial autophagy, improving antioxidant stress and regulating intestinal flora and so on. These research results are of great significance to further explore the effective active ingredients and molecular mechanisms of Chinese medicine in the treatment of gouty arthritis. This article reviewed the treatment of gouty arthritis by Chinese medicine from experimental research and clinical application, in order to further clarify the mechanism of Chinese medicine in the treatment of gout and provide new ideas for clinical diagnosis and treatment.
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