Objective To compare the effect of remifentanil and dezocine analgesia in middle pregnancy abortion.
Methods A total of 80 middle pregnant induced labor cases were randomly divided into group R and group D, with 40 cases in each group. Group R was given intravenous infusion of remifentanil for analgesia at a dosage of 0.05~0.15 μg/(kg·min) by micro pump, and the dosage was adjusted to reach and maintain the level of analgesia. Group D was given 25 mg dezocine diluted to 50 mL normal saline, with abackground dose of 10 mL/h. A single intravenous analgesia dose of 5 mL/h was given to theses patients for intravenous self-controlled analgesia. Visual Analogue Scale (VAS) Scores, Ramsay sedation score, adjust times of analgesia, time to first pain after induction and occurrence of complications such as respiratory depression, bradycardia, nausea and vomiting were recorded.
Results At 30 min after analgesia, the VAS score in the R group was significantly higher than that in group D(7.5±1.2) vs. (2.3±1.1), P < 0.05; the Ramsay score in the group R was significantly higher than that in the group D (2.5±0.2) vs. (2.3±0.3), P < 0.05); the times of analgesic adjustment in group R was significantly more, the time to first pain was significantly shorter, and the incidences of bradycardia and respiratory depression were significantly higher than that of group D (P < 0.05).
Conclusion Compared with remifentanil, dezocine intravenous analgesia for middle pregnancy abortion women with easy operation and cooperation can avoid the occurrence of hyperalgesia, and reduce incidence of adverse reactions.
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