Advance Search
HOU Xiaoxia, SUN Ting. Effect of endometrial thickness and transplantation time on the incidence of ectopic pregnancy in frozen thawed embryo transplantation[J]. Journal of Clinical Medicine in Practice, 2019, 23(21): 14-17. DOI: 10.7619/jcmp.201921004
Citation: HOU Xiaoxia, SUN Ting. Effect of endometrial thickness and transplantation time on the incidence of ectopic pregnancy in frozen thawed embryo transplantation[J]. Journal of Clinical Medicine in Practice, 2019, 23(21): 14-17. DOI: 10.7619/jcmp.201921004
shu

Effect of endometrial thickness and transplantation time on the incidence of ectopic pregnancy in frozen thawed embryo transplantation

  • 1.

    Department of Medical ultrasound, Northwest Women and Children′s Hospital, Xi′an, Shaanxi, 710003

  • 2.

    Department of Reproductive Center, Northwest Women and Children′s Hospital, Xi′an, Shaanxi, 710003

More Information
  • Received Date: August 09, 2019
  • Available Online: February 28, 2021
  • Published Date: November 14, 2019
    Graphical Abstract
    • Abstract
  •   Objective  To investigate the effect of the endometrial thickness and embryo transplantation (ET) time on the incidence of ectopic pregnancy in frozen thawed embryo transplantation.
      Methods  A prospective study of 11 681 frozen-thawed embryo transplantation cycles in the Reproductive Center of Northwest Women and Children′s Hospital was conducted to analyze the pregnancy outcomes, including 6 901 cycles of clinical pregnancy and 75 of ectopic pregnancy. According to the embryo transplantation time, the FET cycles were divided into D3 embryo transplantation group (5 912 cycles in embryo period) and D5 blastula transplantation group (5 949 cycles in blastula period). And were further subdivided into ≤9 mm group, >9~12 mm group and >12 mm group according to endometrial thickness. The incidence of ectopic pregnancy of varied groups were compared.
      Results  There were 45 cases with ectopic pregnancy in the D3 embryo transplantation group, and 30 cases in D5 blastocyst transplantation group, and its incidence of ectopic pregnancy showed a significant difference(P < 0.05). Compared with ≤9 mm group, the incidence of ectopic pregnancy in >9~12 mm group and >12 mm group were significantly lower.
      Conclusion  D5 blastula transplantation group has significantly lower risk of ectopic pregnancy than D3 embryo transplantation group, endometrial thickness can be independent factor of ectopic pregnancy.
    • FullText(HTML)
    • References (21)
  • [1]
    Creanga A A, Syverson C, Seed K, et al. Pregnancy-related mortality in the United States, 2011-2013[J]. Obstet Gynecol, 2017, 130(2): 366-373. doi: 10.1097/AOG.0000000000002114
    [2]
    Jurkovic D, Wllkinson H. Diagnosis and management of ectopic pregnancy[J]. BMJ, 2011, 342: d3397-d3405. doi: 10.1136/bmj.d3397
    [3]
    Refaat B, Dalton E, Ledger W L. Ectopic pregnancy secondary to in vitro fertilisation-embryo transfer: pathogenic mechanisms and management strategies[J]. Reprod Biol Endocrinol, 2015, 13: 30-37. doi: 10.1186/s12958-015-0025-0
    [4]
    Li C, Meng C X, Zhao W H, et al. Risk factors for ectopic pregnancy in women with planned pregnancy: a case-control study[J]. Eur J Obstet Gynecol Reprod Biol, 2014, 181: 176-182. doi: 10.1016/j.ejogrb.2014.07.049
    [5]
    Patil M. Ectopic pregnancy after infertility treatment[J]. J Hum Reprod Sci, 2012, 5(2): 154-161. doi: 10.4103/0974-1208.101011
    [6]
