Advance Search
ZHANG Yunbo. Clinical effects of Qishen Yiqi Dripping Pills combined with western medicine for patients with heart failure in vulnerable period[J]. Journal of Clinical Medicine in Practice, 2020, 24(12): 14-17. DOI: 10.7619/jcmp.202012004
Citation: ZHANG Yunbo. Clinical effects of Qishen Yiqi Dripping Pills combined with western medicine for patients with heart failure in vulnerable period[J]. Journal of Clinical Medicine in Practice, 2020, 24(12): 14-17. DOI: 10.7619/jcmp.202012004
shu

Clinical effects of Qishen Yiqi Dripping Pills combined with western medicine for patients with heart failure in vulnerable period

  • Department of General Medicine, The First Affiliated Hospital of Hainan Medical College, Haikou, Hainan, 570102

More Information
  • Received Date: March 14, 2020
    Graphical Abstract
    • Abstract
  • Objective To investigate the effects of Yiqi Dripping Pills combined with western medicine on hemodynamics, left ventricular filling pressure, serum cystatin(CysC), and B-type natriuretic peptide(BNP)in patients with chronic heart failure(CHF)in vulnerable period. Methods Eighty-three patients with heart failure in the vulnerable period who were admitted to our hospital from February 2017 to April 2019 were randomly divided into observation group(n=42)and control group(n=41). The control group was treated with conventional western medicine, and the observation group was treated with QishenYiqi Dripping Pills on the basis of the control group. After 3 months of treatment, the total effective rate, TCM syndrome efficacy, and hemodynamics ［pulmonary capillary wedge pressure(PCWP), mean pulmonary artery pressure(MPAP)and central venous pressure(CVP)］, left ventricular function indicators ［left ventricular ejection fraction(LVEF), ratio of early(E)and late(A)diastolic filling velocities(E/A)at the tip of mitral valve leaflets, the ratio of E to peak velocity of early diastolic wave of the lateral tricuspid annulus(Ea)(E/Ea)］, levels of serum CysC as well as BNP and adverse reactions were compared. Results After treatment, - the total clinical effective rate and TCM symptom effective rate of the observation group were significantly higher than those of the control group(97.62%, 95.24% vs. 82.93%, 80.49%, respectively, P<0.05). After treatment, PCWP, MPAP, and CVP in both groups were decreased, and the observation group was better than the control group(P<0.05). After treatment, E/A, and E/Ea were decreased in both groups, but LVEF was increased, and the observation group was better than the control group(P<0.05). After treatment, the serum CysC and BNP levels of the two groups decreased, and the observation group was lower than the control