Advance Search
LEI Meixia, JIANG Shu, LI Chunlin, DENG Xiaoqin. Effect analysis of Tongfu Jiangqi Decoction in patients with acute exacerbation of chronic obstructive pulmonary disease[J]. Journal of Clinical Medicine in Practice, 2023, 27(7): 51-55. DOI: 10.7619/jcmp.20223309
Citation: LEI Meixia, JIANG Shu, LI Chunlin, DENG Xiaoqin. Effect analysis of Tongfu Jiangqi Decoction in patients with acute exacerbation of chronic obstructive pulmonary disease[J]. Journal of Clinical Medicine in Practice, 2023, 27(7): 51-55. DOI: 10.7619/jcmp.20223309
shu

Effect analysis of Tongfu Jiangqi Decoction in patients with acute exacerbation of chronic obstructive pulmonary disease

  • the Eight Department of Internal Medicine, Neijiang Hospital of Traditional Chinese Medicine, Neijiang, Sichuan, 641000

More Information
  • Received Date: November 06, 2022
  • Available Online: April 22, 2023
    Graphical Abstract
    • Abstract
  • Objective 

    To observe the improvement effect of Tongfu Jiangqi Decoction on blood gas and lung function in patients with acute obstructive pulmonary disease (AECOPD).

    Methods 

    A total of 160 patients with AECOPD admitted to our hospital from February 2020 to February 2022 were prospectively selected as research objects, and were divided into group A and group B by coin toss method. Finally, 86 patients in group A and 74 patients in group B were included. Both groups were given conventional western medicine treatment, and patients in group A were additionally given Tongfu Jiangqi Decoction. The clinical efficacy of the two groups was compared, and the pulmonary function[forced expiratory volume in one second (FEV1), forced vital capacity (FVC) and FEV1 percentage of predicted value (FEV1%pred)], symptom score (wheezing, cough, expectoration), coagulation function[D-Dimer (D-D), fibrinogen (Fib)], inflammatory factors[white blood cell(WBC) count, and C-reactive protein (CRP)], blood gas index including pH value, arterial partial pressure of oxygen[pa(O2)], and arterial partial pressure of carbon dioxide[pa(CO2)]before treatment and 14 days after treatment were recorded, and the incidence of adverse reactions was observed.

    Results 

    The total effective rate of group A was 96.51% (83/86), which was significantly higher than 79.73% (59/74) in the group B(P < 0.05); after 14 days of treatment, the levels of FVC, FEV1 and FEV1%pred in the two groups were significantly increased, and those in the group A were higher than those in the group B (P < 0.05); after 14 days of treatment, the scores of wheezing, cough and sputum production in the symptom scores of the two groups were significantly decreased, and the above scores of group A were lower than those of group B (P < 0.05). After 14 days of treatment, the levels of D-D and Fib in both groups were decreased, and group A was significantly lower than group B (P < 0.05). After 14 days of treatment, the levels of WBC and CRP in both groups were decreased, and group A was significantly lower than group B(P < 0.05); after 14 days of treatment, the levels of pH value and pa(O2) in both groups were increased, and pa(CO2) was reduced. The level of pa(O2) and pH value in group A were significantly higher than those in group B, and the level of pa(CO2) in group A was lower than that in group B(P < 0.05).

    Conclusion 

    The treatment effect of Tongfu Jiangqi Decoction combined with western medicine for patients with AECOPD is significant. The pulmonary function, clinical symptoms, coagulation function, inflammatory reaction and blood gas status of patients are significantly improved, and there is no obvious adverse reaction.

