SONG Xiaoqian, ZANG Qingshu. Analgesic and sedative effects of different femoral nerve blocks of patients with hip fracture at operative position[J]. Journal of Clinical Medicine in Practice, 2020, 24(13): 91-95. DOI: 10.7619/jcmp.202013026
Citation: SONG Xiaoqian, ZANG Qingshu. Analgesic and sedative effects of different femoral nerve blocks of patients with hip fracture at operative position[J]. Journal of Clinical Medicine in Practice, 2020, 24(13): 91-95. DOI: 10.7619/jcmp.202013026

Analgesic and sedative effects of different femoral nerve blocks of patients with hip fracture at operative position

More Information
  • Received Date: April 25, 2020
  • Objective To compare the analgesic and sedative effects of dexmedetomidine combined with 0.375% ropivacaine and their use alone in femoral nerve block for patients with hip fracture at operative position. Methods Totally 150 hip fracture patients with internal fixation were randomly divided into three groups, with 50 cases in each group. Group A was treated with 0.375% ropivacaine for femoral nerve block, group B was treated with intravenous injection of 0.2 μg/kg dexmedetomidine, and group C was treated with 0.2 μg/kg dexmedetomidine combined with 0.375% ropivacaine for femoral nerve block. The mean arterial pressure(MAP), heart rate(HR)and pulse oxygen saturation(SpO2)were compared among the three groups at the time points of entering the room(T0), before taking position(T1), taking position(T2), and at the end of spinal anesthesia(T3). The analgesic effect [assessed by Visual Analogue Scale(VAS)] and sedative effect [assessed by modified Observer's Assessment of Alertness/Sedation(OAA/S)] were compared among the three groups. Adverse reactions of the three groups were recorded. Results Levels of MAP and HR at T1, T2 and T3 were significantly lower than those at T0 in the group A and the group C(P<0.05), levels of MAP and HR at T1 and T3 were significantly lower than those at T0 in the group B(P<0.05), and MAP at T2 in the group B was significantly higher than that in the group A and the group C(P<0.05). The - levels of HR at T3 in the group B and the group C were significantly lower than that in the group A (P<0.05). The levels of HR at T1 and T2 in the group C were significantly lower than that in the group A and the group B(P<0.05). The VAS scores at T2 in the group A and the group C were significantly lower than those at T0 in the same groups and at T2 in the group B(P<0.05), but there was no significant difference between the group A and the group C(P>0.05). The OAA/S scores at T1 in the group B and the group C were significantly higher than that at T0 in the same groups and at T1 in the group B(P<0.05), but there were no significant differences between the group B and the group C(P>0.05). No adverse reactions were observed in the group A, but there were 1 case(2.00%)with nausea and vomiting in the group B and 1 case(2.00%)with vertigo in the group C. There was no significant difference in the incidence of adverse reactions among the three groups(P>0.05). Conclusion Dexmedetomidine combined with 0.375% ropivacaine has exact sedative and analgesic effects at taking position in hip fracture patients with intraspinal anesthesia, which has less influence on hemodynamics and fewer adverse reactions.
  • BELOOSESKY Y, HERSHKOVITZ A, GUZ A, et al. Clinical characteristics and long-term mortality of occult hip fracture elderly patients[J]. Injury, 2010, 41(4): 343-347.
    冯明利, 沈惠良, 雍宜民, 等. 人工关节置换治疗老年脑血管意外偏瘫侧股骨颈骨折[J]. 中华骨科杂志, 2004(4): 199-202.
    BROX W T, ROBERTS K C, TAKSALI S, et al. The American academy of orthopaedic surgeons evidence-based guideline on management of hip fractures in the elderly[J]. J Bone Joint Surg Am, 2015, 97(14): 1196-1199.
    BASQUES B A, TOY J O, BOHL D D, et al. General compared with spinal anesthesia for total hip arthroplasty[J]. J Bone Joint Surg Am, 2015, 97(6): 455-461.
    祁莉英. 腰麻-硬膜外联合麻醉在高龄患者髋部手术中的应用[J]. 河北医药, 2009, 31(13): 1636-1638.
    RODGERS A, WALKER N, Schug S, et al. Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials[J]. BMJ, 2000, 321(7275): 1493-1498.
    谢丽金. 超声引导神经阻滞复合连续硬膜外麻醉在高龄患者髋部骨折手术的应用[J]. 齐齐哈尔医学院学报, 2016, 37(20): 2547-2549.
    朋立超, 吴贵龙, 仇建华. 股神经阻滞用于高龄股骨颈骨折患者超前镇痛的临床研究[J]. 中国老年学杂志, 2007, 27(4): 343-344.
    MERBOTH M K, BARNASON S. Managing pain: the fifth vital sign[J]. Nurs Clin North Am, 2000, 35(2): 375-383.
    朱红花, 方浩. 老年全髋置换术患者不同术后镇痛方法的疗效比较[J]. 老年医学与保健, 2017, 23(4): 294-297.
    张志军, 贾若, 段立鹏, 等. 髂筋膜单点与多点阻滞用于股骨颈骨折患者行椎管内麻醉摆放体位及术后镇痛效果的临床比较[J]. 北京医学, 2016, 38(10): 1111-1113.
    景颜, 陈丽, 尹芸生. 股神经阻滞和舒芬太尼用于髋部骨折麻醉前镇痛效果的比较[J]. 中国医师杂志, 2016, 18(s1): 15-18.
    JADON A, KEDIA S K, DIXIT S, et al. Comparative evaluation of femoral nerve block and intravenous fentanyl for positioning during spinal anaesthesia in surgery of femur fracture[J]. Indian J Anaesth, 2014, 58(6): 705-708.
    SANDRE A, THOMPSON C, MCLEOD S L, et al. MP033: The use of femoral nerve blocks in the emergency department for hip fracture patients[J]. CJEM, 2016, 18(S1): S77-S84.
    RIDDELL M, OSPINA M, HOLROYD-LEDUC J M. Use of femoral nerve blocks to manage hip fracture pain among older adults in the emergency department: a systematic review[J]. CJEM, 2016, 18(4): 245-252.
  • Related Articles

