Effect of multidisciplinary collaboration model in patients with systemic lupus erythematosus during pregnancy
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摘要:目的
观察多学科协作模式在妊娠期系统性红斑狼疮(SLE)患者中的应用效果。
方法采用随机数字表法将60例妊娠期SLE患者分为常规护理组和强化护理组，每组30例。常规护理组采用常规护理，强化护理组采用多学科协作模式强化护理，观察并比较2组患者心理状态[焦虑自评量表(SAS)、抑郁自评量表(SDS)评分]、分娩成功率和SLE复发情况。
结果护理后, 2组患者SAS评分、SDS评分均低于护理前，且强化护理组SAS评分、SDS评分低于常规护理组，差异有统计学意义(P < 0.05)。2组均未出现SLE复发患者，但各有1例患者流产，其余患者均正常分娩。
结论将多学科协作模式应用于妊娠期SLE患者中，能够显著减轻患者抑郁、焦虑状态。
Abstract:ObjectiveTo observe the application effect of multidisciplinary collaboration model in patients with systemic lupus erythematosus(SLE) during pregnancy.
MethodsSixty patients with SLE in pregnancy were divided into routine nursing group(n=30) and intensive nursing group(n=30) by random number table method. Patients in the routine nursing group were treated with routine nursing, and patients in the intensive nursing group were treated with intensive nursing based on multidisciplinary collaboration model. The psychological status[Self-rating Anxiety Scale (SAS), self-rating Depression Scale (SDS) scores], delivery success rate and recurrence condition of SLE were observed and compared between the two groups.
ResultsAfter nursing, SAS score and SDS score of two groups were lower than before nursing, and SAS score and SDS score of intensive nursing group were lower than the routine nursing group, the differences were statistically significant (P < 0.05). There were no SLE recurrence patients in the two groups, but one patient in each group had abortion, and the other patients delivered normally.
ConclusionMultidisciplinary collaboration model can significantly reduce depression and anxiety in SLE patients during pregnancy.
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Keywords:
- systemic lupus erythematosus /
- pregnancy /
- multidisciplinary collaboration model /
- Wechat /
- anxiety /
- depression
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表 1 2组患者焦虑、抑郁水平比较[M(P25, P75)]
分 组别 n SAS评分 SDS评分 护理前 护理后 护理前 护理后 常规护理组 30 65.6(62.2, 67.5) 63.1(57.5, 65.3)* 62.5(57.2, 65.0) 60.0(54.7, 61.6)* 强化护理组 30 62.5(60.0, 67.5) 55.0(51.3, 58.1)*# 62.5(60.0, 67.5) 50.0(44.7, 52.5)*# SAS: 焦虑评分量表; SDS: 抑郁自评量表。与护理前比较, *P < 0.05; 与常规护理组比较, #P < 0.05。 
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表 2 2组患者实验室指标比较[M(P25, P75)]
指标 常规护理组(n=30) 强化护理组(n=30) 护理前 护理后 护理前 护理后 抗双链DNA抗体/(IU/mL) 29.5(23.5, 35.0) 23.0(15.0, 37.8) 24.5(16.0, 37.0) 21.5(13.0, 41.0) 补体C3/(g/L) 1.3(0.8, 2.0) 1.2(0.8, 1.8) 1.6(1.0, 2.5) 1.5(0.8, 3.1) 24 h尿蛋白/mg 52.0(23.8, 95.0) 43.0(24.8, 74.3) 36.0(24.5, 69.8) 29.0(20.8, 53.3)
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