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WANG Lei, LI Shutie, YUAN Na. Effects of doxophylline of different administration methods on weaning time of acute exacerbation of chronic obstructive pulmonary diseases of APACHEⅡ score[J]. Journal of Clinical Medicine in Practice, 2014, (16): 112-114. DOI: 10.7619/jcmp.201416035
Citation: WANG Lei, LI Shutie, YUAN Na. Effects of doxophylline of different administration methods on weaning time of acute exacerbation of chronic obstructive pulmonary diseases of APACHEⅡ score[J]. Journal of Clinical Medicine in Practice, 2014, (16): 112-114. DOI: 10.7619/jcmp.201416035
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Effects of doxophylline of different administration methods on weaning time of acute exacerbation of chronic obstructive pulmonary diseases of APACHEⅡ score

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  • Published Date: September 10, 2014
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  • Objective To study effects of doxophylline of different administration methods on weaning time of acute exacerbation of chronic obstructive pulmonary diseases(AECOPD)of A-PACHEⅡ score.Methods 45 patients with AECOPD treated with mechanical ventilation and successful ventilator weaning were selected.In APACHEⅡ<20 patients,13 cases with doxo-fylline by continuous pump were in continuous pump group and 11cases in intravenous drip group;In APACHEⅡ≥20 patients,there were doxofylline by continuous pump with 11 cases and Doxo-fylline by intravenous drip with 10 cases,the effect of ventilator weaning time in different A-PACHEⅡscore between doxofylline by continuous pump and intravenous drip were observed.Re-sults The ventilator weaning time of doxofylline by continuous pump and intravenous drip were compared in APACHEⅡ<20,which was statistically significant difference (P <0.05).but there was no significant difference in APACHEⅡ≥20(P >0.05).Conclusion Ventilator weaning time of AECOPD is influenced by APACHEⅡ score.Continuous pump into doxofylline can obvi-ously relieve mechanical ventilation time in APACHEⅡ<20 and improve the rate of weaning time.
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