    [1]ZHANG Lanfang, CHEN Xu, KUAI Jun, QIN Lei, YANG Yan, CHANG Tingmin. Effect of tegafur, gimeracil and oteracil potassium combined with oxaliplatin on gastric motility-related hormones, matrix metalloproteinase-2 and matrix metalloproteinase-9 in elderly patients with gastric cancer[J]. Journal of Clinical Medicine in Practice, 2024, 28(12): 57-60, 65. DOI: 10.7619/jcmp.20241047
    [2]SUN Ling, LI Tantan, WU Xifeng, MEN Lijie, JIA Meiyan, LU Jun. Correlations of serum tissue inhibitor of metalloproteinases-1, matrix metalloproteinase-9 and vascular endothelial growth factor with degree of myelofibrosis in patients with myeloproliferative neoplasms[J]. Journal of Clinical Medicine in Practice, 2024, 28(11): 34-40. DOI: 10.7619/jcmp.20234037
    [3]YANG Bo, WANG Yanli, CUI Xiaojing. Value of combined detection of serum matrix metalloproteinase-9, soluble urokinase type plasmin activator receptor and plasmin activator inhibitor-1 in predicting prognosis of elderly patients with chronic heart failure[J]. Journal of Clinical Medicine in Practice, 2024, 28(3): 34-38. DOI: 10.7619/jcmp.20232709
    [4]SHAN Na, ZHAO Li, LIN Xiaodong. Predictive value of serum matrix metalloproteinase-9 and neurofilament light chain levels for cognitive impairment patients after first-onset ischemic stroke[J]. Journal of Clinical Medicine in Practice, 2023, 27(8): 67-70, 90. DOI: 10.7619/jcmp.20230606
    [5]YUAN Shanqi, ZHAO Hongmin, WANG Xiaoye, ZHANG Xi′an, HOU Pengfei, LIU Zhanhui. Application analysis of carotid ultrasound combined with detections of vascular endothelial growth factor, matrix metalloproteinase-9 and hypersensitive C-reactive protein in the stability of atherosclerotic plaque[J]. Journal of Clinical Medicine in Practice, 2019, 23(17): 27-29, 33. DOI: 10.7619/jcmp.201917008
    [6]ZHANG Yan, TU Jing, HUANG Hui. Study on the correlation between serum adiponectin and placental matrix metalloproteinase 9 in patients with gestational hypertension[J]. Journal of Clinical Medicine in Practice, 2017, (3): 96-98. DOI: 10.7619/jcmp.201703029
    [7]LU Jianjun, YI Liping, TUO Ya, QIAO Huizhen. Expression and clinical significance of matrix metalloproteinases-9 in tissues of endometrial carcinoma[J]. Journal of Clinical Medicine in Practice, 2014, (15): 63-65,69. DOI: 10.7619/jcmp.201415019
    [8]ZHANG Lanfang, WANG Zhanqi, LI Xiaohong, WANG Yanfei, ZHAO Shujun, HAN Kunpeng. Influence of rosuvastatin intensive therapy on serum concentration of MMP-9 and APN in acute myocardial infarction patients without percutaneous coronary intervention[J]. Journal of Clinical Medicine in Practice, 2014, (1): 12-15. DOI: 10.7619/jcmp.201401004
    [9]GAO Mingjun, QI Bo. Influence of irbesartan and amlodipine on carotid-femoral artery pulse wave velocity and serum matrix metalloproteinase-9 level in patients with primary hypertension[J]. Journal of Clinical Medicine in Practice, 2013, (23): 12-14,18. DOI: 10.7619/jcmp.201323004
    [10]ZHANG Yuhua, CAI Xiangzeng, GUO Minghe. Effects of Chuanxiongqin on serum high-sensitivity C-reactive protein, interleukin-6 and matrix metalloproteinases-9 in treating acute cerebral infarction[J]. Journal of Clinical Medicine in Practice, 2013, (17): 78-80. DOI: 10.7619/jcmp.201317026
  • Cited by