    • FullText(HTML)
    • References (19)
  • [1]
    CHEN L, CHEN S. Prediction of readmission in patients with acute exacerbation of chronic obstructive pulmonary disease within one year after treatment and discharge[J]. BMC Pulm Med, 2021, 21(1): 320. doi: 10.1186/s12890-021-01692-3
    [2]
    黄菲菲, 秦继山. 中老年慢性阻塞性肺疾病临床特征与病情进展的相关性[J]. 实用临床医药杂志, 2021, 25(1): 45-49, 53. doi: 10.7619/jcmp.20200227
    [3]
    MATHIOUDAKIS A G, JANSSENS W, SIVAPALAN P, et al. Acute exacerbations of chronic obstructive pulmonary disease: in search of diagnostic biomarkers and treatable traits[J]. Thorax, 2020, 75(6): 520-527. doi: 10.1136/thoraxjnl-2019-214484
    [4]
    李乐, 杨楠, 周奇, 等. 辛伐他汀辅助治疗慢性阻塞性肺疾病有效性和安全性的Meta分析[J]. 中国循证医学杂志, 2021, 21(2): 145-152. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZXZ202102004.htm
    [5]
    袁思成, 黄肖玲, 华胜毅, 等. 利用超声探测评价针刺对慢性阻塞性肺疾病急性加重期Ⅱ型呼吸衰竭患者膈肌功能的影响[J]. 中国针灸, 2021, 41(7): 703-710. doi: 10.13703/j.0255-2930.20200606-k0007
    [6]
    滕文哲, 陈虎, 石思瑶, 等. 双水平正压通气治疗慢性阻塞性肺疾病急性加重期并发Ⅱ型呼吸衰竭效果的Meta分析与试验序贯分析[J]. 中国全科医学, 2022, 25(2): 227-235. doi: 10.12114/j.issn.1007-9572.2021.01.224
    [7]
    袁梦鑫, 陈雨莎, 欧雪梅, 等. 慢性阻塞性肺疾病急性加重期肺康复研究进展[J]. 中国呼吸与危重监护杂志, 2020, 19(1): 92-95. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGHW202001029.htm
    [8]
    连乐燊, 蒋紫云, 黄佳城, 等. 加味凉膈散联合西药治疗慢性阻塞性肺疾病急性加重期60例临床研究[J]. 江苏中医药, 2020, 52(6): 28-31. https://www.cnki.com.cn/Article/CJFDTOTAL-JSZY202006010.htm
    [9]
    慢性阻塞性肺疾病急性加重(AECOPD)诊治专家组. 慢性阻塞性肺疾病急性加重(AECOPD)诊治中国专家共识(2017年更新版)[J]. 国际呼吸杂志, 2017(14): 1041-1057.
    [10]
    中华医学会, 中华医学会杂志社, 中华医学会全科医学分会, 等. 慢性阻塞性肺疾病基层诊疗指南(实践版·2018)[J]. 中华全科医师杂志, 2018, 17(11): 871-877.
    [11]
    殷晓明, 陈慧敏, 唐文娟, 等. 丹参多酚酸盐结合呼吸锻炼对老年急性加重期慢性阻塞性肺疾病合并冠心病患者疗效[J]. 实用医学杂志, 2020, 36(14): 1972-1976. https://www.cnki.com.cn/Article/CJFDTOTAL-SYYZ202014024.htm
    [12]
    梁茂新, 高天舒. 《中药新药临床研究指导原则》脏腑诸证考察与分析[J]. 中国中医基础医学杂志, 2008, 14(5): 330-331, 342. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJC200805004.htm
    [13]
    王湘云, 陈元菁, 张景熙, 等. 治疗性健康教育对老年COPD患者生理心理状况的影响[J]. 国际呼吸杂志, 2022, 42(2): 111-117.
    [14]
    胡海涛, 李自健, 胡振红, 等. BiPAP正压无创呼吸机辅助治疗老年AECOPD的临床疗效及对患者肺功能、血清炎性因子和预后指标的影响[J]. 现代生物医学进展, 2021, 21(12): 2275-2279. https://www.cnki.com.cn/Article/CJFDTOTAL-SWCX202112017.htm
    [15]
    吕侯强, 谢轩, 范素芳. 高血糖对慢性阻塞性肺疾病急性加重期患者血清炎性因子和肺功能的影响及相关性分析[J]. 临床误诊误治, 2020, 33(1): 45-49. https://www.cnki.com.cn/Article/CJFDTOTAL-LCWZ202001012.htm
    [16]
    王景莉. 中医干预方案联合振动排痰对慢性阻塞性肺疾病急性加重期患者肺功能及生活质量的影响[J]. 中国民间疗法, 2021, 29(21): 76-78. https://www.cnki.com.cn/Article/CJFDTOTAL-ZMJL202121028.htm
    [17]
    钟勇, 陈静. 中医经典方剂治疗慢性阻塞性肺疾病急性加重期研究进展[J]. 广西中医药大学学报, 2021, 24(3): 70-73. https://www.cnki.com.cn/Article/CJFDTOTAL-GSZB202103022.htm
    [18]
    符沙沙, 陈宗存, 王志峰, 等. 老年慢性阻塞性肺疾病相关肺动脉高压、高凝状态与血清脂联素、8-异前列腺素F2α的关系[J]. 实用老年医学, 2022, 36(2): 180-183. https://www.cnki.com.cn/Article/CJFDTOTAL-SYLA202202018.htm
    [19]
    林青伟, 宋景春, 余婷, 等. 创伤性肺损伤相关凝血病的预警指标及其临床价值分析[J]. 解放军医学杂志, 2021, 46(4): 367-372. https://www.cnki.com.cn/Article/CJFDTOTAL-JFJY202104008.htm
    • Related Articles

