Effect of passive leg raising trial and suspended ultrafiltration on hemodialysis-related hypotension in hemodialysis patients

  Objective  To observe the effect of passive leg raising (PLR) trial and suspended ultrafiltration in patients with hemodialysis-related hypotension.

  Methods  A randomized, self-designed and crossover controlled study was adopted, and the changes of blood pressure and the target of ultrafiltration after PLR and suspended ultrafiltration were recorded and compared in 52 patients with hemodialysis-related hypotension.

  Results  There were no significant differences in systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate before implementation of PLR and suspended ultrafiltration between the two groups (P>0.05). When hypotension occurred, PLR and suspended ultrafiltration were able to increase hypertension, and SBP significantly increased at 10 minutes after implementation (P < 0.05). When PLR was used for 10, 20 and 30 min, the DBP significantly increased (P < 0.05 or P < 0.01), and suspended ultrafiltration has no effect on DBP. PLR and suspended ultrafiltration were close to complete the goal of net dehydration in hemodialysis, but the actual ultrafiltration volume was significantly less than the preset ultrafiltration volume (P < 0.05).

  Conclusion  When hypotension occurs in hemodialysis patients, PLR and suspended ultrafiltration can increase blood pressure. PLR can not only increase blood pressure, but also achieve the target ultrafiltration volume.