Diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging combined with diffusion-weighted imaging for prostate cancer

ZHANG Yuanfei

doi:10.7619/jcmp.20242599

Journal of Clinical Medicine in Practice > 2024 > 28(24): 26-30. > DOI: 10.7619/jcmp.20242599

ZHANG Yuanfei. Diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging combined with diffusion-weighted imaging for prostate cancer[J]. Journal of Clinical Medicine in Practice, 2024, 28(24): 26-30. DOI: 10.7619/jcmp.20242599

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Diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging combined with diffusion-weighted imaging for prostate cancer

ZHANG Yuanfei

Department of Urological Surgery, Ma'anshan Shiqiye Hospital in Anhui Province, Ma'anshan, Anhui, 243000

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Received Date: June 18, 2024
Revised Date: September 10, 2024

Graphical Abstract

Abstract

Abstract

Objective
To analyze the diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) combined with diffusion-weighted imaging (DWI) in prostate cancer (PCa).
Methods
A total of 94 patients with prostate diseases were selected as study subjects, and divided into PCa group (n=41) and benign prostatic hyperplasia (BPH) group (n=53). The general information of the two groups was compared. The diagnostic efficacy of DCE-MRI and DWI examination parameters in PCa and their correlation with serum prostate-specific antigen (PSA) were analyzed.
Results
There were statistically significant differences in total prostate-specific antigen (tPSA), free prostate-specific antigen (fPSA)/tPSA, prostate volume (V), prostate-specific antigen density (PSAD), plasma volume fraction (V_p), reflux rate constant (K_ep), volume transfer constant (K^trans), extracellular extravascular volume fraction (V_e) and apparent diffusion coefficient (ADC) between the two groups (P < 0.05). The area under the curve for the combined prediction of PCa using DCE-MRI and DWI examination parameters was 0.924, which was greater than that for individual predictors or the combination of DCE-MRI examination parameters. K^trans, K_ep and V_e were positively correlated with tPSA and negatively correlated with fPSA/tPSA, while V_p and ADC were negatively correlated with tPSA and positively correlated with fPSA/tPSA (P < 0.05).
Conclusion
The combination of DCE-MRI and DWI has high diagnostic value for predicting PCa, and K^trans, K_ep, V_e, V_p and ADC have certain correlations with tPSA and fPSA/tPSA.

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References (20)

References

[1]	李宏基, 赵晓龙, 胡伟, 等. 前列腺癌早期筛查风险预测模型的建立与验证研究[J]. 中国全科医学, 2024, 27(20): 2483-2490. doi: 10.12114/j.issn.1007-9572.2023.0862
[2]	项天河. 血清前列腺特异性抗原、前列腺特异性抗原密度和可溶性上皮钙黏蛋白水平检测对前列腺癌的诊断价值[J]. 中国当代医药, 2022, 29(17): 173-176. doi: 10.3969/j.issn.1674-4721.2022.17.046
[3]	陈建春, 易凤连, 邱永友, 等. 磁共振DCE-TIC曲线联合DWI-ADC值对非囊性卵巢肿瘤良恶性的鉴别诊断价值[J]. 影像研究与医学应用, 2023, 7(8): 31-33. doi: 10.3969/j.issn.2096-3807.2023.08.010
[4]	谢艳琴. 多b值弥散加权成像(DWI)联合磁共振动态增强扫描(DCE-MRI)在前列腺癌术前分期中的诊断价值[J]. 甘肃医药, 2023, 42(5): 420-422.
[5]	陈爽, 陈子健, 钟建锋, 等. 动态对比增强磁共振联合PSA诊断前列腺癌价值探讨[J]. 中国CT和MRI杂志, 2022, 20(1): 142-145.
[6]	张丽平, 吴亚珊, 阮立文, 等. 前列腺癌Gleason分级系统新进展[J]. 新疆医学, 2023, 53(4): 464-467.
[7]	马东岳, 杨九天, 赵子维, 等. 中医药治疗良性前列腺增生症的作用机制研究[J]. 世界中医药, 2023, 18(3): 435-439.
[8]	王硕, 辛宇强, 彭飞, 等. 动态增强磁共振成像影像学参数联合CD55基因表达在乳腺癌预后评估中的效能研究[J]. 中国医学装备, 2022, 19(11): 74-78. doi: 10.3969/J.ISSN.1672-8270.2022.11.015
[9]	刘俊杰, 张岚. DCE-MRI与DWI定量分析在前列腺癌诊断和分级中的应用[J]. 河南医学研究, 2021, 30(17): 3113-3117. doi: 10.3969/j.issn.1004-437X.2021.17.011
[10]	MA X Z, LV K, SHENG J L, et al. Application evaluation of DCE-MRI combined with quantitative analysis of DWI for the diagnosis of prostate cancer[J]. Oncol Lett, 2019, 17(3): 3077-3084.
[11]	崔胜宏, 马秀梅, 闫红梅, 等. DCE-MRI联合血清sE-cadherin、AGR2检测诊断前列腺癌的临床价值[J]. 现代肿瘤医学, 2021, 29(14): 2490-2496. doi: 10.3969/j.issn.1672-4992.2021.14.021
[12]	何瑶, 彭梦晗, 李丹, 等. MRI动态增强扫描联合DWI定量参数对前列腺癌的诊断价值分析[J]. 基层医学论坛, 2021, 25(13): 1873-1875.
[13]	崔亚东, 李春媚, 韩思圆, 等. 合成MRI定量参数对前列腺癌的诊断价值[J]. 中华放射学杂志, 2021, 55(9): 975-980. doi: 10.3760/cma.j.cn112149-20200721-00935
[14]	陈妹, 陈玲, 曹明杰. 游离前列腺特异性抗原联合癌胚抗原对前列腺癌的早期诊断价值[J]. 中国现代医学杂志, 2020, 30(20): 82-86. doi: 10.3969/j.issn.1005-8982.2020.20.017
[15]	张超, 李晓琴, 壮健, 等. 经直肠剪切波弹性成像联合肿瘤标记物对早期前列腺癌的诊断价值研究[J]. 中国超声医学杂志, 2020, 36(12): 1126-1129. doi: 10.3969/j.issn.1002-0101.2020.12.018
[16]	张苏波, 徐永军, 孙毅, 等. PI-RADS v2. 1联合PSA相关指标预测PSA灰区前列腺癌的价值研究[J]. CT理论与应用研究, 2021, 30(5): 567-574.
[17]	高靖, 詹永豪. 血清TPSA、FPSA水平及其比值对前列腺癌的诊断价值及其与根治术后生化复发的相关性分析[J]. 实用癌症杂志, 2024, 39(5): 757-760. doi: 10.3969/j.issn.1001-5930.2024.05.016
[18]	胡起立, 宋黎涛, 黄松. 3. 0T动态增强MRI联合fPSA/tPSA检测对前列腺癌的诊断效能[J]. 影像科学与光化学, 2020, 38(5): 871-875.
[19]	程丽, 汪秀玲, 孙小伶. 多参数磁共振成像技术预测前列腺癌患者手术预后的价值分析[J]. 中国CT和MRI杂志, 2024, 22(5): 130-133.
[20]	盛伟华, 黄松, 李烨, 等. DCE-MRI定量参数联合ADC值诊断前列腺癌的价值及与血清PSA的相关性分析[J]. 川北医学院学报, 2020, 35(3): 461-464. doi: 10.3969/j.issn.1005-3697.2020.03.027

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