JIANG Ying, JIANG Hongxin, QIAO Ming, YANG Jialing, SU Peiqing. Effect of Sanfen Yuyang Power combined with proton pump inhibitor in treating gastric ulcer with type of blood stasis obstructing meridian[J]. Journal of Clinical Medicine in Practice, 2021, 25(18): 84-86, 92. DOI: 10.7619/jcmp.20210890
Citation: JIANG Ying, JIANG Hongxin, QIAO Ming, YANG Jialing, SU Peiqing. Effect of Sanfen Yuyang Power combined with proton pump inhibitor in treating gastric ulcer with type of blood stasis obstructing meridian[J]. Journal of Clinical Medicine in Practice, 2021, 25(18): 84-86, 92. DOI: 10.7619/jcmp.20210890

Effect of Sanfen Yuyang Power combined with proton pump inhibitor in treating gastric ulcer with type of blood stasis obstructing meridian

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  • Received Date: March 02, 2021
  • Available Online: October 19, 2021
  • Published Date: September 27, 2021
  •   Objective  To observe the clinical effect of Sanfen Yuyang Power combined with proton pump inhibitor (PPI) in the treatment of gastric ulcer with type of blood stasis obstructing meridian.
      Methods  A total of 80 gastric ulcer patients with type of blood stasis obstructing meridians who were negative for Helicobacter pylori (Hp) were randomly divided into two groups. The observation group(n=40) was treated with Sanfen Yuyang Power combined with PPI (rabeprazole), and the control group(n=40) was treated with PPI (rabeprazole). Patients in both groups were treated for a course of 8-week treatment. After treatment, the clinical effects, TCM syndrome scores and improvement degree of gastric ulcer under endoscopy were compared between the two groups.
      Results  The cure rate of the observation group was 52.50%, which was higher than 32.50% of the control group (P < 0.05). After treatment, the improvement condition of gastric ulcer under gastroscopy in the observation group was better than that in the control group (P < 0.05). The scores of primary and secondary symptoms, such as stomachache, pain after eating and nocturnal pain in the observation group were lower than those in the control group (P < 0.05).
      Conclusion  The clinical efficacy of Sanfen Yuyang Power combined with rabeprazole in the treatment of gastric ulcer with type of blood stasis obstructing meridians is superior to the use of rabeprazole, speed up repair of gastric ulcer and improve the healing quality of gastric ulcer.
  • [1]
    中国中西医结合学会消化系统疾病专业委员会. 消化性溃疡中西医结合诊疗共识意见[J]. 中国中西医结合消化杂志, 2018, 26(2): 112-120. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXPW201802002.htm
    [2]
    周建华, 方黎明. 奥美拉唑三联疗法治疗幽门螺杆菌相关性消化性溃疡复发效果观察[J]. 现代实用医学, 2013, 25(10): 1153-1154. doi: 10.3969/j.issn.1671-0800.2013.10.042
    [3]
    卞银燕, 王玉宗, 徐燕芳, 等. 健脾愈疡方联合雷贝拉唑三联疗法治疗消化性溃疡临床研究[J]. 新中医, 2020, 556(9): 78-81. https://www.cnki.com.cn/Article/CJFDTOTAL-REND202009021.htm
    [4]
    中国中西医结合学会消化系统疾病专业委员会. 消化性溃疡中西医结合诊疗共识意见[J]. 中国中西医结合杂志, 2012, 32(6): 733-737. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXPW201802002.htm
    [5]
    朱乐乐, 蔡江怡, 郑伟伟. 蒲翘异功汤联合四联疗法治疗脾胃虚寒证幽门螺杆菌相关性胃溃疡临床研究[J]. 新中医, 2021, 53(3): 68-72. https://www.cnki.com.cn/Article/CJFDTOTAL-REND202103020.htm
    [6]
    王美林, 李丹琪. 黄芪建中汤加减治疗脾胃虚寒型胃溃疡的疗效及血清胃泌素、生长抑素水平的影响[J]. 白求恩医学杂志, 2017, 15(6): 798-799. https://www.cnki.com.cn/Article/CJFDTOTAL-BQEN201706061.htm
    [7]
    许国铭, 李兆申. 上消化道内镜学[M]. 上海: 上海科学技术出版社, 2003: 39-43.
    [8]
    张声生, 王垂杰, 李玉锋, 等. 消化性溃疡中医诊疗专家共识意见(2017)[J]. 中华中医药杂志, 2017, 32(9): 4089-4093. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY201709067.htm
    [9]
    蒋福升, 李美芽, 盛振华, 等. 白芨提取物对炎症因子抑制活性的谱效关系分析[J]. 中药材, 2018, 41(11): 2655-2661.
    [10]
    朱昌玲, 张锋伦. 几种天然产物的抑菌性能研究[J]. 中国野生植物资源, 2017, 36(5): 21-23. doi: 10.3969/j.issn.1006-9690.2017.05.005
    [11]
    刘嵩, 时昭红, 马威, 等. 微米大黄炭白芨胶对胃黏膜损伤的保护作用及机制[J]. 世界华人消化杂志, 2017, 25(10): 874-880. https://www.cnki.com.cn/Article/CJFDTOTAL-XXHB201710005.htm
    [12]
    张磊, 李浩, 魏俊. 三七通舒胶囊治疗脑梗死36例[J]. 河南中医, 2014, 34(11): 2122-2123. https://www.cnki.com.cn/Article/CJFDTOTAL-HNZY201411027.htm
    [13]
    白芳芸, 郑红英, 冯雅宁, 等. 酪酸梭菌联合四联疗法治疗幽门螺杆菌阳性胃溃疡的作用机制研究[J]. 中国现代医学杂志, 2017, 27(9): 83-86. doi: 10.3969/j.issn.1005-8982.2017.09.017
    [14]
    张志令. 中西医结合治疗消化性溃疡的临床观察[J]. 中国中医药现代远程教育, 2017, 15(24): 105-106. doi: 10.3969/j.issn.1672-2779.2017.24.046
    [15]
    朱婷, 冯玉, 肖静, 等. 三七皂苷R1不同给药方式对皮肤创伤愈合作用的影响[J]. 中国药理学通报, 2018, 34(3): 325-330. doi: 10.3969/j.issn.1001-1978.2018.03.007
    [16]
    依超, 温海滨, 覃勋, 等. 三七皂苷R1对高糖诱导HK-2细胞转分化的作用及其机制研究[J]. 广西医科大学学报, 2018, 35(3): 311-314. https://www.cnki.com.cn/Article/CJFDTOTAL-GXYD201803009.htm
    [17]
    宋山峰, 韩文朝, 王晓冰, 等. 三七活血止血作用临床应用研究进展[J]. 中医临床研究, 2016, 8(31): 147-148. doi: 10.3969/j.issn.1674-7860.2016.31.076
    [18]
    张立海, 慈慧, 管涛. 珍珠粉治疗褥疮的临床应用[J]. 首都医药, 2013(20): 60-61. doi: 10.3969/j.issn.1005-8257.2013.20.040
    [19]
    单红君, 蒋菁. 京万红软膏联合珍珠粉治疗皮肤溃疡24例[J]. 浙江中医杂志, 2016, 51(1): 74. https://www.cnki.com.cn/Article/CJFDTOTAL-ZJZZ201601056.htm
    [20]
    曾维勇, 刘忠义. 甲硝唑, 维生素B2, 珍珠粉等配伍治疗口腔溃疡临床研究[J]. 北方药学, 2017, 14(8): 6-8. doi: 10.3969/j.issn.1672-8351.2017.08.005
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