| Citation: |
JI Wenxia, WANG Ran, HUANG Qing, LI Jie. Clinical analysis of transnasal endoscopic low temperature plasma radiofrequency ablation in treatment of children with snoring[J]. Journal of Clinical Medicine in Practice, 2023, 27(24): 77-81. DOI: 10.7619/jcmp.20231355
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To explore the efficacy and postoperative complications of transnasal endoscopic low temperature plasma radiofrequency ablation in the treatment of children with snoring.
Clinical materials of 278 children with snoring were analyzed retrospectively, and they were divided into control group (n=128) and observation group (n=150) according to different operation methods. The control group was treated with adenoidectomy and bilateral tonsillectomy, while the observation group was treated with transnasal endoscopic low temperature plasma radiofrequency ablation. Perioperative indicators, the Visual Analogue Scale (VAS) score, inflammatory factors [tumor necrosis factor-α (TNF-α), interleukin-4 (IL-4) and interleukin-8 (IL-8)], stress response indicators [malondialdehyde (MDA), superoxide dismutase (SOD) and glutathione (GSH)], ventilation function indicators [apnea hyponea index (AHI), oxygen desaturation index (ODI), the longest apnea time (LAT) and nocturnal lowest blood oxygen saturation (LSaO2)], the Pittsburgh Sleep Quality Index (PSQI) score and the incidence of complications were compared between the two groups.
In the observation group, the operation time, symptom relief time and hospital stay were significantly shorter than those in the control group, while the intraoperative bleeding volume was significantly less than that in the control group (P<0.05). The VAS scores of the observation group at 6, 24, 48 and 72 h after operation were significantly lower than those of the control group (P<0.05). At 3 days after operation, serum TNF-α, IL-4 and IL-8 levels in the observation group were significantly lower than those in the control group (P<0.05); at 24 hours after operation, serum MDA level in the observation group was significantly lower than that in the control group, while the levels of SOD and GSH were significantly higher than those in the control group (P<0.05); at 6 months after operation, AHI, ODI and LAT in the observation group were significantly lower than those in the control group, while the LSaO2 was significantly higher than that in the control group (P<0.05); at 6 months after surgery, the PSQI score and incidence of complications in the observation group were significantly lower than those in the control group (P<0.05).
Transnasal endoscopic low temperature plasma radiofrequency ablation can reduce the levels of inflammatory factors, alleviate stress response, improve ventilation function, improve quality of sleep in children with snoring, and its safety is relatively high.
| [1] |
张莹, 王建波, 陈建东, 等. 低温盐水冲洗等离子腺样体切除治疗小儿鼾症的疗效和安全性观察[J]. 北京医学, 2020, 42(11): 1107-1110.
|
| [2] |
HUANG H, ZHANG L, ZHANG Q, et al. Comparison of the efficacy of two surgical procedures on adenoidal hypertrophy in children[J]. Arch Pediatr, 2020, 27(2): 72-78. doi: 10.1016/j.arcped.2019.11.010
|
| [3] |
朱敬, 顾兴华, 李亚波, 等. 鼻内镜下低温等离子技术治疗儿童睡眠呼吸暂停低通气综合征的效果观察[J]. 实用临床医药杂志, 2020, 24(24): 47-49. doi: 10.7619/jcmp.202024014
|
| [4] |
李雯, 郝中平, 王成, 等. 低温等离子腺样体切除联合双侧扁桃体方案治疗儿童鼾症的疗效及其影响因素研究[J]. 河北医科大学学报, 2022, 43(6): 688-692, 715.
|
| [5] |
丁云峰, 孙源, 王祥明, 等. 布地奈德联合孟鲁司特辅助低温等离子射频消融术治疗小儿鼾症的疗效[J]. 儿科药学杂志, 2022, 28(3): 49-52.
|
| [6] |
张丽芳, 张学强, 秦君. 低温等离子消融术对OSAHS儿童免疫功能的影响[J]. 宁夏医科大学学报, 2019, 41(2): 186-188.
|
| [7] |
《诸福棠实用儿科学》第8版书讯[J]. 临床儿科杂志, 2015, 33(4): 308.
|
| [8] |
严广斌. 视觉模拟评分法[J]. 中华关节外科杂志: 电子版, 2014, 8(2): 273.
|
| [9] |
路桃影, 李艳, 夏萍, 等. 匹兹堡睡眠质量指数的信度及效度分析[J]. 重庆医学, 2014, 43(3): 260-263.
