XU Weiliang, NIE Furong, CAO Qiwen, LUO Ensi. Diagnostic value of serum thyroglobulin antibody, thyroid microsomal antibody and thyroid peroxidase antibody in autoimmune thyroid disease[J]. Journal of Clinical Medicine in Practice, 2014, (5): 10-12. DOI: 10.7619/jcmp.201405004
Citation: XU Weiliang, NIE Furong, CAO Qiwen, LUO Ensi. Diagnostic value of serum thyroglobulin antibody, thyroid microsomal antibody and thyroid peroxidase antibody in autoimmune thyroid disease[J]. Journal of Clinical Medicine in Practice, 2014, (5): 10-12. DOI: 10.7619/jcmp.201405004

Diagnostic value of serum thyroglobulin antibody, thyroid microsomal antibody and thyroid peroxidase antibody in autoimmune thyroid disease

More Information
  • Published Date: July 14, 2014
  • Objective To explore the diagnostic value of serum thyroglobulin antibody (TGAb),thyroid microsomal antibody (TMAb)and thyroid peroxidase antibody (TPOAb)in au-toimmune thyroid disease (AITD).Methods 100 patients with thyroid dysfunction were divided into hyperthyroidism group and hypothyroidism group according to the levels of serum triiodothy-ronine (T3),thyroxine (T4)and thyroid stimulating hormone (TSH),50 cases in each group.An-other 50 patients with normal thyroid function were collected and designed as control group.5 mL venous blood was collected,and the serum was separated.The levels of TGAb,TMAb,TPOAb, T3,T4 and TSH were detected by radioimmunoassay in each group,positive rates of TGAb,TMAb and TPOAb were observed,and the serum levels of positive TGAb,TMAb and TPOAb were com-pared among all the groups.Results The positive rate of serum TPOAb was significantly higher than those of TGAb and TMAb in hyperthyroidism group and hypothyroidism group.The positive rates of serum TGAb,TMAb and TPOAb in hyperthyroidism and hypothyroidism groups were sig-nificantly higher than the control group,and those in hypothyroidism group were higher than hy-perthyroidism group.The levels of serum TGAb,TMAb and TPOAb in hyperthyroidism group and hypothyroidism group were significantly higher than the control group,and those in hypothyroidism group were obviously higher than hyperthyroidism group.Conclusion TPOAb shows an important significance in diagnosing AITD,which provides an important evidence for AITD diagnosis, treatment and prognosis.
  • Related Articles

    [1]SHAO Zhongxin, LI Shiying. Effect of propofol regulating macrophage polarization on airway inflammatory response and Toll-like receptor 4-NOD-like receptor protein 3 pathway in mice with bronchial asthma[J]. Journal of Clinical Medicine in Practice, 2025, 29(6): 13-19. DOI: 10.7619/jcmp.20245587
    [2]ZHANG Pan, WEI Yuanyuan, WANG Hao, WANG Xianwei, LI Yanqing, SUN Xue. Effect of Callicarpa nudiflora on wound healing and PI3K/AKT/mTOR pathway by regulating M2 macrophage polarization in rats with diabetic foot ulcer[J]. Journal of Clinical Medicine in Practice, 2025, 29(4): 44-49, 54. DOI: 10.7619/jcmp.20243269
    [3]CHEN Ziqing, WANG Ke, ZOU Wenjun. Research progress on macrophage-like cells at vitreoretinal interface[J]. Journal of Clinical Medicine in Practice, 2024, 28(11): 139-143. DOI: 10.7619/jcmp.20241091
    [4]WANG Lifei, LUO Longlong, ZHENG Ying, LU Lixia, LI Bin, WANG Junke, LI Chuyi, YU Xiaohui, ZHANG Jiucong. Research progress on macrophage migration inhibitory factor in hepatocellular carcinoma[J]. Journal of Clinical Medicine in Practice, 2023, 27(14): 126-130. DOI: 10.7619/jcmp.20231220
    [5]XIAO Yinggang, GAO Ju. Research progress in regulation of microglial polarization by RhoA/ROCK signaling pathway[J]. Journal of Clinical Medicine in Practice, 2022, 26(20): 136-141, 148. DOI: 10.7619/jcmp.20221217
    [6]DU Borong, XU Yanfeng, WEI Zhiqiang. Vitamin C alleviates macular degeneration in rats by regulating function of macrophages[J]. Journal of Clinical Medicine in Practice, 2022, 26(17): 130-134. DOI: 10.7619/jcmp.20220296
    [7]LU Hangcheng, WEI Weiwei, CHEN Jiming, SHI Ruxia. Research progress of targeted therapy for cervical cancer by tumor-associated macrophages[J]. Journal of Clinical Medicine in Practice, 2021, 25(7): 123-127, 132. DOI: 10.7619/jcmp.20201759
    [8]WU Dandan, DING Shizhen, LU Guotao, XIAO Weiming, GONG Weijuan. Effect of ANGPTL 4 on M2 macrophages differentiation[J]. Journal of Clinical Medicine in Practice, 2018, (9): 1-5. DOI: 10.7619/jcmp.201809001
    [9]WU Qiyong, QI Chunjian, CHEN Chen, WANG Yong. Effect of tumor-associated macrophages on promotion of proliferation and metastasis of non-small cell lung cancer[J]. Journal of Clinical Medicine in Practice, 2016, (9): 101-104. DOI: 10.7619/jcmp.201609029
    [10]HU Jian, YIN Shibao, YE Aqi, QIAN Yun, LI Demin. Protective effect of erythropoietin on renal injury following cardiopulmonary bypass in rats[J]. Journal of Clinical Medicine in Practice, 2013, (9): 9-12. DOI: 10.7619/jcmp.201309003
  • Cited by