  • Related Articles

    [1]LI Xiulei, ZHU Yunhe, GUO Chen. Impacts of endoscopic cold snare polypectomy on the complete polypectomy rate and stress response in patients with small colorectal polyps[J]. Journal of Clinical Medicine in Practice, 2024, 28(1): 78-81. DOI: 10.7619/jcmp.20232711
    [2]TANG Wei, JI Feng, YUAN Lan. Effect of electroacupuncture pretreatment on postoperative stress response, intestinal mucosal function and inflammatory factor levels in patients undergoing radical gastrectomy[J]. Journal of Clinical Medicine in Practice, 2021, 25(16): 40-44. DOI: 10.7619/jcmp.20211602
    [3]ZHANG Zhian, LEI Guodong. Effect of combined spinal-epidural anesthesia versus general anesthesia on hemodynamics and stress response in patients with hip replacement[J]. Journal of Clinical Medicine in Practice, 2020, 24(13): 80-83. DOI: 10.7619/jcmp.202013023
    [4]ZHOU Qing, SHU Chang, ZHU Yunhai, YANG Bo, MENG Jun, MA Yong, ZENG Zhi. Influence of ureteroscopic lithotripsy on stress response and inflammatory indexes in patients with renal stone less than 2 cm[J]. Journal of Clinical Medicine in Practice, 2020, 24(8): 33-35. DOI: 10.7619/jcmp.202008009
    [5]WANG Yan. Influence of empathy nursing on psychological stress, pain and postoperative complications for thyroidectomy patients[J]. Journal of Clinical Medicine in Practice, 2017, (20): 75-78. DOI: 10.7619/jcmp.201720024
    [6]WANG Jianghua, CUI Yaqing. Effects of comprehensive temperature preserving nursing on intraoperative stress and complications in gynecological hysteroscopy patients[J]. Journal of Clinical Medicine in Practice, 2017, (16): 88-90,102. DOI: 10.7619/jcmp.201716028
    [7]ZHANG Yan, QIN Ling. The inhibitory effect of concerning care on stress response for patients in operation room[J]. Journal of Clinical Medicine in Practice, 2017, (10): 97-100. DOI: 10.7619/jcmp.201710030
    [8]LUO Wancui. Effect of clinical nursing pathway on perioperative stress response of patients with laparoscopic uterine flesh tumor excision[J]. Journal of Clinical Medicine in Practice, 2016, (18): 137-139,143. DOI: 10.7619/jcmp.201618044
    [9]LI Xiaojing, JI Xiaoli, QIAN Tao, ZHU Yabin, SUN Canlin. Preemptive analgesic effect of different doses of dezocine on stress response in recovery period of general anesthesia in elderly patients[J]. Journal of Clinical Medicine in Practice, 2016, (7): 75-78. DOI: 10.7619/jcmp.201607022
    [10]SUN Renbo, WANG Yaohua, SUN Fude, TANG Zuen. Effects of stellate ganglion block on the stress response and postoperative recovery in patients with gastrointestinal tumors[J]. Journal of Clinical Medicine in Practice, 2013, (21): 175-177. DOI: 10.7619/jcmp.201321059

  • Cited by

    Periodical cited type(2)

    1. 张成岗. 菌粒阴阳学说：基于“人微共生体”探讨中医阴阳学说的学术思考. 中华中医药学刊. 2023(03): 11-20+260 .
    2. 张成岗. 确保生物安全与发展生物经济的多维思考. 人民论坛·学术前沿. 2022(14): 37-46 .

    Other cited types(1)

Catalog

    Get Citation
    PDF
    XML
    Article views (151) PDF downloads (12) Cited by(3)
    Turn off MathJax
    Article Contents
    Abstract
    References
    Related Articles

    © 2020 《实用临床医药杂志》编辑部

    Address: 江苏省扬州市江阳中路136号，扬州大学江阳路北校区14号楼201室China Pos: 225009Tel: 0514-87978917、87978989、87978807

    苏公网安备 32100302010246号

    Supported by: Beijing Renhe Information Technology Co., Ltd.   Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return