HU Changqing, LI Bin, WANG Lihong, ZHANG Lei, HE Ping, ZHEN Na. Analysis in risk factors of catheter-related infection after peripherally inserted central catheterization in patients with chemotherapy for peripheral lung cancer[J]. Journal of Clinical Medicine in Practice, 2022, 26(15): 40-44. DOI: 10.7619/jcmp.20220461
Citation: HU Changqing, LI Bin, WANG Lihong, ZHANG Lei, HE Ping, ZHEN Na. Analysis in risk factors of catheter-related infection after peripherally inserted central catheterization in patients with chemotherapy for peripheral lung cancer[J]. Journal of Clinical Medicine in Practice, 2022, 26(15): 40-44. DOI: 10.7619/jcmp.20220461

Analysis in risk factors of catheter-related infection after peripherally inserted central catheterization in patients with chemotherapy for peripheral lung cancer

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  • Received Date: February 15, 2022
  • Available Online: August 22, 2022
  • Objective 

    To explore the risk factors of catheter-related infection (CRI) after peripherally inserted central catheterization (PICC) in patients with chemotherapy for peripheral lung cancer.

    Methods 

    A total of 450 adult patients with peripheral lung cancer in Hengshui City People's Hospital of Hebei Province from April 2017 to December 2020 were selected as research objects. Among them, 32 patients with CRI after PICC (27 cases of local infection and 5 cases of blood flow infection) were selected as CRI group, and 96 age-matched uninfected patients were selected as control group. The self-made PICC catheter maintenance record book was used to record the relevant diagnosis and treatment information of patients, including gender, body mass, age, indwelling time of PICC catheter and number of catheter puncture. Univariate analysis and multivariate Logistic regression analysis were used to explore the relevant risk factors of CRI.

    Results 

    There were significant differences in stages of lung cancer, nutritional status, indwelling time of PICC catheter, number of repeated PICC catheter puncture, range of motion of limbs on puncture side, frequency of chemotherapy administration and condition of complicating diabetes between the CRI group and the control group (P < 0.01). Multivariate Logistic regression analysis showed that the risk factors of CRI were frequency of chemotherapy administration (OR=6.386), PICC catheter displacement (OR=2.512) and complicating basic diseases such as diabetes (OR=3.362).

    Conclusion 

    There are many risk factors for CRI after PICC in patients with chemotherapy for peripheral lung cancer, such as the number of repeated catheter puncture, indwelling time of catheter, catheter displacement, and frequency of chemotherapy administration and complicating basic diseases such as diabetes. Targeted nursing intervention should be used in clinical nursing to reduce the incidence of CRI and prolong the survival of tumor patients.