group(P<0.05). Within 3 months of treatment, the incidence of adverse reactions was 12.20% in the control group and 14.29% in the observation group, but no significant difference in the incidence of adverse reactions between the two groups was found(P>0.05). The re-hospitalization rate in the observation group was lower than that in the control group(9.52% vs. 26.83%, P<0.05). There was no significant difference in mortality rate between the two groups(2.38% in observation group and 4.88% in the control group, P>0.05). Conclusions Qishen Yiqi Dripping Pills combined with western medicine can improve the hemodynamics, reduce the left ventricular filling pressure, and decrease serum CysC and BNP levels, so it is a safe and effective method for CHF patients in vulnerable period.
    • FullText(HTML)
    • References (20)
  • 张国珍, 张卿. 慢性心力衰竭的疗效观察[J]. 内蒙古医科大学学报, 2019, 8(2): 62-68.
    Taneva B, Ristevski D. Coronary stress test as a predictor of quality of life in chronic heart failure patients[J]. Maced Med Rev, 2015, 69(1): 26-29.
    曾军, 廖艳, 常快乐. 氯吡格雷联合芪参益气滴丸对冠心病心衰患者心功能的改善作用分析[J]. 实用心脑肺血管病杂志, 2018, 7(2): 218-220.
    石珂, 贾永平. 心力衰竭易损期再入院率和死亡评估新进展[J]. 中西医结合心脑血管病杂志, 2019, 7(18): 624-630.
    Arruda C S, Pereira J M V, Figueiredo L D S, et al. Effect of an orientation group for patients with chronic heart failure: randomized controlled trial[J]. Rev Lat Am Enfermagem, 2018, 25: e2982-e2988.
    中华医学会心血管病学分会. 慢性心力衰竭诊断治疗指南[J]. 中华心血管病杂志, 2007, 9(12): 1076-1095.
    国家中医药管理局. 中药新药临床研究指导原则(试行)[S]. 北京: 中国医药科技出版社, 2002: 346-350.
    黄德嘉, 张澍. 慢性心力衰竭最佳药物治疗与心脏性猝死的预防[J]. 中华心律失常学杂志, 2018, 22(1): 4-7.
    石珂, 王武祥, 贾永平. 胱抑素C和B型脑钠肽对急性心力衰竭易损期病情评估的比较[J]. 中西医结合心脑血管病杂志, 2019, 7(15): 248-250.
    崔文佳, 王传合, 张琳, 等. 血清白蛋白对射血分数保留型及中间型心力衰竭患者易损期预后的影响[J]. 中国动脉硬化杂志, 2019, 27(6): 507-511.
    Baria A M, Pangarkar S, Abrams G, et al. Adaption of the biopsychosocial model of chronic noncancer pain in veterans[J]. Pain Med, 2019, 20(1): 14-27.
    刘颖, 李争, 张玉焕, 等. 芪参益气汤联合比索洛尔对老年慢性心力衰竭病人BNP及心功能的影响[J]. 中西医结合心脑血管病杂志, 2019, 17(14): 2088-2092.
    陶文其, 黄松群, 黄新苗. 芪苈强心胶囊对老年重度心力衰竭患者的疗效观察[J]. 中国急救复苏与灾害医学杂志, 2019(2): 148-151.
    Hitsumoto T. Clinical significance of skin autofluorescence in patients with type 2 diabetes mellitus with chronic heart failure[J]. Cardiol Res, 2018, 9(2): 83-89.
    高鹏荣, 张建, 刘俊杰, 等. 芪参颗粒对心肌梗死后心力衰竭大鼠心肌纤维化的影响[J]. 中医杂志, 2019, 7(13): 174-180.
    任红杰, 赵安社, 安谊沛, 等. 芪苈强心胶囊联合西药治疗慢性心力衰竭疗效及对患者NT-proBNP、hs-CRP、VEGF的影响[J]. 陕西中医, 2019, 40(6): 711-713.
    Mao G X, Cao Y B, Yang Y, et al. Additive benefits of twice forest bathing trips in elderly patients with chronic heart failure[J]. Biomed Environ Sci, 2018, 31(2): 159-162.
    刘婷, 肖华. 芪参归龙饮联合西药对慢性心力衰竭合并高脂血症老年患者血清心肌肌钙蛋白与骨桥蛋白的影响[J]. 中国中医基础医学杂志, 2019, 25(8): 1108-1110

