Analysis on coagulation indexes, biochemical indexes and occurrence of venous thrombosis in patients with heart failure and atrial fibrillation

ZHOU Lei; GAO Zhanqiang

doi:10.7619/jcmp.202018014

Journal of Clinical Medicine in Practice > 2020 > 24(18): 50-53. > DOI: 10.7619/jcmp.202018014

ZHOU Lei, GAO Zhanqiang. Analysis on coagulation indexes, biochemical indexes and occurrence of venous thrombosis in patients with heart failure and atrial fibrillation[J]. Journal of Clinical Medicine in Practice, 2020, 24(18): 50-53. DOI: 10.7619/jcmp.202018014

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Analysis on coagulation indexes, biochemical indexes and occurrence of venous thrombosis in patients with heart failure and atrial fibrillation

ZHOU Lei¹,
GAO Zhanqiang^2, ,

1. Department of Cardiology, Shangluo City Central Hospital in Shaanxi Province, Shangluo, Shaanxi, 726000;
2. 120 First Aid Station, People's Hospital of Yan'an City in Shaanxi Province, Yan'an, Shaanxi, 716000

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Received Date: July 10, 2020

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Abstract

Abstract

Objective To analyze the coagulation indexes, biochemical indexes and occurrence of venous thrombosis in patients with heart failure and atrial fibrillation. Methods A total of 86 patients with chronic heart failure were selected and divided into control group(heart failure group)and study group(heart failure combined with atrial fibrillation group)according to whether they were complicated with atrial fibrillation. Cardiac function grading and coagulation indicators such as prothrombin time(PT), activated partial thromboplastin time(APTT), D-dimer were compared between the two groups, and biochemical indicators such as hematocrit(Hct)and C-reactive protein(CRP), and brain natriuretic peptide(BNP)were compared. Besides, the incidence of venous thrombosis in both groups was compared. Results There was no significant difference in ratio of patients with grade Ⅱ of heart function between the two groups(P>0.05); the study group had lower ratio of patients with heart function grade Ⅲ than the control group, and higher ratio of patients with heart function grade Ⅳ than the control group(P<0.05); The levels of PT, APTT and D-dimer in the study group were higher than those in the control group, and the differences were statistically significant(P<0.05). The Hct, CRP and BNP levels of the study group were significantly higher than those of the control group(P<0.05). The incidence of venous thrombosis in the study group was 34.88%, which was significantly higher than 16.28% in the control group(P<0.05). Conclusion The incidence - of venous thrombosis, levels of coagulation indicators and biochemical indicators are higher in patientswith heart failure and atrial fibrillation compared to those with heart failure. Therefore, sufficient attention should be paid during clinical treatment.
- heart failure,
- atrial fibrillation,
- coagulation indicators,
- biochemical indicators,
- venous thrombosis,
- heart function

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References

严毓勤, 朱雅琴, 周龙女, 等. 不同类型心力衰竭合并心房颤动的临床特点及心脏结构变化[J]. 中国临床保健杂志, 2019, 22(2): 247-250.

徐亮, 陈燕春, 殷云杰, 等. 血清Lp-PLA2在心房颤动并心力衰竭患者体内的表达及其临床价值[J]. 重庆医学, 2019, 48(6): 980-982

, 986.

李彦明, 何瑞利, 钟晓鸣, 等. 房颤患者血清CICP、PICP、BNP、AngⅡ水平与心功能的相关性[J]. 重庆医学, 2019, 48(4): 688-690.

赵小奎, 孙玉梅, 杨莉. 阿哌沙班与利伐沙班用于心衰合并房颤抗凝治疗的效果对比[J]. 解放军预防医学杂志, 2019, 37(2): 163-164.

何燕红, 马少宾, 高盛富, 等. D-D对急性左心衰伴房颤患者近期心血管事件发生的相关性分析[J]. 中国实用医药, 2018, 13(36): 21-23.

孙腾飞, 项晓觉, 王品晓. 慢性心力衰竭合并房颤患者行心脏再同步化治疗的预后观察[J]. 中国地方病防治杂志, 2018, 33(6): 670-671.

宋金萍, 卢佩佩, 王昌敏, 等. 慢性心衰患者血管性血友病因子活性及其基因多态性的相关性研究[J]. 新疆医科大学学报, 2018, 41(9): 1111-1116.

刘红春, 宋金萍, 王昌敏. 心衰与心衰合并房颤患者静脉血栓发生率的对比研究[J]. 新疆医学, 2018, 48(7): 694-697.

康文娥, 张玉林. 凝血功能指标与老年心力衰竭合并重症肺炎病人预后的相关性分析[J]. 实用老年医学, 2018, 32(6): 560-562

, 567.

杨吉军, 谢礼, 桂培根, 等. 房颤对急性缺血性脑卒中严重程度和早期死亡的影响[J]. 中南医学科学杂志, 2017, 45(3): 263-265.

冯广迅, 杨艳敏, 朱俊, 等. 心房颤动伴或不伴心力衰竭患者的死亡危险因素分析[J]. 中国循环杂志, 2018, 33(2): 161-165.

冯所远. 慢性心衰患者标准化“金三角”治疗前后凝血功能的监测[J]. 血栓与止血学, 2018, 24(1): 65-66

, 69.

卢红艳, 宁伟明, 苏新养. 血清CRP、Fib及NT-proBNP对慢性房颤并发早期心衰的诊断价值[J]. 海南医学, 2017, 28(8): 1271-1273.

柳菲, 王丽, 张修泽, 等. 心房颤动合并慢性心力衰竭患者的相关因素分析[J]. 吉林医学, 2017, 38(8): 1498-1499.

李曼, 温冬梅, 王伟佳, 等. NT-proBNP水平对急性心力衰竭患者近期预后的评估价值[J]. 检验医学与临床, 2017, 14(12): 1720-1722

, 1725.

孙卫国, 姬富才, 罗玉荣. 螺内酯对慢性心衰伴房颤患者血清NT-pro BNP水平与运动耐力的影响[J]. 哈尔滨医药, 2017, 37(3): 249-250.

张旭, 刘宇, 姜胜利. 血浆钠尿肽水平与阵发性房颤发生的相关性研究[J]. 中国体外循环杂志, 2017, 15(2): 92-95.

刘静, 王菲. 慢性心衰抗凝干预对心电图、凝血功能的影响[J]. 血栓与止血学, 2017, 23(1): 98-101.

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