|
| [10] |
LEE C H, HSU W C, KO J Y, et al. Adenotonsillectomy for the treatment of obstructive sleep apnea in children with prader-willi syndrome: a meta-analysis[J]. Otolaryngol Head Neck Surg, 2020, 162(2): 168-176. doi: 10.1177/0194599819893115
|
| [11] |
WANG X Y, LIU Y H, TANG G L, et al. Effects of low-temperature plasma treatment on pulmonary function in children with obstructive sleep apnea-hypopnea syndrome[J]. Ir J Med Sci, 2020, 189(2): 603-609. doi: 10.1007/s11845-019-02132-2
|
| [12] |
CAVALIERE M, LUCA P D, BONIS E D, et al. Partial intracapsular tonsillectomy in the treatment of pediatric obstructive sleep apnea/hypopnea syndrome: a prospective study with 5-year follow-up[J]. Eur Arch Otorhinolaryngol, 2022, 279(6): 3089-3093. doi: 10.1007/s00405-021-07119-3
|
| [13] |
高淑蔚, 郭永丽, 许志飞. 阻塞性睡眠呼吸暂停综合征儿童腺样体扁桃体切除术后治疗效果及其预测因素的研究进展[J]. 中华耳鼻咽喉头颈外科杂志, 2020, 55(6): 630-634.
|
| [14] |
刘留. 鼻内镜下低温等离子行腺样体切除联合鼓室置管治疗儿童阻塞性睡眠呼吸暂停低通气综合征伴分泌性中耳炎的效果[J]. 山西医药杂志, 2020, 49(21): 2952-2955.
|
| [15] |
常媛, 邱志利, 蒋晓平, 等. 鼻内镜手术联合低温等离子射频消融术治疗鼻腔鼻窦内翻性乳头状瘤的疗效及对术后复发的影响[J]. 解放军医药杂志, 2021, 33(1): 31-34.
|
| [16] |
赵娜, 鲁海平. 低温等离子手术治疗儿童阻塞性睡眠呼吸暂停低通气综合征疗效分析[J]. 中国临床医生杂志, 2021, 49(1): 111-114.
|
| [17] |
龙松良, 赵斯君, 黄敏, 等. 鼻内窥镜下低温等离子射频消融术治疗小儿鼾症伴过敏性鼻炎的效果[J]. 中国医药导报, 2019, 16(12): 93-96.
|
| [18] |
付奕豪, 周跃飞, 杨双武, 等. 经鼻内镜脑脊液鼻漏修补探讨[J]. 空军军医大学学报, 2022, 43(5): 436-439.
|
| [19] |
姚庆根, 储俊才, 王慧. 经鼻内镜再手术治疗复发性鼻窦炎鼻息肉的疗效观察[J]. 实用临床医药杂志, 2018, 22(9): 98-100. doi: 10.7619/jcmp.201809027
|
| [20] |
刘彦洁, 郝伟华, 姜芳, 等. 硫辛酸用于阻塞性睡眠呼吸暂停低通气综合征抗炎治疗的临床疗效及对SOD、丙二醛水平影响[J]. 湖南师范大学学报: 医学版, 2020, 17(4): 28-30.
|
| [21] |
郑伟, 党珊, 张智勇, 等. 远端缺血预处理对对乙酰氨基酚诱导急性肝损伤小鼠氧化应激和炎症反应的保护作用[J]. 肝胆胰外科杂志, 2021, 33(12): 741-746.
|
| [22] |
刘伟玲, 刘伟旗, 周少雄. 甲状腺疾病患者血清超氧化物歧化酶、维生素E与甲状腺激素的相关性研究[J]. 检验医学与临床, 2019, 16(6): 749-751, 754.
|
| [23] |
徐云侠, 李萍, 储明子, 等. 压疮模型大鼠血清和组织中超氧化物歧化酶与一氧化氮的实验观察[J]. 中华全科医学, 2016, 14(12): 1998-2001.
|
| [24] |
孙国义, 吴宝俊, 詹红星. 鼻内窥镜下低温等离子射频消融术对小儿鼾症伴过敏性鼻炎通气功能的影响[J]. 贵州医药, 2019, 43(5): 758-759.
|
| 1. |
荣会蓉，周金成，夏思，杨凡. 急性胰腺炎患儿血清中ATG7的表达及疾病进展的相关性研究. 现代消化及介入诊疗. 2023(05): 564-567+572 .
|
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