| Citation: |
WEI Guohui, SUN Yan, LIU Zhijie, LYU Hangyu, CHEN Yongxue, WANG Xinbo. Effect of erector spinae plane block on ultrasound-based hemodynamic parameters of arteries of four limbs and biochemical stress indicators in patients with thoracoscopic lobectomy[J]. Journal of Clinical Medicine in Practice, 2024, 28(14): 49-53. DOI: 10.7619/jcmp.20240574
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To investigate the effect of erector spinae plane block on ultrasound-based hemodynamic parameters of the arteries of the four limbs and biochemical stress indicators in patients with thoracoscopic lobectomy.
A total of 120 patients with thoracoscopic lobectomy were randomly divided into study group and control group, with 60 cases in each group.The study group received erector spinae plane block during surgery, while the control group received conventional anesthesia measures.Pulmonary function indicators[peak expiratory flow rate (PEFR), forced vital capacity (FVC), forced expiratory volume in the first second (FEV1)], ultrasound-based hemodynamic parameters of the arteries of the four limbs (maximum systolic velocity, minimum diastolic velocity, mean velocity, arterial pulsatility index, and arterial resistance index), stress indicators[cortisol (Cor), norepinephrine (NE), angiotensin Ⅱ(Ang Ⅱ), and adrenocorticotropic hormone (ACTH)], and analgesic effect were compared between the two groups at different time points[before anesthesia induction (T0), after extubation (T1), and after drainage tube removal (T2)].
FEV1, FVC and PEFR in both groups were significantly lower at T1 and T2 than at T0, and FEV1, FVC and PEFR in the study group were significantly higher than those in the control group at T1 and T2(P < 0.05).The maximum systolic velocity and arterial resistance index in both groups were significantly lower at T1 and T2 than at T0, while the minimum diastolic velocity, mean velocity and arterial pulsatility index were significantly higher at T1 and T2 than at T0(P < 0.05).The maximum systolic velocity and arterial resistance index in the study group were significantly higher than those in the control group at T1 and T2, but the minimum diastolic velocity, mean velocity and arterial pulsatility index were significantly lower than those in the control group (P < 0.05).Cor, ACTH, Ang Ⅱ and NE in both groups were significantly higher at T2 than at T0, and Cor, ACTH, Ang Ⅱ and NE in the study group were significantly lower than those in the control group at T2(P < 0.05).The Prince-Henry pain score, effective compression times, and actual compression times in the study group were significantly lower than those in the control group (P < 0.05).
Application of erector spinae plane block in thoracoscopic lobectomy causes smaller fluctuations in hemodynamic parameters of the arteries of four limbs and biochemical stress indicators, with a better anesthetic effect.
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