Citation: | XU Yan, ZHU Chunyun. Monitoring and protection of peripheral blood cell count for nursing staffs in ward after iodine-125 implantation[J]. Journal of Clinical Medicine in Practice, 2023, 27(13): 123-126. DOI: 10.7619/jcmp.20231229 |
To explore the effect of radiation exposure after iodine-125 implantation on the blood indicators of nursing staff in wards, and to provide basis for improving the radiation protection of nursing staff.
Peripheral blood parameters of the nursing staff(experimental group) in the ward who were exposed to iodine-125 after implantation were monitored, and the blood parameters of the nursing staff(control group) in the ward without particle implantation during the same period were compared and analyzed. In addition, the results of gamma ray exposure from different angles and distances in patients after iodine-125 implantation were compared in conditions of lead shielding or lead-free shielding on the same day.
The results of the peripheral blood parameters in the experimental group were lower than those in the control group (P>0.05). Under the condition of lead-free shielding, the radiation dose measured at a distance of 100 cm from the puncture site was (10.6±2.6) uSv/h, which was close to the natural background radiation dose measured by γ-rays. Under the condition of lead shielding, the radiation dose measured at a distance of 15 cm was (10.4±2.0) uSv/h, which was close to the natural background radiation dose measured by γ-rays.
After using lead shielding, post-implantation radiation exposure from iodine-125 has no significant impact on the peripheral blood parameters of the nursing staff in the ward and can effectively reduce the safe radiation distance.
[1] |
CARDOSO R M, DE SOUZA C D, ROSTELATO M E C M, et al. Highly efficient method for production of radioactive silver seed cores for brachytherapy[J]. Appl Radiat Isot, 2017, 120: 76-81. doi: 10.1016/j.apradiso.2016.11.023
|
[2] |
WU Z Y, ZHANG J, SUN Y, et al. 125I seed implant brachytherapy-assisted surgery for treatment of mucoepidermoid carcinoma of parotid[J]. Brachytherapy, 2018, 17(4): S60.
|
[3] |
王一青, 朱林海, 林旭, 等. CT引导下125I粒子植入术对晚期肺癌及肺转移癌的治疗作用[J]. 中国肺癌杂志, 2020, 23(6): 424-428. https://www.cnki.com.cn/Article/CJFDTOTAL-FAIZ202006005.htm
|
[4] |
张楠. 碘-125放射性粒子植入治疗对肺癌化疗患者生活质量的影响[J]. 实用临床医药杂志, 2020, 24(6): 20-23. doi: 10.7619/jcmp.202006006
|
[5] |
STRZELCZYK J J, DAMILAKIS J, MARX M V, et al. Facts and controversies about radiation exposure, part 2: low-level exposures and cancer risk[J]. J Am Coll Radiol, 2007, 4(1): 32-39. doi: 10.1016/j.jacr.2006.07.010
|
[6] |
姜树坤, 王俊杰, 闫先瑞, 等. 放射性125I粒子植入患者术后24 h周围人员及床边剂量检测及年累积剂量预测[J]. 中国医学装备, 2020, 17(3): 14-18. https://www.cnki.com.cn/Article/CJFDTOTAL-YXZB202003004.htm
|
[7] |
周媛媛, 王进, 余宁乐, 等. 江苏省2 642名放射工作人员外周血淋巴细胞染色体畸变及微核率分析[J]. 职业与健康, 2016, 32(14): 1891-1893. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJK201614006.htm
|
[8] |
张俊伶, 李德冠, 路璐, 等. Vam3对辐射所致小鼠骨髓单个核细胞损伤的保护作用[J]. 中华放射医学与防护杂志, 2014(9): 676-677. https://www.cnki.com.cn/Article/CJFDTOTAL-TJYZ201401018.htm
|
[9] |
陈历赛, 段宝凤, 吴志群, 等. 125I粒子植入术后放射暴露对医护人员外周血象的影响[J]. 护理研究, 2017, 31(6): 727-728. https://www.cnki.com.cn/Article/CJFDTOTAL-SXHZ201706029.htm
|
[10] |
李思进, 高再荣. 放射性125I粒子植入治疗恶性实体肿瘤技术质量管理核医学专家共识(2019年版)[J]. 中华核医学与分子影像杂志, 2020, 40(11): 673-678.
|
[11] |
胡欢, 杨婷. 肿瘤科护理人员对125I粒子植入的放射防护知信行调查[J]. 实用临床护理学电子杂志, 2018, 3(37): 149-149, 151. https://www.cnki.com.cn/Article/CJFDTOTAL-SLHL201837121.htm
|
[12] |
SHABANI F, HASANZADEH H, EMADI A, et al. Radiation protection knowledge, attitude, and practice (KAP) in interventional radiology[J]. Oman Med J, 2018, 33(2): 141-147.
|
[13] |
国家质量监督检验检疫总局. 电离辐射防护与辐射源安全基本标准: GB 18871—2002[S]. 北京: 中国标准出版社, 2004.
|
[14] |
李蓓, 赵云. 125I粒子放射防护护理质量评价体系的建立及实践初探[J]. 当代护士: 下旬刊, 2018, 25(6): 118-121. https://www.cnki.com.cn/Article/CJFDTOTAL-DDHZ201806054.htm
|