Effect of transurethral plasmakinetic resection of prostate in treating benign prostatic hyperplasia complicated with hypertension

WANG Mingbang; CHEN Changsha; LIU Rongzhen; XU Jianfeng

doi:10.7619/jcmp.20241211

Journal of Clinical Medicine in Practice > 2024 > 28(15): 90-94. > DOI: 10.7619/jcmp.20241211

WANG Mingbang, CHEN Changsha, LIU Rongzhen, XU Jianfeng. Effect of transurethral plasmakinetic resection of prostate in treating benign prostatic hyperplasia complicated with hypertension[J]. Journal of Clinical Medicine in Practice, 2024, 28(15): 90-94. DOI: 10.7619/jcmp.20241211

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Effect of transurethral plasmakinetic resection of prostate in treating benign prostatic hyperplasia complicated with hypertension

1.
Department of Urinary Surgery, Jinjiang Hospital of Fujian Province, Fujian Hospital of Shanghai Sixth People's Hospital, Quanzhou, Fujian, 362000
2.
Department of Medical Imaging, Jinjiang Hospital of Fujian Province, Fujian Hospital of Shanghai Sixth People's Hospital, Quanzhou, Fujian, 362000

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Received Date: March 21, 2024
Revised Date: May 14, 2024

Graphical Abstract

Abstract

Abstract

Objective
To compare the effects of transurethral plasmakinetic resection of prostate (TUPKRP) and drug therapy on blood pressure and change of blood pressure rhythm in patients with benign prostatic hyperplasia complicated with hypertension.
Methods
A total of 103 patients with benign prostatic hyperplasia in the hospital from June 2021 to June 2023 were retrospectively enrolled as study objects. According to different treatment protocols, they were divided into drug therapy group with 47 cases (treated with telmisartan combined with finasteride) and surgical treatment group with 56 cases (treated with telmisartan combined with TUPKRP). Blood pressure levels (24-hour mean diastolic blood pressure, 24-hour mean systolic blood pressure, daytime mean diastolic blood pressure, daytime mean systolic blood pressure, nighttime mean diastolic blood pressure, nighttime mean systolic blood pressure), change of blood pressure rhythm (dipper blood pressure), prostate symptoms, prostate volume, residual urine volume, and sexual function were compared between the two groups before treatment and at 3 and 6 months after treatment.
Results
The mean blood pressure at different time points in the surgical treatment group was significantly lower than that in the drug therapy group at 3 and 6 months after treatment (P < 0.05). The conversion rates of dipper blood pressure in the surgical treatment group at 3 and 6 months after treatment were 67.86% and 87.50%, which were significantly higher than 40.42% and 68.09% in the drug therapy group (P < 0.05). International Prostate Symptom Score (IPSS), residual urine volume, and prostate volume in the surgical treatment group were significantly lower than those in the drug therapy group at 3 and 6 months after treatment (P < 0.05). There was no significant difference in sexual function between the two groups before treatment and at 3 and 6 months after treatment (P>0.05).
Conclusion
Telmisartan combined with TUPKRP can reduce blood pressure levels, regulate change of blood pressure rhythm, improve prostate symptoms, reduce prostate volume, and decrease residual urine volume in patients with benign prostatic hyperplasia complicated with hypertension, with minimal impact on sexual function.
- benign prostatic hyperplasia,
- hypertension,
- transurethral plasmakinetic resection of prostate,
- blood pressure,
- blood pressure rhythm

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References

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Effect of transurethral plasmakinetic resection of prostate in treating benign prostatic hyperplasia complicated with hypertension

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