    , 1133.
    李月亮, 李巧汶, 张国奇. 参芪扶正注射液联合左卡尼汀治疗风湿性心脏病合并心力衰竭的临床研究[J]. 中西医结合心脑血管病杂志, 2019, 17(11): 1677-1680.
    Como J M. Health literacy and health status in people with chronic heart failure[J]. Clin Nurse Spec, 2018, 32(1): 29-42.
    • Related Articles

  • Related Articles

    [1]HE Lan, LU Yang, XIA Zhigang, XIE Xiaoyi, DU Lili, GU Shulian, MA Lan, HE Yongming, SHEN E. A preliminary exploration of a deep learning-based artificial intelligence model for automatic quantification of echocardiographic left ventricular ejection fraction[J]. Journal of Clinical Medicine in Practice, 2024, 28(9): 9-14. DOI: 10.7619/jcmp.20240289
    [2]DAI Yonghui, CHEN Yong. Effect of hyperdynamic left ventricular ejection fraction on prognosis of early septic shock patients[J]. Journal of Clinical Medicine in Practice, 2022, 26(24): 76-80. DOI: 10.7619/jcmp.20222995
    [3]WANG Chunhua, WANG Jun, CHEN Baoding, XIE Yang. Evaluation value of pressure-strain loops in the changes of left ventricular myocardial work in patients with metabolic syndrome[J]. Journal of Clinical Medicine in Practice, 2022, 26(24): 61-65. DOI: 10.7619/jcmp.20223082
    [4]WEN Lu, OUYANG Hui, YUAN Hao, TIAN Jing, ZHANG Fang. Application of B-type brain natriuretic peptide in patients with acute exacerbation of chronic obstructive pulmonary disease with left ventricular ejection fraction retention[J]. Journal of Clinical Medicine in Practice, 2022, 26(24): 46-50. DOI: 10.7619/jcmp.20222662
    [5]SHEN Mengwen, LIN Baibai, QIAN Yiming, ZHAO Lei, ZHU Liang, QIAN Fenghua. Effect of Sini Shengjiang Powder in improving non-invasive hemodynamic indexes of sepsis capillary leakage syndrome[J]. Journal of Clinical Medicine in Practice, 2021, 25(14): 15-19. DOI: 10.7619/jcmp.20211758
    [6]SHI Gang, ZHU Lin, ZHANG Yuhong, ZHAO Yong. Effect of Ginkgo Leaf Extract and Dipyridamole Injection on left ventricular ejection fraction and serum B-type natriuretic peptide in patients with chronic heart failure[J]. Journal of Clinical Medicine in Practice, 2020, 24(18): 44-46. DOI: 10.7619/jcmp.202018012
    [7]ZHANG Liwei. Correlations between serum uric acid, N-terminal pro-B-type natriuretic peptide, vasostatin-2 and left ventricular ejection fraction in patients with chronic heart failure[J]. Journal of Clinical Medicine in Practice, 2020, 24(12): 29-31. DOI: 10.7619/jcmp.202012008
    [8]WANG Rui, LI Jing. Value of echocardiography in assessment of left ventricular morphology and diastolic function in patients with left ventricular diastolic heart failure[J]. Journal of Clinical Medicine in Practice, 2020, 24(3): 10-12. DOI: 10.7619/jcmp.202003003
    [9]CHEN Gang. Correlation between resting heart rate and serum high sensitive C reactive protein, brain natriuretic peptide and left ventricular ejection fraction in patients with chronic heart failure[J]. Journal of Clinical Medicine in Practice, 2019, 23(24): 31-33, 36. DOI: 10.7619/jcmp.201924010
    [10]QU Linnan, CUI Yufang, YU Bin. Effect of early rehabilitation on left ventricular ejection fraction and exercise tolerance in patients with acute myocardial infarction treated by radial artery PCI[J]. Journal of Clinical Medicine in Practice, 2017, (8): 5-7. DOI: 10.7619/jcmp.201708002

  • Cited by

    Periodical cited type(5)

    1. 冯学辉，田龙，胡逸民. 立体定向放射外科治疗脑转移瘤患者颅内出血相关风险因素分析. 国际神经病学神经外科学杂志. 2023(06): 34-39 .
    2. 姜晓颖，张晓磊，翟瑞杰，赵晓燕，任文娟. 维持性血液透析患者脑出血的发生与血脂、血压及营养状态等因素的相关性分析. 系统医学. 2022(14): 1-4 .
    3. 林雪云，石一杰，祝轩，朱会英，邓良彬. 脑微出血与高血压性脑出血转归的关系的纵向研究. 智慧健康. 2021(13): 52-54 .
    4. 张荣，杨鑫泉，熊婷，唐姗，艾可青，钟红艳，毛永清，王大新. GKT137831降低活性氧自由基水平来缓解阿托伐他汀所致的骨骼肌糖摄取下降. 实用临床医药杂志. 2019(10): 53-57 . 本站查看
    5. 黄荣. 他汀类药物治疗脑出血合并高脂血症的效果观察. 基层医学论坛. 2019(29): 4181-4183 .

    Other cited types(0)

Catalog

    Get Citation
    PDF
    XML
    Article views (313) PDF downloads (12) Cited by(5)
    Turn off MathJax
    Article Contents
    Abstract
    References
    Related Articles

    © 2020 《实用临床医药杂志》编辑部

    Address: 江苏省扬州市江阳中路136号，扬州大学江阳路北校区14号楼201室China Pos: 225009Tel: 0514-87978917、87978989、87978807

    苏公网安备 32100302010246号

    Supported by: Beijing Renhe Information Technology Co., Ltd.   Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return