Research progress on risk factors of delayed encephalopathy caused by acute carbon monoxide poisoning

ZHANG Shimian; ZENG Xianrong

doi:10.7619/jcmp.20231898

Journal of Clinical Medicine in Practice > 2023 > 27(22): 138-142, 148. > DOI: 10.7619/jcmp.20231898

ZHANG Shimian, ZENG Xianrong. Research progress on risk factors of delayed encephalopathy caused by acute carbon monoxide poisoning[J]. Journal of Clinical Medicine in Practice, 2023, 27(22): 138-142, 148. DOI: 10.7619/jcmp.20231898

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Research progress on risk factors of delayed encephalopathy caused by acute carbon monoxide poisoning

ZHANG Shimian^{1, 2},
ZENG Xianrong^2, ,

1.
School of Medicine of University of Electronic Science and Technology of China, Chengdu, Sichuan, 610054
2.
Department of Internal Neurology, Sichuan Provincial People's Hospital, Chengdu, Sichuan, 610072

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Received Date: June 11, 2023
Revised Date: August 28, 2023
Available Online: December 05, 2023

Graphical Abstract

Abstract

Abstract

Acute carbon monoxide poisoning (ACOP) is a frequent asphyxiating gas poisoning event in winter in China, most of which develop into delayed encephalopathy of acute carbon monoxide poisoning (DEACMP) after 2 to 60 days of false recovery, which seriously endangers individuals, families and society. At present, the pathogenesis of DEACMP is not clear and cannot be completely prevented. This paper reviewed the risk factors associated with DEACMP in order to provide reference for the diagnosis and treatment of the disease.
- carbon monoxide poisoning,
- delayed encephalopathy,
- risk factors,
- clinical features,
- biological markers,
- ancillary examinations,
- treatment modality

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References (60)

