Mediating effect of depression on sleep and preoperative frailty in elderly patients with gastrointestinal cancer

XI Lijuan; WANG Daorong; FANG Fang; YUAN Haijuan

doi:10.7619/jcmp.20201747

Journal of Clinical Medicine in Practice > 2021 > 25(5): 50-54. > DOI: 10.7619/jcmp.20201747

XI Lijuan, WANG Daorong, FANG Fang, YUAN Haijuan. Mediating effect of depression on sleep and preoperative frailty in elderly patients with gastrointestinal cancer[J]. Journal of Clinical Medicine in Practice, 2021, 25(5): 50-54. DOI: 10.7619/jcmp.20201747

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Mediating effect of depression on sleep and preoperative frailty in elderly patients with gastrointestinal cancer

XI Lijuan^{1, 2},
WANG Daorong^{2, 3, 4, ,},
FANG Fang²,
YUAN Haijuan²

1.
School of Nursing of Yangzhou University, Yangzhou, Jiangsu, 225009
2.
Clinical Medical College of Yangzhou University, Yangzhou, Jiangsu, 225001
3.
Yangzhou University-General Surgery Institute of Yangzhou, Yangzhou, Jiangsu, 225001
4.
Northern Jiangsu People's Hospital of Jiangsu Province, Yangzhou, Jiangsu, 225001

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Received Date: December 20, 2020
Available Online: March 15, 2021
Published Date: March 14, 2021

Graphical Abstract

Abstract

Abstract

Objective To investigate the mediating role of depression in sleep and preoperative frailtyin elderly patients with gastrointestinal cancer.
Methods A total of 219 elderly patients with gastrointestinal cancer were selected by convenience sampling method. The general information questionnaire, Pittsburgh Sleep Quality Index, Patient Health Questionnaire-9 and Tilburg Frailty Indicator were used to investigate the correlations between depression as well as sleep and preoperative frailty.
Results Sleep and depression had direct positive effects on preoperative frailty in elderly patients with gastrointestinal cancer (β=0.326, 0.179, t=3.905, 1.977, P < 0.05); depression partially mediated in sleep and preoperative frailty (β=0.179, VAF=47.97%, P=0.043).
Conclusion Depression and sleep are closely related to preoperative frailty, and the latter can directly affect preoperative frailty, or indirectly affect the occurrence of preoperative frailty through depression. Medical staff should pay attention to the evaluation and treatment of sleep quality and depression of elderly patients before operation. For patients with poor preoperative sleep quality and difficulty in improvement, we can alleviate the preoperative depression to reduce the incidence of preoperative frailty.
- sleep,
- depression,
- preoperative frailty,
- mediating effect

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References (40)

References

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Mediating effect of depression on sleep and preoperative frailty in elderly patients with gastrointestinal cancer