Application value of a new predictive scoring system for fatty pancreas based on endoscopic ultrasound diagnosis

LUO Xiaoyan; WANG Yuanzhi; YU Xiaoping; TU Xiamin; PAN Yang; LU Guotao; WANG Dan; HU Lianghao; XIAO Weiming

doi:10.7619/jcmp.20222448

Journal of Clinical Medicine in Practice > 2022 > 26(20): 1-4, 9. > DOI: 10.7619/jcmp.20222448

LUO Xiaoyan, WANG Yuanzhi, YU Xiaoping, TU Xiamin, PAN Yang, LU Guotao, WANG Dan, HU Lianghao, XIAO Weiming. Application value of a new predictive scoring system for fatty pancreas based on endoscopic ultrasound diagnosis[J]. Journal of Clinical Medicine in Practice, 2022, 26(20): 1-4, 9. DOI: 10.7619/jcmp.20222448

Citation:

PDF (1231 KB)

Application value of a new predictive scoring system for fatty pancreas based on endoscopic ultrasound diagnosis

LUO Xiaoyan¹,
WANG Yuanzhi^{2, 4},
YU Xiaoping^{4, 5},
TU Xiamin³,
PAN Yang³,
LU Guotao^{2, 3, 4},
WANG Dan⁶,
HU Lianghao⁶,
XIAO Weiming^{2, 3, 4, ,}

1.
Dalian Medical University, Dalian, Liaoning, 116044
2.
Pancreatic Center of Gastroenterology, Yangzhou University Affiliated Hospital, Yangzhou, Jiangsu, 225000
3.
Yangzhou University, Yangzhou, Jiangsu, 225000
4.
Yangzhou Key Laboratory of Pancreas in Jiangsu Province, Yangzhou, Jiangsu, 225000
5.
Health Management Centre, Yangzhou University Affiliated Hospital, Yangzhou, Jiangsu, 225000
6.
Department of Gastroenterology, Changhai Hospital of the Second Military Medical University, Shanghai, 200433

More Information

Received Date: August 09, 2020
Available Online: November 03, 2022

Graphical Abstract

Abstract

Abstract

Objective
To explore the feasibility of a new scoring system for the clinical diagnosis of the fatty pancreas(FP).
Methods
From April 2021 to June 2022, 55 patients who underwent endoscopic ultrasound (EUS) diagnosis in the Gastroenterology Center of the Affiliated Hospital of Yangzhou University were selected as research objects. The patients were divided into FP group and non-FP group by endoscopic ultrasound. The general data and biochemical parameters of the two groups were compared. Fatty liver, hypertriglyceridemia and abdominal obesity were used to be improved scoring system. Receiver operating characteristic (ROC) curve was used to evaluate the feasibility of the new improved scoring system in predicting FP.
Results
A total of 55 subjects were included, including 20 in the FP group and 35 in the non-FP group. The abdominal circumference, body mass index (BMI), proportion of hyperlipidemia and prevalence of fatty liver in the FP group were significantly more or higher than those in the non-FP group(P < 0.05). Triglyceride, alanine aminotransferase, aspartate aminotransferase in the FP group were significantly higher than those in the non-FP group, and high-density lipoprotein was significantly lower than that in the non-FP group (P < 0.05). The average number of FP combined with metabolic syndrome parameters and the proportion of the number of metabolic syndrome parameters ≥ 3 in the FP group were significantly more or higher than those in the non-FP group (P < 0.05). After improvement, the efficiency of the new scoring system in predicting FP was significantly improved (AUC increased from 0.651 to 0.731).
Conclusion
The improved scoring system can be used as a simple tool to predict FP in clinical work.
- endoscopic ultrasonography,
- fatty pancreas,
- metabolic syndrome,
- new scoring system

FullText(HTML)

References (19)