References

[1]	MATTIUZZI C, LIPPI G. Worldwide epidemiology of carbon monoxide poisoning[J]. Hum Exp Toxicol, 2020, 39(4): 387-392. doi: 10.1177/0960327119891214
[2]	OUAHMANE Y, HATTIMY F E, SOULAYMANI A, et al. Hyperbaric oxygen therapy in carbon monoxide poisoning in Moroccan patients[J]. Acta Neurol Belg, 2023, 123(1): 139-143. doi: 10.1007/s13760-021-01688-0
[3]	HU H J, PAN X W, WAN Y, et al. Factors affecting the prognosis of patients with delayed encephalopathy after acute carbon monoxide poisoning[J]. Am J Emerg Med, 2011, 29(3): 261-264. doi: 10.1016/j.ajem.2009.09.030
[4]	ZHANG Y X, LU Q S, JIA J, et al. Multicenter retrospective analysis of the risk factors for delayed neurological sequelae after acute carbon monoxide poisoning[J]. Am J Emerg Med, 2021, 46: 165-169. doi: 10.1016/j.ajem.2020.06.090
[5]	MU C D, CHEN J J, GUO T Y, et al. Potential markers for predicting delayed encephalopathy in patients with acute carbon monoxide poisoning[J]. J Clin Neurosci, 2022, 95: 129-133. doi: 10.1016/j.jocn.2021.11.022
[6]	CARDIM D, CZOSNYKA M, CHANDRAPATHAM K, et al. Arterial and venous cerebral blood flow velocities and their correlation in healthy volunteers and traumatic brain injury patients[J]. J Neurosurg Anesthesiol, 2022, 34(1): e24-e33. doi: 10.1097/ANA.0000000000000704
[7]	LIU Z, MENG H, HUANG J T, et al. Acute carbon monoxide poisoning with low saturation of carboxyhaemoglobin: a forensic retrospective study in Shanghai, China[J]. Sci Rep, 2021, 11(1): 18554. doi: 10.1038/s41598-021-97436-8
[8]	SUZUKI Y. Risk factors for delayed encephalopathy following carbon monoxide poisoning: importance of the period of inability to walk in the acute stage[J]. PLoS One, 2021, 16(3): e0249395. doi: 10.1371/journal.pone.0249395
[9]	王运锋, 陈风兰, 郑惠之, 等. 急性一氧化碳中毒迟发性脑病的临床特征及危险因素[J]. 西部医学, 2020, 32(10): 1496-1499. doi: 10.3969/j.issn.1672-3511.2020.10.019
[10]	SUN R M, CAO W Y, JI Z G, et al. Predictive values of serum biochemical markers and apparent diffusion coefficient on delayed encephalopathy after acute carbon monoxide poisoning[J]. Turk Neurosurg, 2021, 31(6): 851-856.
[11]	SERT E T, KOKULU K, MUTLU H. Clinical predictors of delayed neurological sequelae in charcoal-burning carbon monoxide poisoning[J]. Am J Emerg Med, 2021, 48: 12-17. doi: 10.1016/j.ajem.2021.04.001
[12]	GAO Y, GU H, YANG J, et al. Prognosis of patients in prolonged coma after severe carbon monoxide poisoning[J]. Hum Exp Toxicol, 2021, 40(8): 1355-1361. doi: 10.1177/0960327121997992
[13]	王玲, 吐亚, 姚振滨, 等. 非职业性一氧化碳中毒患者迟发性脑病的相关因素[J]. 吉林医学, 2022, 43(5): 1230-1234. doi: 10.3969/j.issn.1004-0412.2022.05.024
[14]	RAMESH P, CHAUHAN A, GOYAL P, et al. H-FABP: a beacon of hope for prediabetic heart disease[J]. J Family Med Prim Care, 2020, 9(7): 3421-3428. doi: 10.4103/jfmpc.jfmpc_296_20
[15]	DAS S, ROY S, SHARMA V, et al. Association of ACE gene I/D polymorphism and ACE levels with hemorrhagic stroke: comparison with ischemic stroke[J]. Neurol Sci, 2015, 36(1): 137-142. doi: 10.1007/s10072-014-1880-8
[16]	KOYLU R, CANDER B, DUNDAR Z D, et al. The importance of H-FABP in determining the severity of carbon monoxide poisoning[J]. J Clin Med Res, 2011, 3(6): 296-302.
[17]	王广军, 石瑜, 高夫海, 等. 神经因子、炎症因子水平对急性一氧化碳中毒迟发性脑病的预测价值及其相关性研究[J]. 现代医学与健康研究电子杂志, 2022, 6(18): 116-119. https://www.cnki.com.cn/Article/CJFDTOTAL-XYJD202218036.htm
[18]	孔辉. 急性一氧化碳中毒患者血清CK、CRP水平与迟发性脑病的相关性探讨[J]. 航空航天医学杂志, 2020, 31(4): 454-455. doi: 10.3969/j.issn.2095-1434.2020.04.037
[19]	ZHANG L T, ZHAO J, HAO Q Q, et al. Serum NSE and S100B protein levels for evaluating the impaired consciousness in patients with acute carbon monoxide poisoning[J]. Medicine, 2021, 100(25): e26458. doi: 10.1097/MD.0000000000026458
[20]	MOON J M, CHUN B J, LEE S D, et al. Serum neuron-specific enolase levels at presentation and long-term neurological sequelae after acute charcoal burning-induced carbon monoxide poisoning[J]. Clin Toxicol, 2018, 56(8): 751-758. doi: 10.1080/15563650.2017.1415347
