Evaluation of carotid geometry of the internal carotid artery atheromatous plaque by head and neck CT angiography imaging

HUANG Zhifei; ZHU Youling; DONG Bin; ZHAI Dengyue; XU Qiaoqiao

doi:10.7619/jcmp.20230458

Journal of Clinical Medicine in Practice > 2023 > 27(13): 65-70. > DOI: 10.7619/jcmp.20230458

HUANG Zhifei, ZHU Youling, DONG Bin, ZHAI Dengyue, XU Qiaoqiao. Evaluation of carotid geometry of the internal carotid artery atheromatous plaque by head and neck CT angiography imaging[J]. Journal of Clinical Medicine in Practice, 2023, 27(13): 65-70. DOI: 10.7619/jcmp.20230458

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Evaluation of carotid geometry of the internal carotid artery atheromatous plaque by head and neck CT angiography imaging

Department of Neurology, the Third Affiliated Hospital of Anhui Medical University, Hefei First People's Hospital of Anhui Province, Anhui, Hefei, 230061

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Received Date: February 17, 2023
Revised Date: May 03, 2023
Available Online: July 18, 2023

Graphical Abstract

Abstract

Abstract

Objective
To investigate the relationship between different carotid geometry and the formation of atherosclerotic plaque in the initial part of internal carotid artery (ICA) in patients with ischemic stroke based on CT angiography (CTA) of head and neck.
Methods
Data of patients hospitalized for ischemic stroke and who completed head and neck CTA were retrospectively collected. Ninety-two patients with atherosclerotic plaques at the beginning of unilateral ICA were included in the plaque group, and 30 patients with bilateral normal ICA with similar demographic variables were selected as the control group. At the same time, unilateral ICA initiation atherosclerotic plaque were divided into plaque side and non-plaque side. The differences of carotid artery geometry between the two groups and in the plaque and non-plaque sides were compared.
Results
The geometric parameters of carotid artery, such as internal carotid artery angle, carotid artery dilation and ICA/common carotid artery (CCA) diameter ratio in the plaque group showed significant difference compared with those in the control group (P < 0.05). Compared with the non-plaque side, the internal carotid artery angle on the plaque side was significantly larger, carotid artery dilation was significantly higher, and ICA/CCA diameter ratio was significantly lower (P < 0.05). Multivariate Logistic regression analysis results showed that larger internal carotid artery angle and carotid artery dilatation and lower ICA/CCA diameter ratio were associated with atherosclerotic plaque formation at ICA initiation.
Conclusion
The geometric features of carotid artery are different among different individuals. In patients with mild ICA atherosclerotic lesions, larger internal carotid artery angle, carotid artery dilation and smaller ICA/CCA diameter ratio are independent risk factors for atherosclerotic plaque formation at the initiation of ICA.
- carotid artery,
- atherosclerosis,
- geometry,
- wall shear stress,
- hemodynamics,
- CT angiography

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References (22)

References

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Evaluation of carotid geometry of the internal carotid artery atheromatous plaque by head and neck CT angiography imaging