    Malak M, Tawfeeq T, Holzer H, et al. Risk factors for ectopic pregnancy after in vitro fertilization treatment[J]. J Obstet Gynaecol Can, 2011, 33(6): 617-619. doi: 10.1016/S1701-2163(16)34910-6
    [7]
    Bu Z Q, Xiong Y J, Wang K Y, et al. Risk factors for ectopic pregnancy in assisted reproductive technology: a 6-year, single-center study[J]. Fertil Steril, 2016, 106(1): 90-94. doi: 10.1016/j.fertnstert.2016.02.035
    [8]
    Chang H J, Suh C S. Ectopic pregnancy after assisted reproductive technology: what are the risk factors[J]. Curr Opin Obstet Gynecol, 2010, 22(3): 202-207. doi: 10.1097/GCO.0b013e32833848fd
    [9]
    Schoolcraft W B, Surrey E S, Gardner D K. Embryo transfer: techniques and variables affecting success[J]. Fertil Steril, 2001, 76(5): 863-870. doi: 10.1016/S0015-0282(01)02731-5
    [10]
    Ishihara O, Kuwahara A, Saitoh H. Frozen-thawed blastocyst transfer reduces ectopic pregnancy risk: an analysis of single embryo transfer cycles in Japan[J]. Fertil Steril, 2011, 95(6): 1966-1969. doi: 10.1016/j.fertnstert.2011.02.015
    [11]
    Smith L P, Oskowitz S P, Dodge L E, et al. Risk of ectopic pregnancy following day-5 embryo transfer compared with day-3 transfer[J]. Reprod Biomed Online, 2013, 27(4): 407-413. doi: 10.1016/j.rbmo.2013.06.015
    [12]
    Milki A A, Jun S H. Ectopic pregnancy rates with day 3 versus day 5 embryo transfer: a retrospective analysis[J]. BMC Pregnancy Childbirth, 2003, 3(1): 7-13. doi: 10.1186/1471-2393-3-7
    [13]
    Keegan D A, Morelli S S, Noyes N, et al. Lowectopic pregnancy rates after in vitro fertilization: do practice habits matter[J]. Fertil Steril, 2007, 88: 734-736. doi: 10.1016/j.fertnstert.2006.11.169
    [14]
    Rosman E R, Keegan D A, Krey L, et al. Ectopic pregnancy rates after in vitro fertilization: a look at the donor egg population[J]. Fertil Steril, 2009, 92: 1791-1793. doi: 10.1016/j.fertnstert.2009.05.041
    [15]
    Glujovsky D, Farquhar C, Quinteiro Retamar A M, et al. Cleavage stage versus blastocyst stage embryo transfer in assisted reproductive technology[J]. Cochrane Database Syst Rev, 2016(6): CD002118. doi: 10.1002/14651858.CD002118.pub3/pdf
    [16]
    Fanchin R, Ayoubi J M, Righini C, et al. Uterine contractility decreases at the time of blastocyst transfers[J]. Hum Reprod, 2001, 16(6): 1115-1119. doi: 10.1093/humrep/16.6.1115
    [17]
    王菁, 刘嘉茵, 崔毓桂. 异位妊娠发生机制研究进展及辅助生殖技术相关高危因素分析[J]. 国际生殖健康/计划生育杂志, 2013, 32(3): 203-206. https://www.cnki.com.cn/Article/CJFDTOTAL-GWJS201303017.htm
    [18]
    Ellaithy M, Abdelaziz A, Hassan M F. Outcome prediction in pregnancies of unknown location using endometrial thickness measurement: is this of real clinical value[J]. Eur J Obstet Gynecol Reprod Biol, 2013, 168(1): 68-74. doi: 10.1016/j.ejogrb.2012.12.026
    [19]
    Moschos E, Twickler D M. Endometrial thickness predicts intrauterinepregnancy in patients with pregnancy of unknown location[J]. Ultrasound Obstet Gynecol, 2008, 32: 929-934. doi: 10.1002/uog.6248
    [20]
    Rombauts L, Motteram C, Berkowitz E, et al. Risk of placenta praeviais linked to endometrial thickness in a retrospective cohort study of 4537singleton assisted reproduction technology births[J]. Hum Reprod, 2014, 29: 2787-2793. doi: 10.1093/humrep/deu240
    [21]
    Rombauts L, McMaster R, Motteram C, et al. Risk of ectopic pregnancy is linked to endometrial thickness in a retrospective cohort study of 8120 assisted reproduction technology cycles[J]. Hum Reprod, 2015, 30(12): 2846-2852. http://europepmc.org/abstract/MED/26428211
    • Related Articles

