Effect of remifentanil versus dezocine analgesia in middle pregnancy abortion

ZHANG Jin; HE Kun; LI Bo; ZHAO Haifeng; SHAO Xian; CHEN Liang

doi:10.7619/jcmp.201913011

Journal of Clinical Medicine in Practice > 2019 > 23(13): 39-41. > DOI: 10.7619/jcmp.201913011

ZHANG Jin, HE Kun, LI Bo, ZHAO Haifeng, SHAO Xian, CHEN Liang. Effect of remifentanil versus dezocine analgesia in middle pregnancy abortion[J]. Journal of Clinical Medicine in Practice, 2019, 23(13): 39-41. DOI: 10.7619/jcmp.201913011

Citation:

PDF (481 KB)

Effect of remifentanil versus dezocine analgesia in middle pregnancy abortion

Department of Anesthesiology, Fourth Hospital of Shijiazhuang, Shijiazhuang, Hebei, 050000

More Information

Received Date: April 21, 2019
Accepted Date: May 27, 2019
Available Online: February 23, 2021
Published Date: July 14, 2019

Graphical Abstract

Abstract

Abstract

Objective To compare the effect of remifentanil and dezocine analgesia in middle pregnancy abortion.
Methods A total of 80 middle pregnant induced labor cases were randomly divided into group R and group D, with 40 cases in each group. Group R was given intravenous infusion of remifentanil for analgesia at a dosage of 0.05~0.15 μg/(kg·min) by micro pump, and the dosage was adjusted to reach and maintain the level of analgesia. Group D was given 25 mg dezocine diluted to 50 mL normal saline, with abackground dose of 10 mL/h. A single intravenous analgesia dose of 5 mL/h was given to theses patients for intravenous self-controlled analgesia. Visual Analogue Scale (VAS) Scores, Ramsay sedation score, adjust times of analgesia, time to first pain after induction and occurrence of complications such as respiratory depression, bradycardia, nausea and vomiting were recorded.
Results At 30 min after analgesia, the VAS score in the R group was significantly higher than that in group D[(7.5±1.2) vs. (2.3±1.1), P < 0.05]; the Ramsay score in the group R was significantly higher than that in the group D [(2.5±0.2) vs. (2.3±0.3), P < 0.05); the times of analgesic adjustment in group R was significantly more, the time to first pain was significantly shorter, and the incidences of bradycardia and respiratory depression were significantly higher than that of group D (P < 0.05).
Conclusion Compared with remifentanil, dezocine intravenous analgesia for middle pregnancy abortion women with easy operation and cooperation can avoid the occurrence of hyperalgesia, and reduce incidence of adverse reactions.
- middle pregnancy abortion,
- remifentanil,
- dezocine,
- analgesic,
- opioid,
- hyperalgesia

FullText(HTML)

References (13)

References

[1]	Orbach-Zinger S, Paul-Keslin L, Nichinson E, et al. Tramadol-metoclopramide or remifentanil for patient-controlled analgesia during second trimester abortion: a double-blinded, randomized controlled trial[J]. J Clin Anesth, 2012, 24(1): 28-32. doi: 10.1016/j.jclinane.2011.05.003
[2]	Song J W, Lee Y W, Yoon K B, et al. Magnesium sulfate prevents remifentanil-induced postoperative hyperalgesia in patients undergoing thyroidectomy[J]. Anesth Analg, 2011, 113(2): 390-397. doi: 10.1213/ANE.0b013e31821d72bc
[3]	Lee C, Kim Y D, Kim J N. Antihyperalgesic effects of dexmedetomidine on high-dose remifentanil-induced hyperalgesia[J]. Korean J Anesthesiol, 2013, 64(4): 301-307. doi: 10.4097/kjae.2013.64.4.301
[4]	Wang C Y, Li L Z, Shen B X, et al. A multicenter randomized double-blind prospective study of the postoperative patient controlled intravenous analgesia effects of dezocine in elderly patients[J]. Int J Clin Exp Med, 2014, 7(3): 530-539. http://pubmedcentralcanada.ca/pmcc/articles/PMC3992390/
[5]	Song Y K, Lee C, Seo D H, et al. Interaction between postoperative shivering and hyperalgesia caused by high-dose remifentanil[J]. Korean J Anesthesiol, 2014, 66(1): 44-51. doi: 10.4097/kjae.2014.66.1.44
[6]	Kim S H, Stoicea N, Soghomonyan S, et al. Intraoperative use of remifentanil and opioid induced hyperalgesia/acute opioid tolerance: systematic review[J]. Front Pharmacol, 2014, 5: 108-108. http://pubmedcentralcanada.ca/pmcc/articles/PMC4021143/?lang=fr
[7]	Wang Z P, Edwards J G, Riley N, et al. Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity[J]. Cell, 2008, 135(3): 535-548. doi: 10.1016/j.cell.2008.09.057
[8]	刘颖群, 李萱, 程畅河, 等. 地佐辛联合罗哌卡因在中期妊娠引产镇痛中的应用研究[J]. 中国基层医药, 2014, 21(18): 2824-2825. doi: 10.3760/cma.j.issn.1008-6706.2014.18.044
[9]	徐维娟, 马军, 徐桂萍. 地佐辛不同给药时机对子宫肌瘤患者术后镇痛效果及淋巴免疫系统的影响[J]. 中国基层医药, 2013(20): 3119-3121. doi: 10.3760/cma.j.issn.1008-6706.2013.20.033
[10]	高丽娜, 衣丽丽, 丁浩, 等. 瑞芬太尼预注射在中期妊娠引产中的效果研究[J]. 中国处方药, 2015, 13(2): 119-120. doi: 10.3969/j.issn.1671-945X.2015.02.095
[11]	杨华平. 中期妊娠引产镇痛过程中地佐辛联合罗哌卡因的应用探讨[J]. 中外医疗, 2017, 36(1): 106-108. https://www.cnki.com.cn/Article/CJFDTOTAL-HZZZ201701039.htm
[12]	孙冰, 张丕兴, 田瑞云, 等. 瑞芬太尼PCIA与罗哌卡因PCEA在中期妊娠引产术中的应用[J]. 临床麻醉学杂志, 2011, 27(2): 191-192. https://www.cnki.com.cn/Article/CJFDTOTAL-LCMZ201102039.htm
[13]	王玥, 康凯, 车向明, 等. 硬膜外阻滞在中期妊娠引产镇痛时机选择的临床观察[J]. 北京医学, 2014, 36(11): 930-932. doi: 10.3969/j.issn.0253-9713.2014.11.018