[21]	XIE J L, PANG C Y, YU H, et al. Leukocyte indicators and variations predict worse outcomes after intravenous thrombolysis in patients with acute ischemic stroke[J]. J Cereb Blood Flow Metab, 2023, 43(3): 393-403. doi: 10.1177/0271678X221142694
[22]	YALÇIN G, TUNCA H, SAYINBATUR B, et al. Predictive value of complete blood count, venous blood gas measurements, and glucose/potassium ratio for delayed neuropsychiatric syndrome in children with acute carbon monoxide poisoning due to coal-burning stove[J]. Turk Arch Pediatr, 2023, 58(3): 328-335. doi: 10.5152/TurkArchPediatr.2023.22282
[23]	冯程程, 朱瑞霞, 何志义. 脑梗死患者血清miR-181c、miR-21水平与颈动脉狭窄及其不良预后的相关性预测[J]. 西部医学, 2022, 34(6): 851-855. doi: 10.3969/j.issn.1672-3511.2022.06.015
[24]	王珊, 崔晓光, 周期, 等. miR-124在右美托咪定减轻缺血性卒中大鼠神经功能损伤中的作用研究[J]. 临床误诊误治, 2023, 36(3): 143-148. doi: 10.3969/j.issn.1002-3429.2023.03.031
[25]	景少巍, 朱浩轩, 杨晓燕, 等. 血清外泌体微小RNA-21与微小RNA-124水平变化在一氧化碳中毒并发迟发性脑病中的临床意义[J]. 感染、炎症、修复, 2022, 23(1): 13-18. https://www.cnki.com.cn/Article/CJFDTOTAL-GRYX202201003.htm
[26]	马辰, 韩莉娟. 血清sST2、Caspase-3、HSP70与ACMP患者病情和迟发性脑病的关系[J]. 检验医学与临床, 2023, 20(12): 1690-1694, 1699. doi: 10.3969/j.issn.1672-9455.2023.12.006
[27]	SHAREBIANI H, MOHARERI M, MIRHOSSEINI A, et al. The IL-33/sST2 axis in thromboangiitis obliterans[J]. J Inflamm Res, 2020, 13: 317-323. doi: 10.2147/JIR.S253980
[28]	CHEN Z, CAO T L, ZHONG X J, et al. Association between serum netrin-1 levels and early neurological deterioration after acute ischemic stroke[J]. Front Neurol, 2022, 13: 953557. doi: 10.3389/fneur.2022.953557
[29]	KOKULU K, MUTLU H, SERT E T. Serum netrin-1 levels at presentation and delayed neurological sequelae in unintentional carbon monoxide poisoning[J]. Clin Toxicol, 2020, 58(12): 1313-1319. doi: 10.1080/15563650.2020.1743302
[30]	LI W Q, ZHANG Y X, GU R J, et al. DNA pooling base genome-wide association study identifies variants at NRXN3 associated with delayed encephalopathy after acute carbon monoxide poisoning[J]. PLoS One, 2013, 8(11): e79159. doi: 10.1371/journal.pone.0079159
[31]	XU L L, LIU X J, ZHAO J, et al. Association between neuron-specific enolase gene polymorphism and delayed encephalopathy after acute carbon monoxide poisoning[J]. Behav Neurol, 2020, 2020: 8819210.
[32]	ZHANG F, ZENG J, ZHANG X L, et al. Investigation of the relationship between MBP gene polymorphisms and delayed encephalopathy after acute carbon monoxide poisoning[J]. Neurotoxicology, 2023, 94: 217-222. doi: 10.1016/j.neuro.2022.12.002
[33]	LIU X J, ZENG J, ZHANG X L, et al. The relationship between cadherin polymorphisms and the risk of delayed encephalopathy after acute carbon monoxide poisoning in the Chinese Han population[J]. Behav Neurol, 2022, 2022: 3155703.
[34]	谢燕. 磁共振弥散加权成像参数对急性一氧化碳中毒迟发性脑病的诊断及脑损伤评估作用[J]. 山西医药杂志, 2022, 51(13): 1465-1467. https://www.cnki.com.cn/Article/CJFDTOTAL-SXYY202213006.htm
[35]	KIM Y S, CHA Y S, KIM M S, et al. The usefulness of diffusion-weighted magnetic resonance imaging performed in the acute phase as an early predictor of delayed neuropsychiatric sequelae in acute carbon monoxide poisoning[J]. Hum Exp Toxicol, 2018, 37(6): 587-595. doi: 10.1177/0960327117722821
[36]	WANG T H, ZHANG Y L, GU Y Q, et al. Neurological sequelae in acute carbon monoxide poisoning: a prospective observational study with MRI data[J]. Acta Neurol Scand, 2022, 145(5): 590-598. doi: 10.1111/ane.13587
[37]	TSAI P H, CHOU M C, CHIANG S W, et al. Early white matter injuries in patients with acute carbon monoxide intoxication: a tract-specific diffusion kurtosis imaging study and STROBE compliant article[J]. Medicine, 2017, 96(5): e5982. doi: 10.1097/MD.0000000000005982
[38]	DU X Q, GU H, HAO F T, et al. Utility of brain CT for predicting delayed encephalopathy after acute carbon monoxide poisoning[J]. Exp Ther Med, 2019, 17(4): 2682-2688.
