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JIA Xiaolin, LI Na. Clinical efficiency of laparoscopic ovarian perforation combined with clomiphene citrate and human chorionic gonadotropin in treating infertility induced by polycystic ovary syndrome[J]. Journal of Clinical Medicine in Practice, 2019, 23(7): 102-105. DOI: 10.7619/jcmp.201907027
Citation: JIA Xiaolin, LI Na. Clinical efficiency of laparoscopic ovarian perforation combined with clomiphene citrate and human chorionic gonadotropin in treating infertility induced by polycystic ovary syndrome[J]. Journal of Clinical Medicine in Practice, 2019, 23(7): 102-105. DOI: 10.7619/jcmp.201907027
shu

Clinical efficiency of laparoscopic ovarian perforation combined with clomiphene citrate and human chorionic gonadotropin in treating infertility induced by polycystic ovary syndrome

  • 1.

    Department of Gynecology and Obstetrics, Fugu County Hospital of Traditional Chinese Medicine, Fugu, Shaanxi, 719499

  • 2.

    Department of Obstetrics, Affiliated Hospital of Yan′an University, Yan′an, Shaanxi, 716000

More Information
  • Received Date: December 15, 2018
  • Accepted Date: January 12, 2019
  • Available Online: September 09, 2020
  • Published Date: April 14, 2019
    Graphical Abstract
    • Abstract
  •   Objective  To explore the clinical efficiency of laparoscopic ovarian perforation combined with clomiphene citrate (CC) and human chorionic gonadotropin (HCG) in treating infertility induced by polycystic ovary syndrome (PCOS).
      Methods  Totally 68 patients with infertility induced by PCOS were randomly divided into two groups, with 34 cases in each group. The control group was treated with laparoscopic ovarian perforation and HCG, while the observation group was treated with laparoscopic ovarian perforation combined with CC and HCG. Therapeutic effect and pregnancy condition were compared between the two groups.
      Results  After treatment, the levels of luteinizing hormone, estradiol and testosterone in the observation group were significantly better than those in the control group (P < 0.05). In the observation group, the ovulation rate and one-year pregnancy rate were 91.18% and 58.82% respectively, which were significantly higher than 58.82% and 32.35% in the control group (P < 0.05). There were no adverse reactions in the control group, and the incidence rate of adverse reactions in the observation group was 5.58%. There was no significant difference between the two groups (P>0.05).
      Conclusion  Laparoscopic ovarian perforation combined with CC and HCG is effective in the treatment of infertility induced by PCOS, which can improve sex hormone level and increase ovulation rate and pregnancy rate.
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    • References (18)
  • [1]
    蔡秀丽, 姚金艳, 张义娇. 达英-35联合克罗米芬治疗多囊卵巢综合征所致不孕症的疗效分析[J]. 实用临床医药杂志, 2016, 20(15): 60-62. doi: 10.7619/jcmp.201615017
    [2]
    魏代敏, 潘烨, 石玉华. 多囊卵巢综合征辅助生殖治疗策略的优化[J]. 中华妇产科杂志, 2018, 53(1): 58-61. doi: 10.3760/cma.j.issn.0529-567x.2018.01.014
    [3]
    蒋琼, 张梅. 腹腔镜下卵巢打孔术治疗难治性多囊卵巢综合征临床观察[J]. 海南医学, 2016, 27(3): 475-477. doi: 10.3969/j.issn.1003-6350.2016.03.048
    [4]
    张亚琴, 蒋维, 韩炜. 微创手术联合药物治疗多囊卵巢综合征伴不孕对卵巢功能及生育能力的影响[J]. 中国性科学, 2017, 26(7): 126-129. doi: 10.3969/j.issn.1672-1993.2017.07.043
    [5]
    吴海, 何佳, 鄢利梅, 等. 腹腔镜卵巢打孔术联合中药治疗难治性多囊卵巢综合征不孕症疗效观察[J]. 现代中西医结合杂志, 2016, 25(8): 855-857. doi: 10.3969/j.issn.1008-8849.2016.08.019
    [6]
    燕海亚. 多囊卵巢综合征不孕症应用腹腔镜下卵巢打孔术的临床评价[J]. 中国医药导刊, 2016, 18(8): 79-81. https://www.cnki.com.cn/Article/CJFDTOTAL-DKYY201608019.htm
    [7]
    Li T C, 赵玉婷(译). 多囊卵巢综合征及卵巢打孔术[J]. 国际生殖健康/计划生育杂志, 2017, 36(3): 189-194.
    [8]
    姚钰虹, 王志新. 卵巢打孔术治疗枸橼酸氯米芬抵抗型多囊卵巢综合征不孕患者临床效果的荟萃分析[J]. 中国妇产科临床杂志, 2016, 11(5): 446-447. https://www.cnki.com.cn/Article/CJFDTOTAL-FKLC201605023.htm
    [9]
    谢幸, 苟文丽. 妇产科学[M]. 北京: 人民卫生出版社, 2013: 45-48.
    [10]
    赵晓苗, 李琳, 陈晓莉, 等. 伴有高雄激素血症的多囊卵巢综合征患者患有Ⅱ型糖尿病和肥胖的风险升高[J]. 生殖与避孕, 2017, 37(12): 969-974.
    [11]
    魏勉, 邱峰龙, 薛惠英. PCOS高雄激素血症患者降调节后行冻融胚胎移植的临床结局观察[J]. 生殖医学杂志, 2017, 26(7): 670-674. doi: 10.3969/j.issn.1004-3845.2017.07.010
    [12]
    郑思远, 张莹, 龙涛, 等. 不同胰岛素抵抗及肥胖水平对多囊卵巢综合征患者高雄激素血症特征的影响[J]. 广东医学, 2017, 38(3): 406-409. doi: 10.3969/j.issn.1001-9448.2017.03.022
    [13]
    吴慧芬. 腹腔镜卵巢打孔术联合补肾活血促排中药治疗难治性多囊卵巢综合征不孕症疗效观察[J]. 现代中西医结合杂志, 2017, 26(20): 2251-2253. doi: 10.3969/j.issn.1008-8849.2017.20.030
    [14]
    陈兰, 谈勇, 陈淑萍. 克罗米芬与定坤丹对PCOS不孕症临床促排卵和临床妊娠疗效的研究[J]. 中国中药杂志, 2017, 42(20): 4035-4039. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGZY201720028.htm
    [15]
    薛燕, 郭晓莉, 李春芳, 等. 腹腔镜微创手术对卵巢良性肿瘤患者机体创伤及卵巢功能的影响[J]. 河北医学, 2017, 23(2): 215-218. doi: 10.3969/j.issn.1006-6233.2017.02.012
    [16]
    徐姬妹. 腹腔镜下卵巢打孔术联合克罗米芬对难治性多囊卵巢综合征不孕患者的治疗效果评价[J]. 中国妇幼保健, 2016, 12(18): 3799-3801. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB201618056.htm
    [17]
    纪冬莉. 二甲双胍联合克罗米芬治疗PCOS合并不孕患者的疗效及对LH、T等激素水平的影响分析[J]. 实用妇科内分泌杂志: 电子版, 2016, 3(16): 64-65. https://www.cnki.com.cn/Article/CJFDTOTAL-FKDZ201616038.htm
    [18]
    玛依拉·买买提, 祖力皮亚·依明. 克罗米芬联合人绒毛膜促性腺激素对多囊卵巢综合征不孕患者促排卵的临床效果观察[J]. 实用临床医药杂志, 2017, 21(17): 72-75. https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL201717022.htm
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