Effect of oral administration of contraceptives on prevention of recurrence after hysteroscopic endometrial polypectomy

  Objective  To investigate the effect of oral administration of contraceptives on prevention of recurrence after hysteroscopic endometrial polypectomy.

  Methods  A total of 240 patients with endometrial polyps (EP) were randomly divided into control group (n=120) and observation group (n=120). The control group was treated with hysteroscopic endometrial polypectomy alone, and the observation group was treated with compound short-acting contraceptives after operation. The changes of hemoglobin (Hb) and endometrial thickness were observed at 3 and 6 months after operation, and menstrual improvement and EP recurrence were compared between the two groups.

  Results  The serum Hb level increased significantly, and the endometrial thickness decreased significantly at 3 and 6 months after operation (P < 0.05), and the observation group changes more significantly at 6 months after operation than the control group(P < 0.05). The rate of returning to regular menstruation at 6 months after operation in the observation group was higher, and the recurrence rate of EP was lower than that in the control group(91.67% vs. 78.33%, 4.17%vs. 14.17, P < 0.05).

  Conclusion  Oral administration of short-acting contraceptives after hysteroscopic endometrial polypectomy can increase the level of serum Hb and inhibit endometrial hyperplasia, and play a positive role in improving menstruation and prevention of EP recurrence.