References

[1]	WAGNER R, ECKSTEIN S S, YAMAZAKI H, et al. Metabolic implications of pancreatic fat accumulation[J]. Nat Rev Endocrinol, 2022, 18(1): 43-54. doi: 10.1038/s41574-021-00573-3
[2]	PEZZILLI R, CALCULLI L. Pancreatic steatosis: is it related to either obesity or diabetes mellitus?[J]. World J Diabetes, 2014, 5(4): 415-419. doi: 10.4239/wjd.v5.i4.415
[3]	ZHOU J, LI M L, ZHANG D D, et al. The correlation between pancreatic steatosis and metabolic syndrome in a Chinese population[J]. Pancreatology, 2016, 16(4): 578-583. doi: 10.1016/j.pan.2016.03.008
[4]	HOOGENBOOM S A, BOLAN C W, CHUPRIN A, et al. Pancreatic steatosis on computed tomography is an early imaging feature of pre-diagnostic pancreatic cancer: a preliminary study in overweight patients[J]. Pancreatology, 2021, 21(2): 428-433. doi: 10.1016/j.pan.2021.01.003
[5]	SEPE P S, OHRI A, SANAKA S, et al. A prospective evaluation of fatty pancreas by using EUS[J]. Gastrointest Endosc, 2011, 73(5): 987-993. doi: 10.1016/j.gie.2011.01.015
[6]	KIM J, ALBAKHEET S S, HAN K, et al. Quantitative MRI assessment of pancreatic steatosis using proton density fat fraction in pediatric obesity[J]. Korean J Radiol, 2021, 22(11): 1886-1893. doi: 10.3348/kjr.2020.1343
[7]	TAYLOR R, BARNES A C. Translating aetiological insight into sustainable management of type 2 diabetes[J]. Diabetologia, 2018, 61(2): 273-283. doi: 10.1007/s00125-017-4504-z
[8]	KHOURY T, MARI A, SBEIT W. A novel clinical score predicting the presence of fatty pancreas[J]. J Clin Med, 2021, 10(24): 5843. doi: 10.3390/jcm10245843
[9]	WANG C Y, OU H Y, CHEN M F, et al. Enigmatic ectopic fat: prevalence of nonalcoholic fatty pancreas disease and its associated factors in a Chinese population[J]. J Am Heart Assoc, 2014, 3(1): e000297. doi: 10.1161/JAHA.113.000297
[10]	SINGH R G, YOON H D, WU L M, et al. Ectopic fat accumulation in the pancreas and its clinical relevance: a systematic review, meta-analysis, and meta-regression[J]. Metabolism, 2017, 69: 1-13. doi: 10.1016/j.metabol.2016.12.012
[11]	ZHOU C M, ZHAN L, YUAN J, et al. Comparison of visceral, general and central obesity indices in the prediction of metabolic syndrome in maintenance hemodialysis patients[J]. Eat Weight Disord, 2020, 25(3): 727-734. doi: 10.1007/s40519-019-00678-9
[12]	TIAN T, ZHANG J X, ZHU Q R, et al. Predicting value of five anthropometric measures in metabolic syndrome among Jiangsu Province, China[J]. BMC Public Health, 2020, 20(1): 1317. doi: 10.1186/s12889-020-09423-9
[13]	ZHANG F L, REN J X, ZHANG P, et al. Strong association of waist circumference (WC), body mass index (BMI), waist-to-height ratio (WHtR), and waist-to-hip ratio (WHR) with diabetes: a population-based cross-sectional study in Jilin Province, China[J]. J Diabetes Res, 2021, 2021: 8812431.
[14]	PINNICK K E, COLLINS S C, LONDOS C, et al. Pancreatic ectopic fat is characterized by adipocyte infiltration and altered lipid composition[J]. Obesity (Silver Spring), 2008, 16(3): 522-530. doi: 10.1038/oby.2007.110
[15]	JIALAL I, ADAMS-HUET B. Comparison of the triglyceride-waist circumference and the C-reactive protein-waist circumference indices in nascent metabolic syndrome[J]. Int J Physiol Pathophysiol Pharmacol, 2021, 13(5): 126-131.
[16]	KOÇ U, TAYDAȘ O. Evaluation of pancreatic steatosis prevalence and anthropometric measurements using non-contrast computed tomography[J]. Turk J Gastroenterol, 2020, 31(9): 640-648. doi: 10.5152/tjg.2020.19434
[17]	ZHANG Y, LI J, XU Y Q. Association of incidence between pancreatic adipose infiltration and metabolic syndrome: a literature review and meta-analysis[J]. Comput Math Methods Med, 2021, 2021: 5747558.
[18]	SINGH R G, YOON H D, POPPITT S D, et al. Ectopic fat accumulation in the pancreas and its biomarkers: a systematic review and meta-analysis[J]. Diabetes Metab Res Rev, 2017, 33(8): 1-13.
[19]	李鑫, 胡梦琪, 郎艳飞, 等. 超声内镜对脂肪胰的诊断及相关临床因素分析[J]. 中南医学科学杂志, 2020, 48(1): 72-75. https://www.cnki.com.cn/Article/CJFDTOTAL-HYYY202001019.htm

Cited By

Cited by

Periodical cited type(26)

