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PANG Hubo. Clinical effect of bronchoscopy lavage combined with antibiotics in treatment of patients with refractory pulmonary multi-drug resistant bacteria infection[J]. Journal of Clinical Medicine in Practice, 2020, 24(3): 19-21. DOI: 10.7619/jcmp.202003006
Citation: PANG Hubo. Clinical effect of bronchoscopy lavage combined with antibiotics in treatment of patients with refractory pulmonary multi-drug resistant bacteria infection[J]. Journal of Clinical Medicine in Practice, 2020, 24(3): 19-21. DOI: 10.7619/jcmp.202003006
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Clinical effect of bronchoscopy lavage combined with antibiotics in treatment of patients with refractory pulmonary multi-drug resistant bacteria infection

  • Department of Respiratory Medicine, Zhenba County People's Hospital, Hanzhong, Shaanxi, 723600

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  • Received Date: November 09, 2019
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    • Abstract
  • Objective To investigate the clinical effect of bronchoscopy lavage combined with antibiotics in the treatment of patients with refractory pulmonary multidrug-resistant bacterial infection. Methods A total of 150 patients with refractory pulmonary multidrug-resistant bacterial infection were divided into control group(treated with antibiotics)and study group(treated with bronchoscopy lavage and antibiotic), with 75 cases in each group. The therapeutic effect, application time of antibiotics, hospitalization time, incidence of adverse reactions and bacterial negative conversion rate were compared between the two groups. Results The overall effective rate of treatment was 98.67% in the study group, which was significantly higher than 88.00% in the control group(P < 0.05). The application time of antibiotics and hospitalization time in the study group were significantly shorter than those in the control group(P < 0.05). The incidence rate of adverse reactions was 1.33% in the study group, which was significantly lower than 10.67% in the control group(P < 0.05). The bacterial negative conversion rate was 97.33 in the study group, which was significantly higher than 85.33% in the control group(P < 0.05). Conclusion Bronchoscope lavage combined with antibiotics can be used as the first choice for the treatment of patients with refractory pulmonary multidrug-resistant bacterial infection.
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  • 朝晖, 谢艳萍, 陈志冬, 等. 纤维支气管镜联合肺泡灌洗术治疗重症肺部感染患者的临床疗效[J]. 中华医院感染学杂志, 2018, 28(3): 364-366

    , 397.
    吴琳, 张苏宁. 支气管镜下肺泡灌洗并抗生素灌注辅助治疗肺癌术后肺部感染效果观察[J]. 山东医药, 2017, 57(16): 91-93.
    黄坡, 赵国桢, 陈奕杉, 等. 《中医药单用/联合抗生素治疗常见感染性疾病临床实践指南·脓毒症》解读与展望[J]. 中国中药杂志, 2018, 43(24): 4782-4785.
    陈伟文, 郭伟峰, 徐萌, 等. 矽肺病患者肺部局部感染后抗感染与支气管灌洗治疗对肺通气功能及疗效的分析[J]. 中华医院感染学杂志, 2018, 28(1): 32-36.
    张如瑞, 赵静, 张菊, 等. 纤维支气管镜灌洗在机械通气患者肺部感染中的应用价值及对炎性因子的影响[J]. 中华医院感染学杂志, 2017, 27(1): 98-100

    , 131.
    Agyepong N, Govinden U, Owusu-Ofori A, et al. Multidrug-resistant gram-negative bacterial infections in a teaching hospital in Ghana[J]. Antimicrob Resist Infect Control, 2018, 7: 37-46.
    Lavigne M C. Nonbronchoscopic methods [nonbronchoscopic bronchoalveolar lavage(BAL), mini-BAL, blinded bronchial sampling, blinded protected specimen brush] to investigate for pulmonary infections, inflammation, and cellular and molecular markers[J]. Clin Pulm Med, 2017, 24(1): 13-25.
    卢杨. 纤维支气管镜联合氨溴索肺泡灌洗对老年重症肺部感染患者肺功能及炎性反应的影响[J]. 中国老年学杂志, 2018, 38(12): 2915-2917.
    钟雪, 冯婉玉. 替加环素单药与联合方案治疗多重耐药菌感染疗效对比的系统评价[J]. 中国抗生素杂志, 2018, 43(2): 127-134.
    余舟, 刘迎, 黄建生, 等. 输尿管软镜治疗感染性肾结石合并多重耐药菌感染的疗效及安全性分析[J]. 重庆医科大学学报, 2018, 43(4): 72-75.
    马孝武, 韩学昌, 苗亚飞, 等. 双腔气管内插管单肺通气下行支气管肺泡灌洗术用于肺部感染的治疗效果研究[J]. 中华医院感染学杂志, 2017, 27(14): 3165-3168.
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