  • Related Articles

    [1]GUO Sijin, YAN Changjiao, WANG Yang, CAO Xiaohua, WANG Ting. Establishment and application of artificial intelligence voice follow-up system for differentiated thyroid cancer[J]. Journal of Clinical Medicine in Practice, 2024, 28(16): 1-4, 9. DOI: 10.7619/jcmp.20241127
    [2]YANG Yichen, ZOU Cao. Radiofrequency catheter ablation versus cryoballoon ablation for atrial fibrillation in long-term follow up results[J]. Journal of Clinical Medicine in Practice, 2022, 26(12): 10-13. DOI: 10.7619/jcmp.20220369
    [3]LI Yanhua, PU Shijun, SUI Mingxing, DUAN Yazhe, LU Xiaoying. Effect of full-time follow-up on quality of life in recipients with transplantation of donated kidney[J]. Journal of Clinical Medicine in Practice, 2022, 26(5): 58-61. DOI: 10.7619/jcmp.20213474
    [4]XUAN Dongping, QIAO Jin, ZHAO Yan, CHEN Xia. Influence of medication education combined with information follow-up on therapeutic effect in patients with type 2 diabetes mellitus in clinic[J]. Journal of Clinical Medicine in Practice, 2021, 25(16): 81-84. DOI: 10.7619/jcmp.20212369
    [5]HUANG Zhonghua. Effects evaluation of continuous follow-up in dry weight control of patients with long-term hemodialysis[J]. Journal of Clinical Medicine in Practice, 2016, (10): 35-38. DOI: 10.7619/jcmp.201610012
    [6]HOU Aihong. Effect of prenatal health follow-up on the delivery skills and delivery mode of primiparas[J]. Journal of Clinical Medicine in Practice, 2016, (8): 121-123. DOI: 10.7619/jcmp.201608037
    [7]WANG Xiaojuan, LIU Xiaomei, HAN Yufeng, LI Chen, WEI Yong, ZHANG Lili. The effect of WeChat platform in the follow-up intervention for premature infants[J]. Journal of Clinical Medicine in Practice, 2016, (4): 130-132. DOI: 10.7619/jcmp.201604040
    [8]ZHANG Fang, ZHANG Yaning, ZHAO Hua. Effect of WeChat follow up outside the hospital on self-careability of rectal cancer patients with rectostomy[J]. Journal of Clinical Medicine in Practice, 2016, (4): 107-110. DOI: 10.7619/jcmp.201604033
    [9]XU Jun, WANG Fang. Influence of nursing intervention during follow-up on symptoms and quality of life in non-hospitalized children with asthma[J]. Journal of Clinical Medicine in Practice, 2015, (12): 101-103. DOI: 10.7619/jcmp.201512032
    [10]ZHANG Huifang, LIU Meng. Telephone follow-up and health guidance for discharged puerperas with caesarean section[J]. Journal of Clinical Medicine in Practice, 2013, (10): 98-100. DOI: 10.7619/jcmp.201310036

  • Cited by

    Periodical cited type(45)

