Effect of high-intensity exercise during pregnancy on maternal and neonatal outcomes: A Meta-analysis

ZHU Yuting; CHEN Ying; WANG Xinxin; TIAN Miao; KONG Xiang; WANG Yan

doi:10.7619/jcmp.20210051

Journal of Clinical Medicine in Practice > 2021 > 25(6): 97-105. > DOI: 10.7619/jcmp.20210051

ZHU Yuting, CHEN Ying, WANG Xinxin, TIAN Miao, KONG Xiang, WANG Yan. Effect of high-intensity exercise during pregnancy on maternal and neonatal outcomes: A Meta-analysis[J]. Journal of Clinical Medicine in Practice, 2021, 25(6): 97-105. DOI: 10.7619/jcmp.20210051

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Effect of high-intensity exercise during pregnancy on maternal and neonatal outcomes: A Meta-analysis

ZHU Yuting¹,
CHEN Ying¹,
WANG Xinxin¹,
TIAN Miao¹,
KONG Xiang^{2, 3, ,},
WANG Yan^{1, 2}

1.
College of Nursing, Yangzhou University, Yangzhou, Jiangsu, 225001
2.
Department of Obstetrics, Clinical Medical College of Yangzhou University, Subei People's Hospital, Yangzhou, Jiangsu, 225001
3.
Medical College of Yangzhou University, Yangzhou, Jiangsu, 225001

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Received Date: January 03, 2021
Available Online: April 08, 2021
Published Date: March 27, 2021

Graphical Abstract

Abstract

Abstract

Objective To evaluate the effect of high-intensity exercise during pregnancy on maternal and neonatal outcomes by a Meta-analysis.
Methods Computer retrieval of the databases such as PubMed, Cochrane Library, Embase, Chinese Biomedical Literature (CBM) database, Chinese National Knowledge Infrastructure (CNKI), Wanfang database and Weipu Journal Resource Integration Service Platform was performed to search randomized controlled studies and cohort studies on high intensity exercise during pregnancy up to November 20, 2020. The statistical analysis was performed by Rev Man5.3.
Results A total of 17 studies were included with 31 747 pregnant women, including 7 randomized controlled studies and 10 cohort studies. The results of Meta-analysis showed that high-intensity exercise was able to effectively reduce the risks of fetal macrosomia (OR=0.49, 95%CI, 0.25 to 0.94, P=0.03) and not increase low birth weight (OR=1.10, 95%CI, 0.86 to 1.40, P=0.46), and increase the 1 and 5 min Apgar scores after birth (MD=0.11, 95%CI, 0.01 to 0.21, P=0.03; MD=0.11, 95%CI was 0.01 to 0.21, P=0.02).
Conclusion High-intensity exercise during pregnancy may be safe to a certain extent, which can reduce some adverse perinatal outcomes and shorten the duration of hospital stays for pregnant women. However, large-scale, multi-center and high-quality studies are still needed to confirm the influence of high-intensity exercise on abortion and stillbirths or other types of adverse events.
- high-intensity exercise,
- perinatal outcomes,
- Meta-analysis,
- neonatal Apgar score,
- macrosomia,
- low birth weight

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References (33)

References

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Effect of high-intensity exercise during pregnancy on maternal and neonatal outcomes: A Meta-analysis