Clinical effect of endovascular stent implantation in treatingcarotid artery stenosis in patients with ischemic cerebrovascular disease

LIU Xinhua; DENG Jianzhong; LYU Gaopeng

doi:10.7619/jcmp.20233818

Journal of Clinical Medicine in Practice > 2024 > 28(13): 87-91, 97. > DOI: 10.7619/jcmp.20233818

LIU Xinhua, DENG Jianzhong, LYU Gaopeng. Clinical effect of endovascular stent implantation in treatingcarotid artery stenosis in patients with ischemic cerebrovascular disease[J]. Journal of Clinical Medicine in Practice, 2024, 28(13): 87-91, 97. DOI: 10.7619/jcmp.20233818

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Clinical effect of endovascular stent implantation in treatingcarotid artery stenosis in patients with ischemic cerebrovascular disease

the First Department of Neurology, Anyang District Hospital of Puyang City in Henan Province, Anyang, Henan, 455000

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Received Date: November 27, 2023
Revised Date: May 02, 2024
Available Online: July 19, 2024

Graphical Abstract

Abstract

Abstract

Objective
To observe the clinical effect of endovascular stent implantation in the treatment of patients with ischemic cerebrovascular disease (ICVD) and carotid artery stenosis.
Methods
A total of 83 patients with ICVD treatment were selected and divided into observation group with 43 cases and control group with 40 cases, and the hemodynamic indicators and degree of internal carotid artery stenosis, neural markers and vascular endothelial function, degree of neurological deficits, clinical efficacy, and adverse reactions were compared between the two groups.
Results
Peak systolic velocity (PSV), end-diastolic velocity (EDV), and degree of vascular stenosis in both groups showed a downward trend after treatment, and the declines in PSV, EDV and vascular stenosis in the control group were all significantly smaller than those in the observation group (P < 0.05). After treatment, the positive pentraxin-3 (PTX-3) and neuron-specific enolase (NSE) levels in both groups decreased significantly, while functional movement disorder (FMD) and vascular endothelial growth factor (VEGF) levels increased significantly, and the PTX-3 and NSE levels in the observation group were significantly lower than those in the control group, while the VEGF and FMD levels were significantly higher (P < 0.05). After treatment, scores of the National Institutes of Health Stroke Scale (NIHSS) and the Modified Edinburgh-Scandinavian Stroke Scale (MESSS) in both groups decreased, and the decline in NIHSS score and MESSS in the control group was smaller than that in the observation group. Clinical total effective rate was 80.00% in the control group, which was significantly lower than 97.67% in the observation group (P < 0.05). The incidence of adverse reactions in the observation group was 2.33%, which was significantly lower than 22.50% in the control group (P < 0.05).
Conclusion
Endovascular stent implantation can effectively improve the clinical efficacy of ICVD patients, relieve the degree of vascular stenosis, improve cognitive function, and has higher safety.
- endovascular stent implantation,
- ischemic cerebrovascular disease,
- carotid artery stenosis,
- clinical efficacy,
- safety

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References

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Clinical effect of endovascular stent implantation in treatingcarotid artery stenosis in patients with ischemic cerebrovascular disease