    1. 张辅满，林桦，缪卡莉，张哲，林靖，钟永鸣. 加置橡皮引流对促进肉芽肿性乳腺炎微创旋切术后康复的观察. 甘肃医药. 2024(02): 134-136 .
    2. 吴昊，王婷婷，宁伟，石亚楠，海艺贝. 超声下真空辅助微创旋切用于乳腺良性肿瘤的效果. 黑龙江医药科学. 2024(05): 146-148+152 .
    3. 钱敏，陈静，俞超，楼晨，吕锦恒. 乳腺循经温通技术治疗乳腺增生的疗效分析. 中国处方药. 2024(11): 165-167 .
    4. 周利人. 超声辅助麦默通乳腺微创旋切术对乳腺良性肿瘤患者手术相关指标及炎症因子的影响. 中国医学创新. 2023(07): 42-46 .
    5. 周瑶，肖尾丰，彭青群. 超声定位下微创旋切术治疗乳腺良性肿瘤的临床疗效及预后分析. 江西医药. 2023(03): 345-346+373 .
    6. 张忠玲，熊辉. 乳腺良性叶状肿瘤真空辅助旋切与开放手术对术后局部复发的影响. 医学信息. 2023(12): 133-135+139 .
    7. 常莹，郭卫宾，王江芬. 超声引导下乳腺微创旋切术联合循证护理对乳腺癌患者的影响. 现代医学与健康研究电子杂志. 2023(20): 109-112 .
    8. 杜京丽，黄嘉杰，洪亮，郑茂煌，傅志荣. 超声引导下微波消融与微创旋切术治疗乳腺良性肿瘤的效果及安全性. 中外医学研究. 2023(34): 119-122 .
    9. 郭冀鲁，李远，李芳，韩臻，刘学智，牛俊波. 超声辅助乳腺微创旋切术治疗乳腺良性肿瘤的效果及对应激反应的影响. 中国医学创新. 2023(35): 1-5 .
    10. 杜璐迪，刘翔，王莉娟，戴力. 乳管镜联合B超引导下微创旋切术治疗乳腺导管内良性肿瘤的疗效和安全性. 中国妇幼保健. 2022(07): 1341-1343 .
    11. 陈立丰. 乳腺良性肿瘤行微创旋切术与传统开刀术治疗的临床效果对比. 基层医学论坛. 2022(19): 139-141 .
    12. 吴琼. 乳腺外科微创手术患者手术室的护理配合及预后分析. 基层医学论坛. 2022(21): 16-18+40 .
    13. 候玉龙. 超声引导下麦默通微创旋切术应用于乳腺良性肿瘤的疗效分析及其疼痛、并发症情况观察. 吉林医学. 2022(07): 1948-1951 .
    14. 袁军华，曹娟，任超，王隽. 超声引导下微创旋切术治疗乳腺多发性肿块的效果及其对术后疼痛与应激反应的影响. 中外医学研究. 2022(18): 153-156 .
    15. 刘国庆. 超声引导下乳腺微创旋切术对乳腺肿块患者的疗效影响分析. 中国医疗器械信息. 2022(13): 106-108 .
    16. 张健瑀，盛燕红，王苗锋. 超声引导微创旋切术治疗乳腺纤维瘤的疗效研究. 浙江创伤外科. 2022(05): 907-908 .
    17. 王明佳，李晓旭，宋德霸，张晓剑. Mammotome微创旋切术治疗乳腺良性肿瘤的疗效分析. 上海医药. 2022(23): 33-36 .
    18. 胡晨波. 超声引导下微创旋切术对乳腺良性肿块患者围手术期指标及并发症的影响. 中国医学创新. 2022(35): 65-68 .
    19. 干江，王俊，李欢欢，陈燕燕. 乳癖祛瘀汤对乳腺结节旋切术后患者的影响. 光明中医. 2022(21): 3856-3858 .
    20. 宋磊. 乳腺微创旋切术在乳房良性肿瘤诊疗中的应用效果. 中国医疗器械信息. 2022(23): 144-146 .
    21. 洪云峰，谢毅坚，江文波. 超声引导下真空辅助旋切术治疗乳腺良性肿瘤的效果. 中外医学研究. 2022(35): 110-114 .
    22. 袁月欢，唐诗，李玉娟，杨波. 超声引导下微创旋切治疗乳腺良性肿瘤临床效果. 中国城乡企业卫生. 2021(01): 138-140 .
    23. 王珂. 全面护理干预策略在乳腺良性肿瘤患者围手术期中的应用. 黑龙江医药. 2021(01): 236-238 .
    24. 刘金平，李祥平，姚振宏. 乳腺良性肿瘤行超声引导下微创旋切术治疗的手术和美观效果观察. 基层医学论坛. 2021(05): 637-639 .
    25. 钱桂荣，孙菲，孙海波. 乳腺良性肿瘤患者超声引导下微创旋切术治疗的有效性及对患者并发症发生的影响. 影像研究与医学应用. 2021(08): 165-166 .
    26. 付飞国，王忆丽，雷秋模，李梦辉. 超声引导小切口微创旋切术应用于浆细胞性乳腺炎的效果研究. 基层医学论坛. 2021(22): 3119-3121 .
