Changes of serological indexes and prognosis of acute coronary syndrome patients after percutaneous coronary intervention

LI Xiaoyu; ZHANG Yongyong; QIN Juan; YANG Zhongxin

doi:10.7619/jcmp.20231532

Journal of Clinical Medicine in Practice > 2023 > 27(23): 60-62, 67. > DOI: 10.7619/jcmp.20231532

LI Xiaoyu, ZHANG Yongyong, QIN Juan, YANG Zhongxin. Changes of serological indexes and prognosis of acute coronary syndrome patients after percutaneous coronary intervention[J]. Journal of Clinical Medicine in Practice, 2023, 27(23): 60-62, 67. DOI: 10.7619/jcmp.20231532

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Changes of serological indexes and prognosis of acute coronary syndrome patients after percutaneous coronary intervention

1.
Department of Cardiovascular Medicine, the First Affiliated Hospital of Henan University, Kaifeng, Henan, 475000
2.
Department of Thoracic Surgery, the First Affiliated Hospital of Henan University, Kaifeng, Henan, 475000

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Received Date: May 11, 2023
Revised Date: September 27, 2023
Available Online: December 25, 2023

Graphical Abstract

Abstract

Abstract

Objective
To investigate the levels of N-terminal probrain natriuretic peptide (NT-proBNP), thrombolomodulin (TM), C-type lectin-like receptor 2 (CLEC-2), galectin-3 (Gal-3) and their relationships with prognosis in patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI).
Methods
A total of 80 patients with ACS were selected as study objects. The patients were followed up for 6 months by outpatient visit or telephone follow-up, and the occurrence of major adverse cardiovascular events (MACE) was recorded in the patients. According to the occurrence of MACE, patients were divided into MACE group (26 cases) and control group (54 cases). The changes of serological indexes were compared between the two groups.
Results
The expression levels of NT-proBNP, CLEC-2, TM and Gal-3 in serum of patients in the MACE group were significantly higher than those of control group (P < 0.05). Multivariate Logistic regression analysis showed that NT-proBNP, CLEC-2, TM, and Gal-3 were all influential factors for the occurrence of MACE after PCI in ACS patients (P < 0.05).
Conclusion
NT-proBNP, CLEC-2, TM and Gal-3 are influencing factors for MACE in patients with ACS after PCI, and have a good predictive role in evaluating the occurrence of MACE.

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References (17)

References

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