    Periodical cited type(10)

    1. 方慧孜,单海霞,王利维,陈燕. 基于思维导图的风险管理模式在新生儿窒息中的应用效果. 中国医药导报. 2024(03): 179-182 .
    2. 张姗姗,丁婧,秦好奇,张茜. 不同机械通气方案联合多巴酚丁胺治疗新生儿持续肺动脉高压的临床效果对比. 河南医学研究. 2024(17): 3140-3142 .
    3. 张耀华. 新生儿窒息复苏后持续肺动脉高压分析. 包头医学. 2023(01): 14-15+34 .
    4. 曹娜. 新生儿窒息复苏后持续肺动脉高压的影响因素. 中国医药指南. 2023(22): 110-112 .
    5. 王然,张天虎. 新生儿窒息复苏后持续性肺动脉高压的影响因素与预防干预措施. 名医. 2023(19): 39-41 .
    6. 郭朝利. 新生儿窒息原因分析及多科室协作在复苏护理中的应用研究. 中国药物与临床. 2021(05): 892-894 .
    7. 王亚红,周莲娟,朱姗姗. 新生儿窒息复苏后持续性肺动脉高压影响因素的病例对照研究. 中国妇幼保健. 2021(14): 3314-3316 .
    8. 孙丽丽. 高频振荡通气联合猪肺磷脂注射液治疗新生儿胎粪吸入综合征并肺动脉高压的效果. 河南医学研究. 2021(32): 6048-6051 .
    9. 阮敏仪,李敏许,杨勇,苏锦珍,邓皓辉. 早产儿与足月儿发生新生儿持续性肺动脉高压的特点分析. 中国医学创新. 2020(12): 157-160 .
    10. 马旭涛,赵蒙. 围生期窒息患儿颅脑超声影像学特点. 河南医学研究. 2020(29): 5504-5506 .

    Other cited types(1)

Catalog

    Article views (551) PDF downloads (6) Cited by(11)

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return