Citation: | YAN Keshi, WANG Weiwei, YU Xin, LU Dahao, DAI Chen, GAO Ju. Single versus multiple administrations of metformin in treatment of rats with ventilator-induced brain injury[J]. Journal of Clinical Medicine in Practice, 2020, 24(3): 33-35. DOI: 10.7619/jcmp.202003010 |
Quilez M E, Rodríguez-González R, Turon M, et al. Moderate peep after tracheal lipopolysaccharide instillation prevents inflammation and modifies the pattern of brain neuronal activation[J]. Shock, 2015, 44(6): 601-608.
|
Quilez M E, Fuster G, Villar J, et al. Injurious mechanical ventilation affects neuronal activation in ventilated rats[J]. Crit care, 2011, 15(3): R124.
|
Blanch L, Quintel M. Lung-brain cross talk in the critically ill[J]. Intensive Care Med, 2017, 43(4): 557-559.
|
余鑫, 米智华, 高巨. 自噬在机械通气致大鼠脑组织神经元凋亡中的作用[J]. 实用临床医药杂志, 2019, 23(8): 12-15
, 21.
|
Anisimov V N, Berstein L M, Egormin P A, et al. Metformin slows down aging and extends life span of female SHR mice[J]. Cell Cycle, 2008, 7(17): 2769-2773.
|
Knowler W C, Barrett-Connor E, Fowler S E, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin[J]. N Engl J Med, 2002, 346(6): 393-403.
|
Ng T P, Feng L, Yap K B, et al. Long-term metformin usage and cognitive function among older adults with diabetes[J]. J Alzheimers Dis, 2014, 41(1): 61-68.
|
Guo M, Mi J, Jiang Q M, et al. Metformin may produce antidepressant effects through improvement of cognitive function among depressed patients with diabetes mellitus[J]. Clin Exp Pharmacol Physiol, 2014, 41(9): 650-656.
|
Mudgal J, Nampoothiri M, Basu Mallik S, et al. Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice[J]. Inflammopharmacology, 2019, 27(5): 941-948.
|
Li W J, Chaudhari K, Shetty R, et al. Metformin alters locomotor and cognitive function and brain metabolism in normoglycemic mice[J]. Aging Dis, 2019, 10(5): 949-963.
|
Dreyfuss D, Saumon G. Ventilator-induced lung injury: lessons from experimental studies[J]. Am J Respir Crit Care Med, 1998, 157(1): 294-323.
|
Turon M, Fernández-Gonzalo S, de Haro C, et al. Mechanisms involved in brain dysfunction in mechanically ventilated critically ill patients: implications and therapeutics[J]. Ann Transl Med, 2018, 6(2): 30.
|
Pelosi P, Rocco P R. The lung and the brain: a dangerous cross-talk[J]. Crit Care, 2011, 15(3): 168.
|
Liu Y Q, Tang G H, Li Y N, et al. Metformin attenuates blood-brain barrier disruption in mice following middle cerebral artery occlusion[J]. J Neuroinflammation, 2014, 11: 177.
|
Tang G M, Yang H Y, Chen J, et al. Metformin ameliorates Sepsis-induced brain injury by inhibiting apoptosis, oxidative stress and neuroinflammation via the PI3K/Akt signaling pathway[J]. Oncotarget, 2017, 8(58): 97977-97989.
|
Ye J H, Zhu N, Sun R P, et al. Metformin inhibits chemokine expression through the AMPK/NF-κB signaling pathway[J]. J Interf Cytokine Res, 2018, 38(9): 363-369.
|