  • [1]
    赫捷, 李霓, 陈万青, 等. 中国肺癌筛查与早诊早治指南(2021, 北京)[J]. 中国肿瘤, 2021, 30(2): 81-111. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHLU202102001.htm
    [2]
    肖攀, 蒲玉红, 黄星辉, 等. 2015年攀枝花市仁和区居民恶性肿瘤病例分析[J]. 预防医学情报杂志, 2018, 34(4): 466-469. https://www.cnki.com.cn/Article/CJFDTOTAL-YFYX201804018.htm
    [3]
    王平飞, 王廷杰, 李红兵, 等. 农民石工肺部疾病的临床特征和支气管镜下表现分析[J]. 预防医学情报杂志, 2017, 33(10): 960-964. https://www.cnki.com.cn/Article/CJFDTOTAL-YFYX201710002.htm
    [4]
    李晓锋, 张冠军, 汪园园, 等. 非小细胞肺癌EGFR、ALK和ROS1基因联合检测及突变共存分析[J]. 分子诊断与治疗杂志, 2018, 10(6): 378-384. doi: 10.3969/j.issn.1674-6929.2018.06.005
    [5]
    KAREAGA M M, URBIETA-MACAZAGA N, SANCHEZ-VIECO C, et al. Permanent pleural catheter (PPC) for malignant pleural effusion (PE) in advanced non-small cell lung cancer (NSCLC)[J]. Ann Oncol, 2019, 30: 63.
    [6]
    郑心子, 程美玉, 李娜. LncRNA-HOTAIR与肿瘤侵袭转移[J]. 医学分子生物学杂志, 2018, 15(4): 242-247. doi: 10.3870/j.issn.1672-8009.2018.04.011
    [7]
    陈康, 翟爱东, 努尔兰·阿汗. Smac多肽对肺腺癌耐药性的作用机制研究[J]. 临床误诊误治, 2018, 31(6): 80-83. https://www.cnki.com.cn/Article/CJFDTOTAL-LCWZ201806026.htm
    [8]
    GRAU S M S. Management of peripheral intravascular devices[J]. Enferm Clin, 2010, 20(1): 68-70. doi: 10.1016/j.enfcli.2009.12.007
    [9]
    LI H F. Analysis of high risk factors of PICC related infection and nursing countermeasures[J]. Electronic Journal of Clinical Medicine Literature, 2018, 5(82): 127.
    [10]
    周福明. 2016年成都市新都区恶性肿瘤发病死亡分析[J]. 职业卫生与病伤, 2017, 32(4): 228-231. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYWB201704013.htm
    [11]
    王建, 陈小芳, 钟训富, 等. 2010-2014年彭州市户籍人口恶性肿瘤发病与死亡分析[J]. 职业卫生与病伤, 2017, 32(6): 345-350. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYWB201706008.htm
    [12]
    詹先进, 郑大伟. CT增强扫描技术在周围型肺癌淋巴结转移的诊断研究[J]. 中国CT和MRI杂志, 2017, 15(10): 46-48, 80. https://www.cnki.com.cn/Article/CJFDTOTAL-CTMR201710015.htm
    [13]
    TAN J L, ZHAN A R. Risk factors of unplanned extubation of indwelling PICC catheter in 212 cancer patients[J]. Journal of Practical Clinical Nursing, 2019, 4(49): 102-102.
    [14]
    LIU Z W, ZHOU W X. Risk factors analysis and nursing countermeasures of PICC catheter-related infection in preterm infants[J]. World Latest Medical Information Digest, 2018, 18(48): 259-260.
    [15]
    赵玉玲, 李静, 梁飞红, 等. 肿瘤患者PICC导管相关性血流感染危险因素Logistic回归分析[J]. 广西中医药大学学报, 2018, 21(4): 104-108. https://www.cnki.com.cn/Article/CJFDTOTAL-GSZB201804039.htm
    [16]
    GRAU D, CLARIVET B, LOTTHÉ A, et al. Complications with peripherally inserted central catheters (PICCs) used in hospitalized patients and outpatients: a prospective cohort study[J]. Antimicrob Resist Infect Control, 2017, 6: 18.
    [17]
    BERTOGLIO S, FACCINI B, LALLI L, et al. Peripherally inserted central catheters (PICCs) in cancer patients under chemotherapy: a prospective study on the incidence of complications and overall failures[J]. J Surg Oncol, 2016, 113(6): 708-714.
    [18]
    ZHANG Q N, QIAN X J, CHEN J. Risk factors and Countermeasures of catheter-related bloodstream infection in ICU[J]. Chinese Hospital Statistics, 2019, 26(5): 331-333.
    [19]
    WU L N. Factor analysis and nursing countermeasures of PICC catheter-related infection in tumor patients[J]. Electronic Journal of Clinical Medicine Literature, 2018, 5(A3): 135-135.
    [20]
    张畅英. 肿瘤患者经外周静脉置入中心静脉导管相关性感染的危险因素及护理对策[J]. 中国全科医学, 2017, 20(S1): 177-179. https://www.cnki.com.cn/Article/CJFDTOTAL-QKYX2017S1066.htm
    [21]
    谢华. 肿瘤患者PlCC导管相关性感染的危险因素及预防对策[J]. 医学美学美容, 2019, 28(12): 50. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHYY201118025.htm
    [22]
    PAN Y J, ZHANG S L, LIU A X. Risk factors and prevention strategies of PICC catheter-related infection in cancer chemotherapy patients at home[J]. Zhejiang Medical Journal, 2019, 41(6): 110-113.
    [23]
    LI N, XIE S W, CHEN Y M. Risk factors analysis and nursing countermeasures of neonatal PICC catheter related infection[J]. Chinese and Foreign Women's Health Research, 2018, 25(19): 23-24.
    [24]
    吴娟, 杜娟, 刘艳琼, 等. 同期放化疗肿瘤患者PICC导管相关性感染因素分析与护理对策[J]. 全科口腔医学电子杂志, 2018, 5(36): 171-171, 173. https://www.cnki.com.cn/Article/CJFDTOTAL-QKKQ201836115.htm
    [25]
    俞素琴. 肿瘤患者PICC相关感染危险因素与护理措施[J]. 中医药管理杂志, 2017, 25(19): 139-141. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYYG201719074.htm
    [26]
    邵彩霞, 贾俊格, 洪敏. PICC护理过程发生感染的危险因素及预防措施[J]. 首都食品与医药, 2018, 25(7): 69-70. https://www.cnki.com.cn/Article/CJFDTOTAL-YYSD201807057.htm
    [27]
    张晓. PICC护理过程发生感染的危险因素及预防措施[J]. 人人健康, 2018(24): 287. https://www.cnki.com.cn/Article/CJFDTOTAL-RRJK201824283.htm
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