1.	赖惠菲，赖亮，李小斌，许春华. 输尿管软镜碎石术治疗直径小于2cm肾结石后应用结石通胶囊联合盐酸坦索罗辛临床观察. 实用中医药杂志. 2024(01): 85-87 .
2.	曹滨，何永欢，丁勇. 经皮肾镜碎石取石术与输尿管软镜钬激光碎石术治疗肾结石的效果观察. 大医生. 2024(05): 56-58 .
3.	谢奕彪，崔小健. 输尿管软镜碎石取石术治疗直径≤2 cm的肾结石的疗效及对肾功能和炎症相关指标的影响. 中国内镜杂志. 2024(05): 75-81 .
4.	聂武刚. 输尿管软镜钬激光碎石术对上尿路结石患者结石清除效果及应激指标的影响. 医学信息. 2024(12): 115-118 .
5.	张恒志. 经皮肾镜碎石取石术对肾结石患者肾功能指标、并发症发生率及生活质量的影响. 中国医学创新. 2024(17): 33-37 .
6.	方晖东，刘俊峰，潘佐，乔璐，刘智超. 输尿管软镜碎石术在2 cm左右肾结石中的应用价值. 泌尿外科杂志(电子版). 2024(03): 17-20 .
7.	刘国政. 不同碎石术对上尿路结石患者结石逃逸和肾功能的影响. 中国激光医学杂志. 2024(05): 263-268 .
8.	黎德林，黄恒海，陈值权，龙勇新，林圣皓. 输尿管软镜联合可视穿刺F4.8超微通道经皮肾镜治疗肾多发性结石的临床研究. 中国医药科学. 2023(01): 187-191 .
9.	王培龙，李笑然，何藄琪，马腾，符小宝，包军胜，杨宁强. 单通道经皮肾镜取石术联合输尿管软镜与输尿管软镜钬激光碎石术治疗复杂性肾结石的效果比较. 实用临床医药杂志. 2023(02): 101-104+112 . 本站查看
10.	霍建武，张金刚. 输尿管软镜钬激光碎石术对直径2～3 cm肾结石患者肾功能的影响研究. 中国医药科学. 2023(12): 145-148 .
11.	郝强，焦宗久，牛忠涛，石丽佳，张淑敬. mPCNL与RIRS对直径>2cm肾结石患者肾功能及氧化应激指标的影响. 临床误诊误治. 2023(06): 103-107 .
12.	陈王超. 输尿管导管与斑马导丝对URL中输尿管损伤的预防效果. 淮海医药. 2023(04): 383-386 .
13.	张小军，张立国，高海洋，刘健，曹凤宏，张金存，王勇，高伟兴. 输尿管软镜碎石术联合叶金排石胶囊治疗直径小于2 cm肾结石临床疗效分析. 中华中医药学刊. 2022(01): 212-215 .
14.	张家杰，徐方明，潘高宇，葛波，肖宁，韦开禄. 硕通镜钬激光碎石术与微通道经皮肾镜碎石术治疗输尿管上段结石(<2cm)疗效及应激反应指标变化的比较. 中国性科学. 2022(01): 23-26 .
15.	谢强. 输尿管镜下钬激光与气压弹道碎石术治疗输尿管对比研究. 甘肃医药. 2022(02): 137-138+143 .
16.	冯德胜，张亚旗，周东方. 超微经皮肾镜取石术与输尿管软镜碎石取石术治疗男性长径≥2.0 cm肾结石的效果比较. 中国实用医刊. 2022(07): 17-20 .
17.	林燕娇. 疼痛护理干预对急诊肾结石患者疼痛程度、生理应激反应及睡眠质量的影响分析. 中外医疗. 2022(05): 154-157+162 .
18.	刘旭东，杜勇，李志远，何正宇. 复杂肾结石患者行经皮肾镜、输尿管软镜单一及联合治疗效果、炎症指标及安全性对比研究. 实用医院临床杂志. 2022(04): 102-105 .
19.	卓兴宇，张云，陈从其. 经尿道输尿管软镜碎石术治疗肾结石的临床研究. 实用中西医结合临床. 2022(15): 63-65+81 .
20.	潘中义，张世清，熊玉龙. 输尿管支架在输尿管软镜治疗2～3cm肾结石的疗效及对术后排石、术后排尿症状评分的影响分析. 世界复合医学. 2022(09): 119-123 .
21.	王刚，章钟，张国华，徐启鹏，汪锡兴，江金龙，潘周辉. F16微通道与标准通道经皮肾镜取石术临床疗效比较. 中国临床医生杂志. 2021(04): 469-471 .
22.	王勤军. 经皮肾镜联合输尿管软镜治疗复杂性肾结石效果观察. 实用中西医结合临床. 2021(07): 126-128 .
23.	霍自豪. 电子输尿管软镜下钬激光碎石对肾结石患者清石率、机体应激反应及Cys-C、KIM-1水平的影响. 临床医学研究与实践. 2021(28): 91-93 .
24.	朱晨迪，郑鹏毅，周真真. 输尿管硬镜负压组合式吸引鞘在肾结石患者术中的应用效果与安全性观察. 云南医药. 2021(06): 533-535+529 .
25.	陈然，潘晓明，田慷. 经输尿管软镜碎石术与经皮肾镜碎石术治疗肾结石的效果分析. 现代医学与健康研究电子杂志. 2021(24): 74-77 .
26.	高景宇，王磊，罗子靖，徐哲，张晔. 尿液白介素-6和肿瘤坏死因子-α表达水平与输尿管结石钬激光碎石术后输尿管痉挛的相关性研究. 中国医学前沿杂志(电子版). 2020(12): 76-80 .

Other cited types(0)

Get Citation

PDF

XML

Article views (206) PDF downloads (31) Cited by(26)

Turn off MathJax

Article Contents

Abstract

References

Application value of a new predictive scoring system for fatty pancreas based on endoscopic ultrasound diagnosis

Abstract

References

Cited by

Periodical cited type(26)

Other cited types(0)

Catalog

Export File

Citation

Format

Content