    Periodical cited type(16)

    1. 张艳,陈小龙,刘静,张秀珍. 桃红四物汤合防己黄芪汤结合空气压力波治疗仪预防术后下肢深静脉血栓的效果观察. 四川中医. 2024(04): 127-130 .
    2. 赖玲治,陈婷婷,白亚铃,李焕根. 气压治疗仪联合红外线照射预防重症患者下肢深静脉血栓. 中国医学物理学杂志. 2024(11): 1415-1420 .
    3. 袁晓莉,张丽杰. 依诺肝素钠联合空气波压力治疗仪对高危产妇剖宫产术后下肢DVT的防治效果及对微循环、PAF、CD62P、CD63的影响. 临床医学研究与实践. 2023(25): 78-81 .
    4. 张霞,王妙维,王任杰,李果,王傲,尹雨涵,魏全. 人体成分分析仪联合空气循环压力在防治乳腺癌相关淋巴水肿的临床应用. 湖南师范大学学报(医学版). 2023(04): 71-74 .
    5. 曾桂金. 空气治疗仪对剖宫产后高龄产妇下肢静脉血栓形成率的影响分析. 基层医学论坛. 2022(06): 130-132 .
    6. 严丽金,曾兆芬,罗淑芳,张东丽. 护理研究持续性阶段护理干预服务减低剖宫产产妇疼痛及提高产后母乳喂养的价值评估. 医学食疗与健康. 2022(09): 130-132 .
    7. 郭杏英. 空气波压力治疗仪联合加压弹力袜对剖宫产术后下肢静脉血栓的预防. 实用医技杂志. 2022(06): 664-666 .
    8. 史军艳,蒋晓娟. 空气波压力治疗仪联合多元化护理预防全子宫切除术后患者下肢深静脉血栓形成的临床效果. 医疗装备. 2022(20): 172-174 .
    9. 郭敬敬,曹曰针,王柱. 小剂量阿司匹林预防剖宫产后下肢静脉血栓的效果. 中国继续医学教育. 2021(12): 160-164 .
    10. 韦宝珍. 预防神经外科患者下肢静脉血栓形成的护理综述. 外科研究与新技术. 2021(01): 74-77 .
    11. 孟媛媛. 空气波压力治疗仪联合穴位按摩对肝胆手术后下肢深静脉血栓及褥疮的预防作用研究. 临床医学. 2021(05): 85-87 .
    12. 陈雪芳,吴敏瑜,苏文英. 气压治疗仪联合常规术后护理对剖宫产后凝血指标的调节作用. 名医. 2021(01): 127-128 .
    13. 艾艳霞,樊菊莲,苏丽. 阿司匹林及气压仪预防高龄剖宫产产妇术后下肢深静脉血栓形成. 血栓与止血学. 2021(06): 1021-1022 .
    14. 潘玉琴,陶婷,吴晔. 空气压力波治疗仪联合体感诱发电位监测预防脊柱骨折术后下肢深静脉血栓形成的应用效果. 中国医学物理学杂志. 2021(12): 1554-1559 .
    15. 曾瑜嫚. 剖宫产产妇术后采用空气波压力治疗仪降低双下肢深静脉血栓形成的重要性. 医学食疗与健康. 2021(11): 208-209 .
    16. 郭蕊. 空气波压力治疗仪配合早期护理干预对剖宫产术后下肢深静脉血栓的预防效果. 医疗装备. 2020(14): 160-161 .

    Other cited types(0)

Catalog

    Article views (382) PDF downloads (1) Cited by(16)

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return