[1]	WANG Guoli, YU Xuemei, ZHANG Ying. Application of non-cervical dilation hysteroscopic technique versus HEOS hysteroscopic technique in intrauterine adhesion separation[J]. Journal of Clinical Medicine in Practice, 2024, 28(20): 98-102. DOI: 10.7619/jcmp.20242177
[2]	TAO Jinyan, LI Changzheng, YANG Hongyan, LI Liya, ZHANG Dan. Correlation of disinfection quality of digestive endoscopes with residual tissue glue in forceps channels[J]. Journal of Clinical Medicine in Practice, 2024, 28(12): 18-20, 25. DOI: 10.7619/jcmp.20233673
[3]	ZHANG Jiali, YI Hongying, HAO Ling, LI Shangwen, CHEN Changxu. Effect of self-prescribed Paizhuo Qinggong Herbal Formula Granule combined with Misoprostol Tablets on uterine recovery in patients with residual intrauterine tissue after childbirth[J]. Journal of Clinical Medicine in Practice, 2024, 28(4): 55-60. DOI: 10.7619/jcmp.20233376
[4]	GU Zhuanrong. Effect of Xinshenghua Granule and Fresh Yimucao Capsule on improvement of acute hemorrhage after medical abortion[J]. Journal of Clinical Medicine in Practice, 2018, (7): 114-116. DOI: 10.7619/jcmp.201807032
[5]	YAO Fei, ZHANG Wenjing, XU Shaojun, ZHU Aibing, SHEN Mingkun. Effectiveness and safety of three different doses of oxycodone hydrochloride injection in treatment of postoperative uterus contraction pain after painless artificial abortion surgery[J]. Journal of Clinical Medicine in Practice, 2017, (21): 55-58. DOI: 10.7619/jcmp.201721016
[6]	QIN Wei, LIU Hong, XING Chunzi. Effect of iodophor uterine cavity wipe in prevention of postoperative incision infection in nursing intervention of cesarean section in high risk pregnant women[J]. Journal of Clinical Medicine in Practice, 2017, (20): 103-105. DOI: 10.7619/jcmp.201720033
[8]	MA Chun, TIAN Li. Influence of uterine perfusion with hCG in ovulatory period on endometrial pinopodes and clinical pregnancy rate in patients with RSA[J]. Journal of Clinical Medicine in Practice, 2016, (21): 69-71,75. DOI: 10.7619/jcmp.201621021
[9]	CHEN Jing, LI Mujun, HUANG Qianyi, CAI Junying, WAN Jiangfan. Expression of certain cytokines by Th17 cells in peripheral blood and decidual tissues of patients with unexplained recurrent spontaneous abortion[J]. Journal of Clinical Medicine in Practice, 2015, (9): 91-93. DOI: 10.7619/jcmp.201509026
[10]	LU Jian, ZHANG Enhu, WU Lin, YUE Ming, YAN Jianhua, ZHAI Xiaoyi. Study on the effects of Huaxiangongxue capsules on the uterine bleeding volume of rats with drugs-elicited incomplete abortion[J]. Journal of Clinical Medicine in Practice, 2013, (5): 21-23. DOI: 10.7619/jcmp.201305005

Cited By

Cited by

Periodical cited type(1)

孙佩佩，马丽丽，丁露碟，张浙恩. 应激性高血糖比值与伴2型糖尿病的急性心肌梗死患者急诊PCI术后预后的关系. 心电与循环. 2024(06): 594-597 .

Other cited types(0)

Get Citation

PDF

XML

Article views (277) PDF downloads (5) Cited by(1)

Turn off MathJax

Article Contents

Abstract

References

Effect of remifentanil versus dezocine analgesia in middle pregnancy abortion

Abstract

References

Related Articles

Cited by

Periodical cited type(1)

Other cited types(0)

Catalog

Effect of remifentanil versus dezocine analgesia in middle pregnancy abortion

Abstract

References

Related Articles

Cited by

Periodical cited type(1)

Other cited types(0)

Catalog

Export File

Citation

Format

Content