| Citation: |
GAO Shuhong, WANG Zhengfang, YAO Liwen, LIU Xingxiang, CUI Lin. Effect of bundled nursing on recurrent obstructive esophageal cancer treated by photodynamic therapy[J]. Journal of Clinical Medicine in Practice, 2025, 29(2): 129-132. DOI: 10.7619/jcmp.20242446
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To explore the application of bundled nursing care for recurrent obstructive esophageal cancer treated by photodynamic therapy.
Thirty patients with recurrent obstructive esophageal cancer were administered with photosensitizer hematoporphyrin derivative injection. After 24 hours, an optical fiber was introduced under endoscopic guidance, and 630 nm laser was used to irradiate the tumor locally. The degree of relief in dysphagia, improvement in performance status, changes in body mass index, and treatment-related adverse reactions were recorded. Bundled nursing strategies were implemented, including preoperative assessment, education, preparation, postoperative positioning, observation, prevention of complications, and light protection measures.
After treatment, the median diameter of the narrowest esophageal lesion was increased [(8.92±0.64) mm versus (4.77±0.60) mm], the Karnofsky Performance Status (KPS) score was improved [(77.69±5.99) versus (84.62±6.60)], BMI was increased [(17.17±1.66) kg/m2 versus (18.08±1.60) kg/m2], and the Stooler dysphagia grade was decreased compared with treatment before. The main treatment-related adverse reactions were retrosternal pain and fever.
Photodynamic therapy for recurrent obstructive esophageal cancer has a rapid onset of action and mild adverse reactions, and ensures the smooth implementation of PDT and patients'safety.
| [1] |
JIN M R, SHI L Y, WANG L, et al. Dihydroartemisinin enhances the anti-tumour effect of photodynamic therapy by targeting PKM2-mediated glycolysis in oesophageal cancer cell[J]. J Enzyme Inhib Med Chem, 2024, 39(1): 2296695. doi: 10.1080/14756366.2023.2296695
|
| [2] |
成乐楠, 葛利葱, 卢晓莉, 等. 5-氨基酮戊酸光动力疗法治疗子宫颈低级别鳞状上皮内病变合并高危型人乳头瘤病毒感染的疗效观察[J]. 实用临床医药杂志, 2021, 25(6): 20-24.
|
| [3] |
胡茹, 郭怀娟, 王颖, 等. C-PLAN指数作为免疫检查点抑制剂治疗晚期食管癌预后指标的临床研究[J]. 实用临床医药杂志, 2024, 28(1): 1-6, 12.
|
| [4] |
DING Y, LI W, LI B, et al. Comparison between photodynamic therapy and interventional esophageal stent implantation in dysphagia caused by advanced esophageal cancer[J]. Zhonghua Yi Xue Za Zhi, 2020, 100(5): 378-381.
|
| [5] |
WU H, MINAMIDE T, YANO T. Role of photodynamic therapy in the treatment of esophageal cancer[J]. Dig Endosc, 2019, 31(5): 508-516. doi: 10.1111/den.13353
|
| [6] |
中国抗癌协会肿瘤光动力治疗专业委员会. 呼吸道肿瘤光动力治疗临床应用中国专家共识[J]. 中华肺部疾病杂志: 电子版, 2020, 13(1): 6-12.
|
| [7] |
司琪, 吴锦姬. 集束化护理的概念分析[J]. 循证护理, 2024, 10(15): 2661-2665.
|
| [8] |
杨海燕, 刘汉, 陈红, 等. 连枷胸合并肺挫伤患者行有创通气的监护[J]. 实用临床医药杂志, 2008, 4(6): 60-61.
|
| [9] |
TANG R, CHEN G F, JIN K, et al. Efficacy of continuous gastric artery infusion chemotherapy in relieving digestive obstruction in advanced gastric cancer[J]. World J Gastrointest Oncol, 2023, 15(7): 1283-1294. doi: 10.4251/wjgo.v15.i7.1283
|
| [10] |
SCHWARTZ L H, SEYMOUR L, LITIōRE S, et al. RECIST 1.1-Standardisation and disease-specific adaptations: Perspectives from the RECIST Working Group[J]. Eur J Cancer, 2016, 62: 138-145. doi: 10.1016/j.ejca.2016.03.082
|
| [11] |
FREITES-MARTINEZ A, SANTANA N, ARIAS-SANTIAGO S, et al. Using the common terminology criteria for adverse events (CTCAE - version 5. 0) to evaluate the severity of adverse events of anticancer therapies[J]. Actas Dermosifiliogr, 2021, 112(1): 90-92.
|
| [12] |
FRIENDLANDER A H, ETTINGER R L. Karnofsky performance status scale[J]. Spec Care Dentist, 2009, 29(4): 147-148.
|
| [13] |
王莉娜, 李伟, 王颖. 综合护理干预与常规护理在光动力疗法治疗食管癌中的应用随机对照研究[J]. 现代消化及介入诊疗, 2017, 22(1): 142-144.
|
| [14] |
司桃, 范晓莉, 姜美娟, 等. 切削手术联合氨基酮戊酸光动力治疗1例Olmsted综合征患儿的护理[J]. 全科护理, 2023, 21(29): 4173-4176.
|
| [15] |
OZOG D M, RKEIN A M, FABI S G, et al. Photodynamic therapy: a clinical consensus guide[J]. Dermatol Surg, 2016, 42(7): 804-827.
|
| [16] |
徐丽. 综合护理干预在食管癌护理临床路径中的应用效果[J]. 医学美学美容, 2020, 29(1): 156-156.
|
| [17] |
YANO T, WANG K K. Photodynamic therapy for gastrointestinal cancer[J]. Photochem Photobiol, 2020, 96(3): 517-523.
|
| [18] |
顾广明, 崔林, 秦晓斌, 等. 姜堰市男性肺癌精神因素作用病例对照研究[J]. 中国肿瘤, 2003, 12(11): 628-629.
|
| [19] |
刘嘉, 骆峻, 曾庆琪. 恶性肿瘤患者心理因素与社会支持的研究进展[J]. 中国肿瘤外科杂志, 2017, 9(5): 331-333.
|
| [20] |
NANASHIMA A, NAKASHIMA K, KAWAKAMI H, et al. Nursing care management of photodynamic therapy in digestive tract carcinomas at a single cancer center[J]. Photodiagnosis Photodyn Ther, 2017, 17: 221-225.
|
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