Current status and prospects of tertiary lymphatic structures in organ transplant rejection reactions

After organ transplantation, graft rejection is one of the most common complications, which will cause adverse injuries to grafts regardless of etiology. Tertiary lymphoid structures (TLS) occur in non-lymphoid tissues under pathological conditions. Identification and characterization of mechanisms regulating graft rejection can not only promote understanding of the survival and prognosis of organ grafts, but also provide ideas for treating graft rejection reaction.