Value of routine coagulation test and thrombelastography in evaluating short-term prognosis of patients with acute cerebral infarction

  Objective  To investigate the value of routine blood coagulation test and thromboelastography (TEG) in evaluating the short-term prognosis of patients with acute cerebral infarction.

  Methods  A total of 86 patients with acute cerebral infarction were divided into control group (poor prognosis) and observation group (good prognosis) according to the recurrence of cerebral infarction, with 43 cases in each group. The indexes of routine coagulation test and TEG parameters were compared in the two groups.

  Results  There were no significant differences in the levels of fibrinogen (FIB), activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT) and platelet count (PLT) in the two groups on admission (P>0.05). On admission, the formation time and reaction time of coagulation in the observation group were significantly longer, the α angle was smaller, and the maximum amplitude of clot formation was significantly lower than that in the control group (P < 0.05). After 3 months of follow-up, the maximum amplitude of observation group was significantly lower than that of control group (P < 0.05).

  Conclusion  TEG test parameters are complementary to the level of conventional blood coagulation tests, and it has certain value in the evaluation of short-term prognosis in patients with acute cerebral infarction.