    27. 余汉辉，徐伟宏，梅锋，邱凌. 超声引导下麦默通乳腺微创旋切术与传统手术治疗乳腺良性肿瘤的效果对比. 中国实用医药. 2021(21): 79-81 .
    28. 黄小涛，顾泽苗. 乳腺旋切微创术治疗多发性乳腺纤维瘤患者的疗效及美容效果分析. 实用中西医结合临床. 2021(15): 75-76 .
    29. 王恩远. 超声引导真空辅助旋切术治疗乳腺良性占位病变的近期效果. 河南外科学杂志. 2021(05): 79-81 .
    30. 金俊超，郑依童，刘伟迪. 微创旋切术治疗乳腺良性肿瘤的临床疗效、安全性及对患者抑郁、焦虑情绪的影响. 国际精神病学杂志. 2021(05): 865-868 .
    31. 徐斌，卫利民，刘永萱，梁仁杰. 安珂真空辅助微创旋切术治疗乳腺良性肿瘤的疗效. 国际医药卫生导报. 2021(20): 3216-3219 .
    32. 何鹏，李永飞，吴意赟，任晓梅，卞卫和，姚昶. 超声引导下真空辅助旋切术与开放切除术治疗合并钙化灶乳腺肿块的效果比较. 实用临床医药杂志. 2021(22): 13-16 . 本站查看
    33. 张立光. 放射状切口与乳晕缘小切口切除术治疗乳腺良性肿瘤的对比. 系统医学. 2021(20): 120-124 .
    34. 韦杰峰. 超声引导下麦默通乳腺微创旋切术对乳腺良性肿瘤患者术后疗效影响观察. 影像研究与医学应用. 2021(23): 207-208+211 .
    35. 林庆军，杜丽，林燕晖，林燕纯，陈业晞. 乳腺表浅良性肿物应用水平式乳腺旋切切除效果分析. 中国现代医生. 2021(35): 58-61 .
    36. 姚晓波. 安珂真空辅助微创旋切术和传统开放式手术治疗200例乳腺肿瘤的效果比较. 四川解剖学杂志. 2020(01): 79-80 .
    37. 胡亚男，张英霞. 应用超声技术评估ATEC系统旋切乳腺良性肿块的研究. 影像研究与医学应用. 2020(04): 92-93 .
    38. 陈露文，叶永强. B超定位下的微创旋切术治疗乳腺良性肿块的临床疗效观察. 中国医学创新. 2020(25): 132-135 .
    39. 袁月欢，唐诗，李玉娟，杨波，陈媛媛，吴玲，温珮琦，邓杰华. 真空辅助旋切术在乳腺良性肿物患者中的价值及对复发率的影响. 中外医学研究. 2020(24): 25-27 .
    40. 付修林，杨荣. 真空辅助旋切术与传统乳腺肿物切除术在乳腺良性肿瘤治疗中的效果比较. 中国全科医学. 2020(S1): 163-165 .
    41. 张学东. 超声下微创旋切术治疗乳腺良性肿瘤的疗效观察. 实用中西医结合临床. 2020(12): 44-45+59 .
    42. 戴军，杨旭辉，吴晓，周志林，梅勇. 微创旋切术用于老年乳腺良性肿块患者对手术指标、应激反应和免疫功能的影响. 现代生物医学进展. 2020(21): 4051-4054 .
    43. 黄大翠，杨向贵，夏林玉. 安珂微创旋切系统在乳腺良性肿块切除中的应用及预后影响分析. 中国美容医学. 2020(12): 72-75 .
    44. 温冰馨，王斌. 超声引导下乳腺良性病灶微创旋切术的临床效果. 中国当代医药. 2020(32): 73-75 .
    45. 郑育民，李成宜. 乳腺微创旋切治疗非哺乳期乳腺炎的临床观察. 实用中西医结合临床. 2020(17): 131-133 .

    Other cited types(0)

Catalog

    Get Citation
    PDF
    XML
    Article views (231) PDF downloads (3) Cited by(45)
    Turn off MathJax
    Article Contents
    Abstract
    References
    Related Articles

    © 2020 《实用临床医药杂志》编辑部

    Address: 江苏省扬州市江阳中路136号，扬州大学江阳路北校区14号楼201室China Pos: 225009Tel: 0514-87978917、87978989、87978807

    苏公网安备 32100302010246号

    Supported by: Beijing Renhe Information Technology Co., Ltd.   Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return