[39]	杜欢, 钱坤, 宋江峰, 等. 一氧化碳中毒迟发性脑病脑电图及磁共振成像影像学应用[J]. 实用医学影像杂志, 2022, 23(1): 68-71. https://www.cnki.com.cn/Article/CJFDTOTAL-SYXY202201022.htm
[40]	王春艳, 李俊. 102例一氧化碳中毒患者脑电图分析及对迟发性脑病的预测意义[J]. 中国实用医药, 2017, 12(25): 52-53. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSSA201725025.htm
[41]	PITTALIS A, CAVINATO M, ROMANO S, et al. Correlation between bispectral index and EEG[J]. Minerva Anestesiol, 2021, 87(9): 1056-1057.
[42]	WANG S B, LIU Y J, LIU H, et al. Clinical application of BIS combined with LCR in assessing brain function and prognosis of patients with severe carbon monoxide poisoning[J]. Clin Neurol Neurosurg, 2023, 224: 107556.
[43]	谢静, 徐丽霞, 吕爱红. 高压氧联合维生素C治疗急性一氧化碳中毒患者的临床分析[J]. 实用临床医药杂志, 2020, 24(14): 94-96. doi: 10.7619/jcmp.202014025
[44]	张杨, 李翠红, 杜晓芹, 等. 高压氧治疗介入时机对中重度急性一氧化碳中毒患者预后的影响[J]. 第三军医大学学报, 2020, 42(5): 523-527. https://www.cnki.com.cn/Article/CJFDTOTAL-DSDX202005015.htm
[45]	凌敬华, 高宗良, 沈志龙, 等. 不同高压氧疗程对CO中毒患者神经认知功能及并发症发生率的影响[J]. 立体定向和功能性神经外科杂志, 2020, 33(3): 155-160. https://www.cnki.com.cn/Article/CJFDTOTAL-NENG202003008.htm
[46]	王运锋, 胡蓉, 季一飞, 等. 首次强化高压氧治疗重度急性一氧化碳中毒[J]. 西部医学, 2020, 32(4): 524-526, 531. https://www.cnki.com.cn/Article/CJFDTOTAL-XIBU202004015.htm
[47]	HUANG F L, YANG L, TAN Z, et al. Prognostic factors of hyperbaric oxygen therapy for patients with delayed encephalopathy after acute carbon monoxide poisoning[J]. Heliyon, 2022, 8(12): e12351.
[48]	XIANG W P, XUE H, WANG B J, et al. Combined application of dexamethasone and hyperbaric oxygen therapy yields better efficacy for patients with delayed encephalopathy after acute carbon monoxide poisoning[J]. Drug Des Devel Ther, 2017, 11: 513-519.
[49]	徐丹, 宋大庆. 大剂量激素联合高压氧治疗DEACMP的临床效果[J]. 中国城乡企业卫生, 2021, 36(11): 133-135. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCXW202111054.htm
[50]	李伟民, 田小菲, 田栋安, 等. 雌激素对一氧化碳中毒小鼠脑白质脱髓鞘的抑制作用及机制研究[J]. 微循环学杂志, 2021, 31(4): 7-12. https://www.cnki.com.cn/Article/CJFDTOTAL-WXHX202104002.htm
[51]	项文平, 王宝军, 薛慧, 等. 白细胞介素-6和髓鞘碱性蛋白在急性一氧化碳中毒迟发性脑病中的作用[J]. 脑与神经疾病杂志, 2020, 28(11): 697-702. https://www.cnki.com.cn/Article/CJFDTOTAL-LYSJ202011010.htm
[52]	KIM S, CHOI S, KO Y, et al. Dexamethasone therapy prevents delayed neuropsychiatric sequelae after carbon monoxide poisoning: a prospective registry-based study[J]. Clin Toxicol, 2023, 61(2): 98-103.
[53]	TSAI H C, CHEN Y H. Dexamethasone downregulates the expressions of MMP-9 and oxidative stress in mice with eosinophilic meningitis caused by Angiostrongylus cantonensis infection[J]. Parasitology, 2021, 148(2): 187-197.
[54]	YOSHIMI N, FUTAMURA T, BERGEN S E, et al. Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis[J]. Mol Psychiatry, 2016, 21(11): 1504-1510.
[55]	DI S, MAXSON M M, FRANCO A, et al. Glucocorticoids regulate glutamate and GABA synapse-specific retrograde transmission via divergent nongenomic signaling pathways[J]. J Neurosci, 2009, 29(2): 393-401.
[56]	罗欣, 高怡, 杨金翰, 等. 外源性一氧化碳释放分子对体外培养PC12细胞的谷氨酸兴奋性神经毒性[J]. 职业卫生与应急救援, 2022, 40(2): 140-144. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYWS202202003.htm
[57]	秦静, 李自力, 张立平, 等. 急性CO中毒患者激素干预对血清TNF-α, IL-8水平的影响[J]. 第四军医大学学报, 2005(19): 1747. https://www.cnki.com.cn/Article/CJFDTOTAL-DSJY200519011.htm
[58]	平虎, 蒲燕, 汤进, 等. 心肌型脂肪酸结合蛋白、红细胞分布宽度、半胱氨酸天冬氨酸蛋白酶-3、基质金属蛋白酶-9、胱抑素C、肿瘤坏死因子-α联合检测对急性一氧化碳中毒患者预后的预测价值[J]. 陕西医学杂志, 2022, 51(11): 1432-1436. https://www.cnki.com.cn/Article/CJFDTOTAL-SXYZ202211027.htm
[59]	姚鹏. 一氧化碳中毒脑损伤早期体温控制对迟发型脑病和神经系统损伤的影响[J]. 浙江实用医学, 2022, 27(4): 329-331. https://www.cnki.com.cn/Article/CJFDTOTAL-ZJSA202204009.htm
[60]	ZHANG J J, BI W K, CHENG Y M, et al. Early predictors of brain injury in patients with acute carbon monoxide poisoning and the neuroprotection of mild hypothermia[J]. Am J Emerg Med, 2022, 61: 18-28.

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